Protein: TCAM2
TIR domain-containing adapter molecule 2 (TICAM-2) (Putative NF-kappa-B-activating protein 502) (TRIF-related adapter molecule) (Toll-like receptor adaptor protein 3) (Toll/interleukin-1 receptor domain-containing protein) (MyD88-4)

Gene: TCAM2, TICAM2
Organism: Homo sapiens
Interactions: 39
UniProt ID: Q86XR7

Gene Ontology (top 5):
GO:0001891 - phagocytic cup
GO:0002735 - positive regulation of myeloid dendritic cell cytokine production
GO:0005768 - endosome
GO:0005769 - early endosome
GO:0005770 - late endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1164528

SARM1
NAD(+) hydrolase SARM1

2

1

Small-scale

0.800

High

120160

TLR4
Toll-like receptor 4

8

8

Small-scale

0.747

High

1204719

TCAM2
TIR domain-containing adapter molecule 2

2

3

Small-scale

0.730

High

1204720

TCAM1
TIR domain-containing adapter molecule 1

4

3

Small-scale

0.683

High

1204730

TRAF6
TNF receptor-associated factor 6

2

11

Small-scale

0.646

High

886010

TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein

1

0

Small-scale

0.631

High

1204726

MYD88
Myeloid differentiation primary response protein MyD88

1

12

Small-scale

0.618

High

969094

KPCE
Protein kinase C epsilon type

1

1

Small-scale

0.536

High

383871

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

1

High-throughput

0.536

High

646047

AVR2A
Activin receptor type-2A

1

1

High-throughput

0.536

High

738372

BMR1A
Bone morphogenetic protein receptor type-1A

1

1

High-throughput

0.536

High

540395

IL1R1
Interleukin-1 receptor type 1

1

1

Small-scale

0.515

High

1204728

IL1AP
Interleukin-1 receptor accessory protein

1

7

Small-scale

0.515

High

516071

CD79A
B-cell antigen receptor complex-associated protein alpha chain

1

0

High-throughput

0.513

High

616832

JAK1
Tyrosine-protein kinase JAK1

1

0

High-throughput

0.513

High

674474

UFO
Tyrosine-protein kinase receptor UFO

1

0

High-throughput

0.513

High

1162082

RHDF2
Inactive rhomboid protein 2

1

0

High-throughput

0.513

High

1204721

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

0

High-throughput

0.513

High

278301

PIAS2
E3 SUMO-protein ligase PIAS2

1

1

High-throughput

0.494

High

592353

RAB5A
Ras-related protein Rab-5A

1

1

High-throughput

0.479

High

182179

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

0

High-throughput

0.458

High

390998

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

1204722

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.458

High

833257

TMEDA
Transmembrane emp24 domain-containing protein 10

1

2

High-throughput

0.445

High

1071785

TMED2
Transmembrane emp24 domain-containing protein 2

1

2

High-throughput

0.445

High

1170663

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1204729

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

123641

PGRC1
Membrane-associated progesterone receptor component 1

1

0

High-throughput

0.426

High

654503

CALX
Calnexin

1

0

High-throughput

0.426

High

1067897

RAGE
Advanced glycosylation end product-specific receptor

1

0

Small-scale

0.426

High

1204723

YIPF5
Protein YIPF5

1

0

High-throughput

0.426

High

1204727

RAB1B
Ras-related protein Rab-1B

1

0

High-throughput

0.426

High

1204725

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.316

High

838097

MEOX2
Homeobox protein MOX-2

1

0

High-throughput

0.299

High

1204724

BSCL2
Seipin

1

0

High-throughput

0.279

Low

365208

FRIH
Ferritin heavy chain

1

0

High-throughput

0.251

Low

1061978

T132D
Transmembrane protein 132D

1

0

Small-scale

0.251

Low

1035490

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024