Protein: SL9A1
Sodium/hydrogen exchanger 1 (APNH) (Na(+)/H(+) antiporter, amiloride-sensitive) (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1)

Gene: SL9A1, SLC9A1
Organism: Homo sapiens
Interactions: 108
UniProt ID: P19634

Gene Ontology (top 5):
GO:0005516 - calmodulin binding
GO:0005543 - phospholipid binding
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

586063

CHP1
Calcineurin B homologous protein 1

6

20

Small-scale

0.958

High

212564

CHP2
Calcineurin B homologous protein 2

4

20

Small-scale

0.920

High

586058

CHP3
Calcineurin B homologous protein 3

4

20

Small-scale

0.707

High

586010

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

3

High-throughput

0.667

High

586057

LPAR1
Lysophosphatidic acid receptor 1

3

2

High-throughput

0.667

High

349869

RASK
GTPase KRas

3

4

High-throughput

0.640

High

310263

LYPD3
Ly6/PLAUR domain-containing protein 3

3

0

High-throughput

0.638

High

586011

PI2R
Prostacyclin receptor

2

2

High-throughput

0.628

High

586045

GALT7
N-acetylgalactosaminyltransferase 7

2

3

High-throughput

0.628

High

586047

SO6A1
Solute carrier organic anion transporter family member 6A1

2

1

High-throughput

0.628

High

586051

FNDC5
Fibronectin type III domain-containing protein 5

2

2

High-throughput

0.628

High

586059

TECT2
Tectonic-2

2

1

High-throughput

0.628

High

586007

1433B
14-3-3 protein beta/alpha

2

1

Small-scale

0.611

High

342545

CAH2
Carbonic anhydrase 2

2

0

Small-scale

0.607

High

259520

SEM7A
Semaphorin-7A

2

0

High-throughput

0.602

High

585599

FUT1
Galactoside alpha-(1,2)-fucosyltransferase 1

2

0

High-throughput

0.602

High

586038

AOC3
Amine oxidase [copper-containing] 3

2

0

High-throughput

0.602

High

586056

CC107
Coiled-coil domain-containing protein 107

2

0

High-throughput

0.602

High

586071

IPPK
Inositol-pentakisphosphate 2-kinase

2

0

High-throughput

0.602

High

586037

EREP1
Endosomal transmembrane epsin interactor 1

2

0

High-throughput

0.585

High

348503

RASN
GTPase NRas

2

4

High-throughput

0.584

High

586026

RHOB
Rho-related GTP-binding protein RhoB

2

10

High-throughput

0.584

High

586062

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

2

Small-scale

0.578

High

390063

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

2

0

High-throughput

0.559

High

368967

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

324736

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

4

High-throughput

0.541

High

173264

S22A2
Solute carrier family 22 member 2

1

1

High-throughput

0.536

High

310005

5HT3B
5-hydroxytryptamine receptor 3B

1

1

High-throughput

0.536

High

586009

OPRX
Nociceptin receptor

1

2

High-throughput

0.536

High

586018

CCR6
C-C chemokine receptor type 6

1

2

High-throughput

0.536

High

586042

SO4C1
Solute carrier organic anion transporter family member 4C1

1

1

High-throughput

0.536

High

586043

LRC55
Leucine-rich repeat-containing protein 55

1

1

High-throughput

0.536

High

586053

GALT6
Polypeptide N-acetylgalactosaminyltransferase 6

1

3

High-throughput

0.536

High

586054

GP151
G-protein coupled receptor 151

1

3

High-throughput

0.536

High

586077

FPRP
Prostaglandin F2 receptor negative regulator

1

1

High-throughput

0.536

High

586079

DAXX
Death domain-associated protein 6

1

0

Small-scale

0.529

High

586064

MDFI
MyoD family inhibitor

1

0

High-throughput

0.518

High

586013

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

1

Small-scale

0.515

High

586015

ARRB1
Beta-arrestin-1

1

3

Small-scale

0.515

High

353044

IL2RA
Interleukin-2 receptor subunit alpha

1

0

High-throughput

0.513

High

514765

MPRI
Cation-independent mannose-6-phosphate receptor

1

0

High-throughput

0.513

High

586030

X3CL1
Fractalkine

1

0

High-throughput

0.513

High

586032

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.513

High

586039

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

586040

FAXC
Failed axon connections homolog

1

0

High-throughput

0.513

High

586044

LHPL4
LHFPL tetraspan subfamily member 4 protein

1

0

High-throughput

0.513

High

586049

CA210
Type III endosome membrane protein TEMP

1

0

High-throughput

0.513

High

586055

S20A1
Sodium-dependent phosphate transporter 1

1

0

High-throughput

0.513

High

586065

STRA6
Receptor for retinol uptake STRA6

1

0

High-throughput

0.513

High

586067

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

586073

CRLF2
Cytokine receptor-like factor 2

1

0

High-throughput

0.513

High

586081

COA3
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial

1

0

High-throughput

0.513

High

586083

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.513

High

586068

WNK1
Serine/threonine-protein kinase WNK1

1

3

High-throughput

0.481

High

201209

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.480

High

120301

RHOD
Rho-related GTP-binding protein RhoD

1

12

High-throughput

0.479

High

178391

STX7
Syntaxin-7

1

1

High-throughput

0.479

High

318061

DIRA3
GTP-binding protein Di-Ras3

1

1

High-throughput

0.479

High

349115

RASH
GTPase HRas

1

2

High-throughput

0.479

High

436155

RHOC
Rho-related GTP-binding protein RhoC

1

8

High-throughput

0.479

High

545203

RAC2
Ras-related C3 botulinum toxin substrate 2

1

8

High-throughput

0.479

High

564409

RHOQ
Rho-related GTP-binding protein RhoQ

1

10

High-throughput

0.479

High

586008

HSP74
Heat shock 70 kDa protein 4

1

1

Small-scale

0.479

High

586019

RND2
Rho-related GTP-binding protein RhoN

1

10

High-throughput

0.479

High

586021

RAC3
Ras-related C3 botulinum toxin substrate 3

1

9

High-throughput

0.479

High

586022

CDC42
Cell division control protein 42 homolog

1

9

High-throughput

0.479

High

586023

RAB2A
Ras-related protein Rab-2A

1

1

High-throughput

0.479

High

586024

RHOA
Transforming protein RhoA

1

9

High-throughput

0.479

High

586025

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

586027

RAC1
Ras-related C3 botulinum toxin substrate 1

1

9

High-throughput

0.479

High

586031

RHOG
Rho-related GTP-binding protein RhoG

1

8

High-throughput

0.479

High

586033

STX4
Syntaxin-4

1

1

High-throughput

0.479

High

586036

RHOH
Rho-related GTP-binding protein RhoH

1

10

High-throughput

0.479

High

586041

TECT3
Tectonic-3

1

1

High-throughput

0.479

High

586046

TM11B
Transmembrane protease serine 11B

1

1

High-throughput

0.479

High

586069

RHOJ
Rho-related GTP-binding protein RhoJ

1

10

High-throughput

0.479

High

586072

RHOF
Rho-related GTP-binding protein RhoF

1

11

High-throughput

0.479

High

586075

TMPS4
Transmembrane protease serine 4

1

1

High-throughput

0.479

High

163744

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

305354

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.458

High

390707

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

417147

ENOA
Alpha-enolase

1

0

Small-scale

0.458

High

431522

HS90A
Heat shock protein HSP 90-alpha

1

0

Small-scale

0.458

High

521716

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

544936

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

586006

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

Small-scale

0.458

High

586012

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.458

High

586014

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

586016

EMD
Emerin

1

0

High-throughput

0.458

High

586017

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

586020

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

586034

ROCK1
Rho-associated protein kinase 1

1

0

Small-scale

0.458

High

586035

RAB35
Ras-related protein Rab-35

1

0

High-throughput

0.458

High

586050

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.458

High

586052

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.458

High

586060

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

586061

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

586070

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

586074

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.458

High

586076

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.458

High

586078

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

586080

LAMP3
Lysosome-associated membrane glycoprotein 3

1

0

High-throughput

0.458

High

586029

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.457

High

528521

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.445

High

586028

1433Z
14-3-3 protein zeta/delta

1

1

Small-scale

0.445

High

586082

AP4S1
AP-4 complex subunit sigma-1

1

0

High-throughput

0.279

Low

586048

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

586066

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024