Protein: DAB2
Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Differentially-expressed protein 2)

Gene: DAB2
Organism: Homo sapiens
Interactions: 130
UniProt ID: P98082

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001650 - fibrillar center
GO:0001934 - positive regulation of protein phosphorylation
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

394535

A4
Amyloid-beta precursor protein

2

16

Small-scale

0.789

High

957221

MYO6
Unconventional myosin-VI

12

5

Small-scale

0.761

High

957206

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

20

Small-scale

0.747

High

150949

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

17

Small-scale

0.724

High

957172

FCHO2
F-BAR domain only protein 2

4

8

Small-scale

0.705

High

957204

MY18A
Unconventional myosin-XVIIIa

1

2

High-throughput

0.691

High

924477

GRB2
Growth factor receptor-bound protein 2

4

20

Small-scale

0.688

High

150694

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

20

Small-scale

0.647

High

849925

APLP1
Amyloid beta precursor like protein 1

1

15

Small-scale

0.647

High

957169

APLP2
Amyloid beta precursor like protein 2

1

16

Small-scale

0.647

High

957207

SH3K1
SH3 domain-containing kinase-binding protein 1

2

20

Small-scale

0.620

High

451665

CLCB
Clathrin light chain B

2

11

High-throughput

0.611

High

957166

CLH1
Clathrin heavy chain 1

2

5

Small-scale

0.611

High

528976

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

Small-scale

0.585

High

302137

AP2A2
AP-2 complex subunit alpha-2

2

20

Small-scale

0.584

High

451419

CLCA
Clathrin light chain A

2

11

Small-scale

0.584

High

925851

AP2B1
AP-2 complex subunit beta

2

20

Small-scale

0.584

High

414860

CDK1
Cyclin-dependent kinase 1

1

3

Small-scale

0.578

High

950141

SMAD3
Mothers against decapentaplegic homolog 3

1

2

Small-scale

0.578

High

957185

SMAD2
Mothers against decapentaplegic homolog 2

1

2

Small-scale

0.578

High

957165

LRP2
Low-density lipoprotein receptor-related protein 2

1

20

Small-scale

0.573

High

522909

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.561

High

782772

CSK
Tyrosine-protein kinase CSK

1

20

Small-scale

0.561

High

957176

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

1

Small-scale

0.561

High

957190

DAB2P
Disabled homolog 2-interacting protein

1

16

Small-scale

0.561

High

161646

GAK
Cyclin-G-associated kinase

1

10

High-throughput

0.536

High

363075

FINC
Fibronectin

1

2

High-throughput

0.536

High

369405

ESR1
Estrogen receptor

1

15

High-throughput

0.536

High

598065

FLNA
Filamin-A

1

3

High-throughput

0.536

High

724777

MYH9
Myosin-9

1

1

High-throughput

0.536

High

738528

TGFR1
TGF-beta receptor type-1

1

2

Small-scale

0.536

High

739950

TGFR2
TGF-beta receptor type-2

1

2

Small-scale

0.536

High

809265

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

16

High-throughput

0.536

High

812989

CAZA2
F-actin-capping protein subunit alpha-2

1

2

High-throughput

0.536

High

896870

ARP2
Actin-related protein 2

1

6

High-throughput

0.536

High

906415

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

2

High-throughput

0.536

High

957175

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

3

High-throughput

0.536

High

957184

MARE1
Microtubule-associated protein RP/EB family member 1

1

2

High-throughput

0.536

High

957188

DREB
Drebrin

1

4

High-throughput

0.536

High

957189

DCAF6
DDB1- and CUL4-associated factor 6

1

5

High-throughput

0.536

High

957197

SYNPO
Synaptopodin

1

4

High-throughput

0.536

High

957209

REPS1
RalBP1-associated Eps domain-containing protein 1

1

20

High-throughput

0.536

High

957210

MYO19
Unconventional myosin-XIX

1

7

High-throughput

0.536

High

957216

ANLN
Anillin

1

3

High-throughput

0.536

High

957217

BMP2K
BMP-2-inducible protein kinase

1

6

High-throughput

0.536

High

957218

GTSE1
G2 and S phase-expressed protein 1

1

3

High-throughput

0.536

High

957220

LIMA1
LIM domain and actin-binding protein 1

1

4

High-throughput

0.536

High

957223

AKT3
RAC-gamma serine/threonine-protein kinase

1

9

High-throughput

0.536

High

270287

LRP6
Low-density lipoprotein receptor-related protein 6

1

20

Small-scale

0.515

High

820296

SPB4
Serpin B4

1

0

High-throughput

0.513

High

957195

HDGR2
Hepatoma-derived growth factor-related protein 2

1

0

High-throughput

0.513

High

957214

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

4

High-throughput

0.508

High

147151

FCHO1
F-BAR domain only protein 1

1

10

Small-scale

0.501

High

170636

AXIN1
Axin-1

1

2

Small-scale

0.501

High

351065

LDLR
Low-density lipoprotein receptor

1

20

Small-scale

0.501

High

397157

KPCG
Protein kinase C gamma type

1

16

Small-scale

0.501

High

408600

KPCB
Protein kinase C beta type

1

16

Small-scale

0.501

High

454823

FGR
Tyrosine-protein kinase Fgr

1

20

Small-scale

0.501

High

957168

KPCD
Protein kinase C delta type

1

16

Small-scale

0.501

High

957171

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

20

Small-scale

0.501

High

957177

LRP8
Low-density lipoprotein receptor-related protein 8

1

20

Small-scale

0.501

High

957205

SHIP1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

1

4

Small-scale

0.501

High

957211

SGIP1
SH3-containing GRB2-like protein 3-interacting protein 1

1

5

Small-scale

0.501

High

336468

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.493

High

473495

ATX1L
Ataxin-1-like

1

1

High-throughput

0.481

High

957173

CDC16
Cell division cycle protein 16 homolog

1

1

High-throughput

0.481

High

957186

ITSN1
Intersectin-1

1

20

High-throughput

0.481

High

902522

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.480

High

120387

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

160514

AURKA
Aurora kinase A

1

6

Small-scale

0.479

High

162629

XPO1
Exportin-1

1

5

High-throughput

0.479

High

178483

STX7
Syntaxin-7

1

5

High-throughput

0.479

High

205272

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.479

High

212795

STX6
Syntaxin-6

1

7

High-throughput

0.479

High

279856

TRIO
Triple functional domain protein

1

2

Small-scale

0.479

High

315683

SC24B
Protein transport protein Sec24B

1

1

Small-scale

0.479

High

321528

AP2A1
AP-2 complex subunit alpha-1

1

20

Small-scale

0.479

High

338279

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.479

High

397909

ISG15
Ubiquitin-like protein ISG15

1

8

High-throughput

0.479

High

412132

FYN
Tyrosine-protein kinase Fyn

1

20

High-throughput

0.479

High

432658

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

1

High-throughput

0.479

High

540967

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

1

Small-scale

0.479

High

545320

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

557659

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.479

High

607937

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.479

High

655317

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

7

High-throughput

0.479

High

787894

EPS15
Epidermal growth factor receptor substrate 15

1

18

Small-scale

0.479

High

793272

MUC18
Cell surface glycoprotein MUC18

1

5

High-throughput

0.479

High

835324

GSK3A
Glycogen synthase kinase-3 alpha

1

6

High-throughput

0.479

High

835657

GSK3B
Glycogen synthase kinase-3 beta

1

6

High-throughput

0.479

High

891692

ACTB
Actin, cytoplasmic 1

1

5

Small-scale

0.479

High

900375

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

915605

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

925189

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

957167

IFM3
Interferon-induced transmembrane protein 3

1

2

High-throughput

0.479

High

957170

PRDX1
Peroxiredoxin-1

1

1

Small-scale

0.479

High

957178

BECN1
Beclin-1

1

1

Small-scale

0.479

High

957179

TNIP1
TNFAIP3-interacting protein 1

1

7

High-throughput

0.479

High

957180

KIF14
Kinesin-like protein KIF14

1

3

High-throughput

0.479

High

957182

SC23B
Protein transport protein Sec23B

1

1

Small-scale

0.479

High

957183

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

957187

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

5

Small-scale

0.479

High

957191

LTOR1
Ragulator complex protein LAMTOR1

1

5

High-throughput

0.479

High

957193

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

957194

ATG9A
Autophagy-related protein 9A

1

4

High-throughput

0.479

High

957196

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

3

High-throughput

0.479

High

957199

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

1

Small-scale

0.479

High

957201

SMAP2
Stromal membrane-associated protein 2

1

8

High-throughput

0.479

High

957202

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

3

High-throughput

0.479

High

957203

HS105
Heat shock protein 105 kDa

1

3

Small-scale

0.479

High

957208

AP2M1
AP-2 complex subunit mu

1

7

Small-scale

0.479

High

957212

ACE2
Angiotensin-converting enzyme 2

1

3

High-throughput

0.479

High

957215

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

957219

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1

1

9

Small-scale

0.479

High

236747

CCNT1
Cyclin-T1

1

0

Small-scale

0.458

High

273768

NU155
Nuclear pore complex protein Nup155

1

0

Small-scale

0.458

High

403629

AP2A
Transcription factor AP-2-alpha

1

0

Small-scale

0.458

High

617832

SAHH
Adenosylhomocysteinase

1

0

Small-scale

0.458

High

957181

NONO
Non-POU domain-containing octamer-binding protein

1

0

Small-scale

0.458

High

957222

RTRAF
RNA transcription, translation and transport factor protein

1

0

Small-scale

0.458

High

717702

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.445

High

957192

PKHA7
Pleckstrin homology domain-containing family A member 7

1

12

High-throughput

0.445

High

957213

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.445

High

832967

YLPM1
YLP motif-containing protein 1

1

4

Small-scale

0.437

High

376215

ANXA1
Annexin A1

1

0

Small-scale

0.426

High

957198

S2541
Mitochondrial carrier protein SCaMC-3L

3

0

High-throughput

0.347

High

957200

S43A3
Equilibrative nucleobase transporter 1

1

0

High-throughput

0.279

Low

687193

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

1

0

Small-scale

0.249

Low

957174

SF3B2
Splicing factor 3B subunit 2

1

0

Small-scale

0.249

Low

957224

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024