Protein: SCD
Stearoyl-CoA desaturase (hSCD1) (EC 1.14.19.1) (Acyl-CoA desaturase) (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase)

Gene: SCD
Organism: Homo sapiens
Interactions: 117
UniProt ID: O00767

Gene Ontology (top 5):
GO:0004768 - stearoyl-CoA 9-desaturase activity
GO:0005506 - iron ion binding
GO:0005730 - nucleolus
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

136137

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

2

1

High-throughput

0.611

High

136141

CXB1
Gap junction beta-1 protein

2

2

High-throughput

0.606

High

136179

MF14B
Hippocampus abundant transcript-like protein 1

2

1

High-throughput

0.606

High

136184

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

3

High-throughput

0.606

High

136235

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

1

High-throughput

0.606

High

136123

MGST3
Glutathione S-transferase 3, mitochondrial

2

0

High-throughput

0.580

High

136146

PVR
Poliovirus receptor

2

0

High-throughput

0.580

High

136149

STOM
Stomatin

2

0

High-throughput

0.580

High

136155

CY561
Transmembrane ascorbate-dependent reductase CYB561

2

0

High-throughput

0.580

High

136174

CC50B
Cell cycle control protein 50B

2

0

High-throughput

0.580

High

136175

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

2

0

High-throughput

0.580

High

136185

RETR3
Reticulophagy regulator 3

2

0

High-throughput

0.580

High

136188

JAGN1
Protein jagunal homolog 1

2

0

High-throughput

0.580

High

136191

MCFD2
Multiple coagulation factor deficiency protein 2

2

0

High-throughput

0.580

High

136198

GPX8
Probable glutathione peroxidase 8

2

0

High-throughput

0.580

High

136202

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

0

High-throughput

0.580

High

136205

TLCD4
TLC domain-containing protein 4

2

0

High-throughput

0.580

High

136209

RNF5
E3 ubiquitin-protein ligase RNF5

2

0

High-throughput

0.580

High

136210

CYBC1
Cytochrome b-245 chaperone 1

2

0

High-throughput

0.580

High

136211

REEP2
Receptor expression-enhancing protein 2

2

0

High-throughput

0.580

High

136213

SC11C
Signal peptidase complex catalytic subunit SEC11C

2

0

High-throughput

0.580

High

136218

IF3M
Translation initiation factor IF-3, mitochondrial

2

0

High-throughput

0.580

High

136223

CERS4
Ceramide synthase 4

2

0

High-throughput

0.580

High

136228

MARH5
E3 ubiquitin-protein ligase MARCHF5

2

0

High-throughput

0.580

High

136229

SCN3B
Sodium channel regulatory subunit beta-3

2

0

High-throughput

0.580

High

136236

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.580

High

136136

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

136148

CD33
Myeloid cell surface antigen CD33

2

1

High-throughput

0.553

High

136168

AQP6
Aquaporin-6

2

1

High-throughput

0.553

High

136172

CL12B
C-type lectin domain family 12 member B

2

2

High-throughput

0.553

High

136195

GP152
Probable G-protein coupled receptor 152

2

2

High-throughput

0.553

High

136233

CLC4K
C-type lectin domain family 4 member K

2

1

High-throughput

0.553

High

123415

PGRC1
Membrane-associated progesterone receptor component 1

1

1

High-throughput

0.536

High

136124

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.536

High

136158

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.536

High

136197

PANK1
Pantothenate kinase 1

1

2

High-throughput

0.536

High

136212

ESYT1
Extended synaptotagmin-1

1

2

High-throughput

0.536

High

136226

RTN4
Reticulon-4

1

1

High-throughput

0.536

High

136230

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.536

High

136138

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.513

High

136143

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

0

High-throughput

0.513

High

136151

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.513

High

136156

PSN1
Presenilin-1

1

0

High-throughput

0.513

High

136194

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

0

High-throughput

0.513

High

136200

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

136219

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

136221

SG196
Protein O-mannose kinase

1

0

High-throughput

0.513

High

136144

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

136183

UBE3B
Ubiquitin-protein ligase E3B

1

2

High-throughput

0.489

High

136214

PANK2
Pantothenate kinase 2, mitochondrial

1

2

High-throughput

0.489

High

136222

PANK3
Pantothenate kinase 3

1

2

High-throughput

0.489

High

136160

VMAT1
Chromaffin granule amine transporter

1

2

High-throughput

0.481

High

136140

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

136130

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

136134

RASN
GTPase NRas

1

2

High-throughput

0.479

High

136135

RASK
GTPase KRas

1

2

High-throughput

0.479

High

136139

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

3

High-throughput

0.479

High

136147

RAC2
Ras-related C3 botulinum toxin substrate 2

1

3

High-throughput

0.479

High

136162

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.479

High

136163

RHOA
Transforming protein RhoA

1

4

High-throughput

0.479

High

136166

RHOG
Rho-related GTP-binding protein RhoG

1

3

High-throughput

0.479

High

136167

CKAP4
Cytoskeleton-associated protein 4

1

2

High-throughput

0.479

High

136189

DHB11
Estradiol 17-beta-dehydrogenase 11

1

3

High-throughput

0.479

High

136207

SEC62
Translocation protein SEC62

1

1

High-throughput

0.479

High

136217

DJC25
DnaJ homolog subfamily C member 25

1

2

High-throughput

0.479

High

136234

AMFR
E3 ubiquitin-protein ligase AMFR

1

1

High-throughput

0.479

High

136128

PJA2
E3 ubiquitin-protein ligase Praja-2

1

0

Small-scale

0.458

High

136131

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.458

High

136132

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

136133

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

136152

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

136161

TERA
Transitional endoplasmic reticulum ATPase

1

0

Small-scale

0.458

High

136164

H4
Histone H4

1

0

High-throughput

0.458

High

136169

CUL3
Cullin-3

1

0

High-throughput

0.458

High

136170

IRF4
Interferon regulatory factor 4

1

0

Small-scale

0.458

High

136176

MIDN
Midnolin

1

0

High-throughput

0.458

High

136196

RBCC1
RB1-inducible coiled-coil protein 1

1

0

High-throughput

0.458

High

136208

CGRF1
Cell growth regulator with RING finger domain protein 1

1

0

High-throughput

0.458

High

136227

S35C2
Solute carrier family 35 member C2

1

1

High-throughput

0.439

High

120199

RHOD
Rho-related GTP-binding protein RhoD

1

4

High-throughput

0.437

High

136142

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

1

High-throughput

0.437

High

136157

RAB7A
Ras-related protein Rab-7a

1

3

High-throughput

0.437

High

136159

RND2
Rho-related GTP-binding protein RhoN

1

6

High-throughput

0.437

High

136165

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

136171

MK06
Mitogen-activated protein kinase 6

1

2

High-throughput

0.437

High

136180

TECT3
Tectonic-3

1

3

High-throughput

0.437

High

136182

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

136186

CXD3
Gap junction delta-3 protein

1

2

High-throughput

0.437

High

136199

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

136203

TECT2
Tectonic-2

1

3

High-throughput

0.437

High

136125

TMPS2
Transmembrane protease serine 2

2

0

High-throughput

0.316

High

136153

KCNJ6
G protein-activated inward rectifier potassium channel 2

2

0

High-throughput

0.316

High

136173

SOAT
Sodium-dependent organic anion transporter

2

0

High-throughput

0.316

High

136193

S7A14
Solute carrier family 7 member 14

2

0

High-throughput

0.316

High

136224

SPAG4
Sperm-associated antigen 4 protein

2

0

High-throughput

0.316

High

136225

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

2

0

High-throughput

0.316

High

136177

RHG15
Rho GTPase-activating protein 15

1

0

High-throughput

0.279

Low

136181

TTC27
Tetratricopeptide repeat protein 27

1

0

High-throughput

0.279

Low

136187

IT70B
Intraflagellar transport protein 70B

1

0

High-throughput

0.279

Low

136215

ASXL3
Putative Polycomb group protein ASXL3

1

0

High-throughput

0.269

Low

136126

GPR42
G-protein coupled receptor 42

1

0

High-throughput

0.268

Low

136206

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

0

High-throughput

0.261

Low

136178

F209A
Protein FAM209A

1

0

High-throughput

0.251

Low

136127

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.249

Low

136129

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.249

Low

136154

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

136190

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

0

Small-scale

0.249

Low

136192

DPTOR
DEP domain-containing mTOR-interacting protein

1

0

Small-scale

0.249

Low

136201

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.249

Low

136204

SNX27
Sorting nexin-27

1

0

High-throughput

0.249

Low

136216

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

0

High-throughput

0.249

Low

136220

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

136231

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

136232

TES
Testin

1

0

High-throughput

0.249

Low

136237

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low

136145

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.232

Low

136150

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024