Protein: TENS3
Tensin-3 (EC 3.1.3.-) (Tensin-like SH2 domain-containing protein 1) (Tumor endothelial marker 6)

Gene: TENS3, TNS3
Organism: Homo sapiens
Interactions: 73
UniProt ID: Q68CZ2

Gene Ontology (top 5):
GO:0002102 - podosome
GO:0004721 - phosphoprotein phosphatase activity
GO:0005829 - cytosol
GO:0005925 - focal adhesion
GO:0016311 - dephosphorylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

338552

EGFR
Epidermal growth factor receptor

5

20

Small-scale

0.937

High

782797

CSK
Tyrosine-protein kinase CSK

5

20

High-throughput

0.919

High

882363

BCAR1
Breast cancer anti-estrogen resistance protein 1

2

10

Small-scale

0.819

High

983624

FAK1
Focal adhesion kinase 1

2

20

Small-scale

0.819

High

383853

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

20

High-throughput

0.778

High

523025

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.734

High

601935

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

20

High-throughput

0.696

High

1070975

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.647

High

872663

EPHA4
Ephrin type-A receptor 4

1

16

High-throughput

0.625

High

441520

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.619

High

499273

KIT
Mast/stem cell growth factor receptor Kit

1

13

High-throughput

0.619

High

253750

AUXI
Auxilin

1

13

High-throughput

0.618

High

374384

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

7

High-throughput

0.618

High

1033488

ILK
Integrin-linked protein kinase

1

7

Small-scale

0.618

High

1144542

TENS2
Tensin-2

1

14

High-throughput

0.618

High

1147695

PRAG1
Inactive tyrosine-protein kinase PRAG1

1

1

High-throughput

0.618

High

1147704

M3K20
Mitogen-activated protein kinase kinase kinase 20

1

3

High-throughput

0.618

High

529257

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.585

High

1035381

GAB1
GRB2-associated-binding protein 1

1

6

High-throughput

0.536

High

361354

APOA1
Apolipoprotein A-I

1

1

High-throughput

0.536

High

513871

DMD
Dystrophin

1

18

High-throughput

0.536

High

1033882

SNTB2
Beta-2-syntrophin

1

14

High-throughput

0.536

High

1046435

SNTB1
Beta-1-syntrophin

1

15

High-throughput

0.536

High

1147705

CTNL1
Alpha-catulin

1

2

High-throughput

0.536

High

942729

SRPK2
SRSF protein kinase 2

1

1

High-throughput

0.501

High

246454

DTNB
Dystrobrevin beta

1

11

High-throughput

0.489

High

809130

UTRN
Utrophin

1

14

High-throughput

0.489

High

1147697

P5CR2
Pyrroline-5-carboxylate reductase 2

1

1

High-throughput

0.489

High

120490

RHOD
Rho-related GTP-binding protein RhoD

1

17

High-throughput

0.479

High

162863

XPO1
Exportin-1

1

6

High-throughput

0.479

High

304201

UBR5
E3 ubiquitin-protein ligase UBR5

1

15

High-throughput

0.479

High

322753

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

5

High-throughput

0.479

High

350250

RASK
GTPase KRas

1

7

High-throughput

0.479

High

499827

CH60
60 kDa heat shock protein, mitochondrial

1

4

High-throughput

0.479

High

505728

UMPS
Uridine 5'-monophosphate synthase

1

2

High-throughput

0.479

High

545440

RAC2
Ras-related C3 botulinum toxin substrate 2

1

11

High-throughput

0.479

High

646992

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

683433

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.479

High

684109

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

684811

STIP1
Stress-induced-phosphoprotein 1

1

6

High-throughput

0.479

High

821260

TCPE
T-complex protein 1 subunit epsilon

1

5

High-throughput

0.479

High

823420

PAXI
Paxillin

1

9

High-throughput

0.479

High

835411

GSK3A
Glycogen synthase kinase-3 alpha

1

5

High-throughput

0.479

High

835824

GSK3B
Glycogen synthase kinase-3 beta

1

5

High-throughput

0.479

High

875023

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

904702

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

925353

RAC1
Ras-related C3 botulinum toxin substrate 1

1

12

High-throughput

0.479

High

982129

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

991798

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

1

Small-scale

0.479

High

1146496

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.479

High

1147691

RHOU
Rho-related GTP-binding protein RhoU

1

14

High-throughput

0.479

High

1147694

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

13

High-throughput

0.479

High

1147699

RHG07
Rho GTPase-activating protein 7

1

8

Small-scale

0.479

High

1147700

PASK
PAS domain-containing serine/threonine-protein kinase

1

1

High-throughput

0.479

High

1147701

TCPH
T-complex protein 1 subunit eta

1

5

High-throughput

0.479

High

1147702

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

5

High-throughput

0.479

High

1147703

RHOF
Rho-related GTP-binding protein RhoF

1

16

High-throughput

0.479

High

1147706

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1147707

BAG5
BAG family molecular chaperone regulator 5

1

2

High-throughput

0.479

High

313076

AGM1
Phosphoacetylglucosamine mutase

1

0

High-throughput

0.458

High

1147692

GET4
Golgi to ER traffic protein 4 homolog

1

0

High-throughput

0.458

High

1147698

SPF45
Splicing factor 45

1

1

High-throughput

0.457

High

522000

CADH1
Cadherin-1

1

1

Small-scale

0.457

High

347035

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.437

High

352132

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

2

High-throughput

0.437

High

564569

RHOQ
Rho-related GTP-binding protein RhoQ

1

13

High-throughput

0.437

High

569812

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.437

High

649125

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

4

High-throughput

0.437

High

1043054

CUL4A
Cullin-4A

1

6

High-throughput

0.437

High

1147693

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

7

High-throughput

0.437

High

1147696

ESR2
Estrogen receptor beta

1

15

High-throughput

0.437

High

1147708

HECD1
E3 ubiquitin-protein ligase HECTD1

1

12

High-throughput

0.437

High

353681

IGHG1
Immunoglobulin heavy constant gamma 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024