Protein: EPB41
Protein 4.1 (P4.1) (4.1R) (Band 4.1) (EPB4.1) (Erythrocyte membrane protein band 4.1)

Gene: EPB41
Organism: Homo sapiens
Interactions: 202
UniProt ID: P11171

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005200 - structural constituent of cytoskeleton
GO:0005516 - calmodulin binding
GO:0005545 - 1-phosphatidylinositol binding
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

349088

RASH
GTPase HRas

2

20

High-throughput

0.754

High

349830

RASK
GTPase KRas

2

20

High-throughput

0.754

High

505611

1433G
14-3-3 protein gamma

5

20

High-throughput

0.718

High

505680

E41L1
Band 4.1-like protein 1

1

16

High-throughput

0.691

High

505693

E41L3
Band 4.1-like protein 3

1

16

High-throughput

0.691

High

505634

NUMA1
Nuclear mitotic apparatus protein 1

2

12

Small-scale

0.644

High

505591

ICLN
Methylosome subunit pICln

2

7

High-throughput

0.631

High

127626

EF2K
Eukaryotic elongation factor 2 kinase

2

3

High-throughput

0.628

High

120288

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

348485

RASN
GTPase NRas

1

20

High-throughput

0.618

High

384164

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

433541

LYN
Tyrosine-protein kinase Lyn

1

20

High-throughput

0.618

High

505536

EPB41
Protein 4.1

1

15

Small-scale

0.618

High

505545

EZRI
Ezrin

1

16

High-throughput

0.618

High

505564

UFO
Tyrosine-protein kinase receptor UFO

1

20

Small-scale

0.618

High

505588

RAB5C
Ras-related protein Rab-5C

1

5

High-throughput

0.618

High

505597

RAB25
Ras-related protein Rab-25

1

4

High-throughput

0.618

High

505600

RAB8A
Ras-related protein Rab-8A

1

5

High-throughput

0.618

High

505601

RAB2A
Ras-related protein Rab-2A

1

8

High-throughput

0.618

High

505602

RAB10
Ras-related protein Rab-10

1

5

High-throughput

0.618

High

505614

RB11A
Ras-related protein Rab-11A

1

4

High-throughput

0.618

High

505620

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

505636

RAB35
Ras-related protein Rab-35

1

12

High-throughput

0.618

High

505642

RB11B
Ras-related protein Rab-11B

1

8

High-throughput

0.618

High

505683

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

275787

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

1

Small-scale

0.586

High

505580

YAP1
Transcriptional coactivator YAP1

2

20

Small-scale

0.584

High

505613

ARF6
ADP-ribosylation factor 6

2

6

High-throughput

0.584

High

505551

FGFR3
Fibroblast growth factor receptor 3

1

20

High-throughput

0.575

High

505684

CENPJ
Centromere protein J

1

5

Small-scale

0.573

High

368880

ESR1
Estrogen receptor

2

16

High-throughput

0.571

High

496167

TAU
Microtubule-associated protein tau

2

14

High-throughput

0.571

High

505625

1433F
14-3-3 protein eta

1

20

High-throughput

0.554

High

505687

ZO2
Tight junction protein ZO-2

1

20

Small-scale

0.552

High

159142

CSKP
Peripheral plasma membrane protein CASK

1

20

Small-scale

0.536

High

331194

CHK2
Serine/threonine-protein kinase Chk2

1

5

High-throughput

0.536

High

362745

FINC
Fibronectin

1

4

High-throughput

0.536

High

505612

1433E
14-3-3 protein epsilon

1

6

High-throughput

0.536

High

505637

RNPS1
RNA-binding protein with serine-rich domain 1

1

8

High-throughput

0.536

High

505658

KIBRA
Protein KIBRA

1

20

High-throughput

0.536

High

505668

OPTN
Optineurin

1

17

High-throughput

0.536

High

505663

ZCH10
Zinc finger CCHC domain-containing protein 10

1

6

High-throughput

0.523

High

505554

CDK2
Cyclin-dependent kinase 2

1

2

High-throughput

0.515

High

505556

SYVC
Valine--tRNA ligase

1

2

High-throughput

0.515

High

505558

CALR
Calreticulin

1

1

High-throughput

0.515

High

505568

MYH9
Myosin-9

1

4

High-throughput

0.515

High

505570

TAGL2
Transgelin-2

1

5

High-throughput

0.515

High

505581

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

6

Small-scale

0.515

High

394006

A4
Amyloid-beta precursor protein

1

6

High-throughput

0.515

High

505662

NECP1
Adaptin ear-binding coat-associated protein 1

1

0

High-throughput

0.513

High

505694

C2CD2
C2 domain-containing protein 2

1

0

High-throughput

0.513

High

505537

SPTB1
Spectrin beta chain, erythrocytic

1

19

Small-scale

0.501

High

505590

IMA1
Importin subunit alpha-1

1

2

Small-scale

0.501

High

505627

DLG1
Disks large homolog 1

1

20

Small-scale

0.501

High

505631

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

20

Small-scale

0.501

High

166402

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.493

High

505549

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.493

High

505660

KT222
Keratin-like protein KRT222

1

7

High-throughput

0.489

High

505679

KDM4C
Lysine-specific demethylase 4C

1

2

High-throughput

0.489

High

505690

WDR3
WD repeat-containing protein 3

1

2

High-throughput

0.489

High

351513

ANF
Natriuretic peptides A

1

0

Small-scale

0.480

High

124561

CLIC1
Chloride intracellular channel protein 1

1

2

High-throughput

0.479

High

156209

PSA7
Proteasome subunit alpha type-7

1

2

High-throughput

0.479

High

198219

DC1L2
Cytoplasmic dynein 1 light intermediate chain 2

1

1

High-throughput

0.479

High

204973

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.479

High

212725

STX6
Syntaxin-6

1

2

High-throughput

0.479

High

226356

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

232773

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

10

High-throughput

0.479

High

234892

SNX3
Sorting nexin-3

1

2

High-throughput

0.479

High

273673

NU155
Nuclear pore complex protein Nup155

1

1

High-throughput

0.479

High

279418

FLOT1
Flotillin-1

1

9

High-throughput

0.479

High

298096

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

337195

AATM
Aspartate aminotransferase, mitochondrial

1

1

High-throughput

0.479

High

342541

CAH2
Carbonic anhydrase 2

1

2

High-throughput

0.479

High

385981

P53
Cellular tumor antigen p53

1

6

High-throughput

0.479

High

392738

GLPC
Glycophorin-C

1

8

Small-scale

0.479

High

434332

TPM2
Tropomyosin beta chain

1

1

High-throughput

0.479

High

503318

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

505538

LAMP1
Lysosome-associated membrane glycoprotein 1

1

8

High-throughput

0.479

High

505541

CADH1
Cadherin-1

1

14

High-throughput

0.479

High

505542

MYH1
Myosin-1

1

4

High-throughput

0.479

High

505543

TCTP
Translationally-controlled tumor protein

1

2

High-throughput

0.479

High

505547

PSB1
Proteasome subunit beta type-1

1

4

High-throughput

0.479

High

505548

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

1

High-throughput

0.479

High

505550

SCP2
Sterol carrier protein 2

1

1

High-throughput

0.479

High

505555

PSA1
Proteasome subunit alpha type-1

1

2

High-throughput

0.479

High

505557

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

505559

PSB5
Proteasome subunit beta type-5

1

1

High-throughput

0.479

High

505560

TMOD1
Tropomodulin-1

1

1

High-throughput

0.479

High

505561

MARCS
Myristoylated alanine-rich C-kinase substrate

1

11

High-throughput

0.479

High

505565

STIP1
Stress-induced-phosphoprotein 1

1

4

High-throughput

0.479

High

505567

PROF2
Profilin-2

1

1

High-throughput

0.479

High

505569

MYH10
Myosin-10

1

4

High-throughput

0.479

High

505572

CCNF
Cyclin-F

1

5

High-throughput

0.479

High

505574

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

1

High-throughput

0.479

High

505575

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

20

High-throughput

0.479

High

505577

MUC18
Cell surface glycoprotein MUC18

1

15

High-throughput

0.479

High

505582

ATPO
ATP synthase subunit O, mitochondrial

1

1

High-throughput

0.479

High

505583

GRIA4
Glutamate receptor 4

1

12

Small-scale

0.479

High

505584

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.479

High

505585

SRP09
Signal recognition particle 9 kDa protein

1

2

High-throughput

0.479

High

505586

PSB3
Proteasome subunit beta type-3

1

2

High-throughput

0.479

High

505587

TCPQ
T-complex protein 1 subunit theta

1

5

High-throughput

0.479

High

505593

NH2L1
NHP2-like protein 1

1

2

High-throughput

0.479

High

505598

MTPN
Myotrophin

1

15

High-throughput

0.479

High

505599

PSA6
Proteasome subunit alpha type-6

1

2

High-throughput

0.479

High

505603

UBC12
NEDD8-conjugating enzyme Ubc12

1

1

High-throughput

0.479

High

505604

ABCE1
ATP-binding cassette sub-family E member 1

1

4

High-throughput

0.479

High

505605

RS3A
Small ribosomal subunit protein eS1

1

1

High-throughput

0.479

High

505606

PSME3
Proteasome activator complex subunit 3

1

1

High-throughput

0.479

High

505610

COPZ1
Coatomer subunit zeta-1

1

2

High-throughput

0.479

High

505615

FKB1A
Peptidyl-prolyl cis-trans isomerase FKBP1A

1

1

High-throughput

0.479

High

505616

DYL1
Dynein light chain 1, cytoplasmic

1

2

High-throughput

0.479

High

505618

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

1

High-throughput

0.479

High

505623

CAV1
Caveolin-1

1

5

High-throughput

0.479

High

505624

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

3

High-throughput

0.479

High

505626

DHX9
ATP-dependent RNA helicase A

1

3

High-throughput

0.479

High

505628

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

1

1

High-throughput

0.479

High

505629

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

1

High-throughput

0.479

High

505630

FHL1
Four and a half LIM domains protein 1

1

8

High-throughput

0.479

High

505632

DCTN1
Dynactin subunit 1

1

7

Small-scale

0.479

High

505635

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

505639

TSN
Translin

1

2

High-throughput

0.479

High

505640

SF01
Splicing factor 1

1

3

High-throughput

0.479

High

505641

MARE1
Microtubule-associated protein RP/EB family member 1

1

2

High-throughput

0.479

High

505644

OCLN
Occludin

1

10

High-throughput

0.479

High

505646

MIDN
Midnolin

1

4

High-throughput

0.479

High

505653

RICTR
Rapamycin-insensitive companion of mTOR

1

5

High-throughput

0.479

High

505654

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.479

High

505657

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.479

High

505659

SMC5
Structural maintenance of chromosomes protein 5

1

4

High-throughput

0.479

High

505661

ARL14
ADP-ribosylation factor-like protein 14

1

13

High-throughput

0.479

High

505664

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

5

High-throughput

0.479

High

505669

FMNL2
Formin-like protein 2

1

5

High-throughput

0.479

High

505671

PSB7
Proteasome subunit beta type-7

1

1

High-throughput

0.479

High

505673

PHB2
Prohibitin-2

1

2

High-throughput

0.479

High

505678

WWTR1
WW domain-containing transcription regulator protein 1

1

20

High-throughput

0.479

High

505681

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

505682

CYBP
Calcyclin-binding protein

1

2

High-throughput

0.479

High

505688

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

505689

TR112
Multifunctional methyltransferase subunit TRM112-like protein

1

1

High-throughput

0.479

High

505562

ECHM
Enoyl-CoA hydratase, mitochondrial

1

3

High-throughput

0.470

High

505676

NSD3
Histone-lysine N-methyltransferase NSD3

1

1

High-throughput

0.470

High

336989

PNPH
Purine nucleoside phosphorylase

1

0

High-throughput

0.458

High

337053

HPRT
Hypoxanthine-guanine phosphoribosyltransferase

1

0

High-throughput

0.458

High

376064

CYTB
Cystatin-B

1

0

High-throughput

0.458

High

495447

THIO
Thioredoxin

1

0

High-throughput

0.458

High

505539

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.458

High

505544

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.458

High

505546

CBR1
Carbonyl reductase [NADPH] 1

1

0

High-throughput

0.458

High

505552

EF1B
Elongation factor 1-beta

1

0

High-throughput

0.458

High

505553

PPAC
Low molecular weight phosphotyrosine protein phosphatase

1

0

High-throughput

0.458

High

505563

PEBP1
Phosphatidylethanolamine-binding protein 1

1

0

High-throughput

0.458

High

505578

RANG
Ran-specific GTPase-activating protein

1

0

High-throughput

0.458

High

505579

PRS6B
26S proteasome regulatory subunit 6B

1

0

High-throughput

0.458

High

505589

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

0

High-throughput

0.458

High

505607

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.458

High

505617

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.458

High

505619

PA1B2
Platelet-activating factor acetylhydrolase IB subunit alpha2

1

0

High-throughput

0.458

High

505621

CYC
Cytochrome c

1

0

High-throughput

0.458

High

505622

FABP5
Fatty acid-binding protein 5

1

0

High-throughput

0.458

High

505633

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

0

Small-scale

0.458

High

505638

ELOC
Elongin-C

1

0

High-throughput

0.458

High

505647

Q53Y06
V-type proton ATPase subunit E 1

1

0

High-throughput

0.458

High

505651

Q6FGG2
Vesicle-associated membrane protein 3

1

0

High-throughput

0.458

High

505675

TXD17
Thioredoxin domain-containing protein 17

1

0

High-throughput

0.458

High

505692

HIG1A
HIG1 domain family member 1A, mitochondrial

1

0

High-throughput

0.458

High

505576

HD
Huntingtin

1

5

High-throughput

0.445

High

505594

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

13

High-throughput

0.445

High

505643

NF2L2
Nuclear factor erythroid 2-related factor 2

1

3

High-throughput

0.445

High

505648

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

High-throughput

0.445

High

243844

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.437

High

272020

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

1

High-throughput

0.437

High

505566

S10AB
Protein S100-A11

1

6

High-throughput

0.437

High

505571

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

2

High-throughput

0.437

High

505649

Q5SQT9
GTP-binding protein SAR1a

1

19

High-throughput

0.437

High

505650

DCA15
DDB1- and CUL4-associated factor 15

1

1

High-throughput

0.437

High

505656

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.437

High

505665

ESR2
Estrogen receptor beta

1

16

High-throughput

0.437

High

505666

CK052
Uncharacterized protein C11orf52

1

8

High-throughput

0.437

High

505667

LRC59
Leucine-rich repeat-containing protein 59

1

5

High-throughput

0.437

High

505670

CIC
Protein capicua homolog

1

19

High-throughput

0.437

High

505672

SEC62
Translocation protein SEC62

1

2

High-throughput

0.437

High

505677

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

1

High-throughput

0.437

High

505686

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.437

High

505691

PIN4
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4

1

1

High-throughput

0.437

High

505695

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

1

High-throughput

0.437

High

505655

NEK10
Serine/threonine-protein kinase Nek10

1

10

High-throughput

0.407

High

505595

RWD2B
RWD domain-containing protein 2B

1

0

High-throughput

0.299

High

505645

CP100
Cilia- and flagella-associated protein 100

1

0

High-throughput

0.268

Low

279911

ATP5L
ATP synthase subunit g, mitochondrial

1

0

High-throughput

0.249

Low

495671

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

0

High-throughput

0.249

Low

505540

KCRU
Creatine kinase U-type, mitochondrial

1

0

High-throughput

0.249

Low

505573

EIF1
Eukaryotic translation initiation factor 1

1

0

High-throughput

0.249

Low

505592

KAD2
Adenylate kinase 2, mitochondrial

1

0

High-throughput

0.249

Low

505596

TMM33
Transmembrane protein 33

1

0

High-throughput

0.249

Low

505608

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.249

Low

505609

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

0

High-throughput

0.249

Low

505652

Q6FGH5
Small ribosomal subunit protein eS21

1

0

High-throughput

0.249

Low

505674

RT63
Large ribosomal subunit protein mL63

1

0

High-throughput

0.249

Low

505685

DLRB1
Dynein light chain roadblock-type 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024