Protein: KRIT1
Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein)

Gene: KRIT1
Organism: Homo sapiens
Interactions: 40
UniProt ID: O00522

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001937 - negative regulation of endothelial cell proliferation
GO:0003158 - endothelium development
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

131812

ITBP1
Integrin beta-1-binding protein 1

7

0

Small-scale

0.923

High

131840

CCM2
Cerebral cavernous malformations 2 protein

10

1

Small-scale

0.760

High

131848

HEG1
Protein HEG homolog 1

3

11

Small-scale

0.687

High

131833

TEBP
Prostaglandin E synthase 3

2

2

High-throughput

0.628

High

131828

RAP1A
Ras-related protein Rap-1A

1

20

Small-scale

0.621

High

120197

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

131814

RASK
GTPase KRas

1

20

High-throughput

0.618

High

131815

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

131816

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

131819

DAPK1
Death-associated protein kinase 1

1

19

Small-scale

0.618

High

131820

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

131824

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

131826

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.618

High

131827

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

131829

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

131834

RAB35
Ras-related protein Rab-35

1

7

High-throughput

0.618

High

131843

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

131846

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

131822

UBE2K
Ubiquitin-conjugating enzyme E2 K

2

4

High-throughput

0.606

High

131813

NPT2B
Sodium-dependent phosphate transport protein 2B

2

0

High-throughput

0.602

High

131823

RAP1B
Ras-related protein Rap-1b

1

20

Small-scale

0.575

High

131817

TNR6
Tumor necrosis factor receptor superfamily member 6

1

3

Small-scale

0.561

High

131830

PLCB3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

1

3

Small-scale

0.561

High

131821

RAB2A
Ras-related protein Rab-2A

1

4

High-throughput

0.553

High

131839

PI3R4
Phosphoinositide 3-kinase regulatory subunit 4

1

4

Small-scale

0.553

High

131831

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

7

High-throughput

0.541

High

131832

ITPR3
Inositol 1,4,5-trisphosphate receptor type 3

1

1

High-throughput

0.536

High

131844

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

12

High-throughput

0.536

High

131838

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

Small-scale

0.529

High

131845

TRPV4
Transient receptor potential cation channel subfamily V member 4

1

6

Small-scale

0.527

High

131818

RGS4
Regulator of G-protein signaling 4

1

5

Small-scale

0.501

High

131825

ARF6
ADP-ribosylation factor 6

1

2

High-throughput

0.479

High

131835

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

131836

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

1

2

Small-scale

0.479

High

131847

PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

1

3

Small-scale

0.479

High

131849

LAMP3
Lysosome-associated membrane glycoprotein 3

1

5

High-throughput

0.479

High

131837

SNIP1
Smad nuclear-interacting protein 1

1

1

Small-scale

0.437

High

131841

PDC10
Programmed cell death protein 10

1

0

Small-scale

0.426

High

131811

UBFD1
Ubiquitin domain-containing protein UBFD1

2

0

High-throughput

0.328

High

131842

TLRN1
Talin rod domain-containing protein 1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024