Protein: PCAT1
Lysophosphatidylcholine acyltransferase 1 (LPC acyltransferase 1) (LPCAT-1) (LysoPC acyltransferase 1) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkenylglycerophosphocholine O-acyltransferase) (EC 2.3.1.25) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 2) (Phosphonoformate immuno-associated protein 3)

Gene: PCAT1, LPCAT1
Organism: Homo sapiens
Interactions: 115
UniProt ID: Q8NF37

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0003841 - 1-acylglycerol-3-phosphate O-acyltransferase activity
GO:0005509 - calcium ion binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

794405

GRK6
G protein-coupled receptor kinase 6

1

2

High-throughput

0.691

High

1160258

PKN3
Serine/threonine-protein kinase N3

1

1

High-throughput

0.691

High

835886

GSK3B
Glycogen synthase kinase-3 beta

1

7

Small-scale

0.647

High

161554

S27A2
Long-chain fatty acid transport protein 2

3

0

High-throughput

0.638

High

1057899

DIP2A
Disco-interacting protein 2 homolog A

3

0

High-throughput

0.638

High

153148

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

3

High-throughput

0.618

High

678569

MK04
Mitogen-activated protein kinase 4

1

13

High-throughput

0.618

High

1224557

CDK20
Cyclin-dependent kinase 20

1

5

High-throughput

0.618

High

1242894

HIPK4
Homeodomain-interacting protein kinase 4

1

15

High-throughput

0.618

High

1244030

NEK7
Serine/threonine-protein kinase Nek7

1

5

High-throughput

0.618

High

1244037

PSKH2
Serine/threonine-protein kinase H2

1

7

High-throughput

0.618

High

1244051

NRBP2
Nuclear receptor-binding protein 2

1

2

High-throughput

0.618

High

1244061

RPKL1
Ribosomal protein S6 kinase-like 1

1

3

High-throughput

0.618

High

1244040

MSTO1
Protein misato homolog 1

3

1

High-throughput

0.609

High

1033512

ILK
Integrin-linked protein kinase

2

0

High-throughput

0.602

High

385191

NTRK1
High affinity nerve growth factor receptor

2

9

High-throughput

0.594

High

883568

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

3

High-throughput

0.575

High

1130343

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

High-throughput

0.575

High

969869

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.553

High

1168892

M3K15
Mitogen-activated protein kinase kinase kinase 15

1

8

High-throughput

0.553

High

1244044

Q9H4D1
Protein kinase

1

3

High-throughput

0.553

High

172130

GP182
G-protein coupled receptor 182

1

9

High-throughput

0.536

High

245378

RAMP3
Receptor activity-modifying protein 3

1

6

High-throughput

0.536

High

326140

TSN15
Tetraspanin-15

1

10

High-throughput

0.536

High

529441

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.536

High

879824

TPTE
Putative tyrosine-protein phosphatase TPTE

1

2

High-throughput

0.536

High

1028508

KLRD1
Natural killer cells antigen CD94

1

5

High-throughput

0.536

High

1153710

STYK1
Tyrosine-protein kinase STYK1

1

3

High-throughput

0.536

High

1191360

ADCK2
Uncharacterized aarF domain-containing protein kinase 2

1

1

High-throughput

0.536

High

1232998

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

3

High-throughput

0.536

High

1244029

COQ8A
Atypical kinase COQ8A, mitochondrial

1

1

High-throughput

0.536

High

1244047

SG196
Protein O-mannose kinase

1

2

High-throughput

0.536

High

557401

BGAL
Beta-galactosidase

1

0

High-throughput

0.513

High

1244057

FBW1A
F-box/WD repeat-containing protein 1A

1

2

Small-scale

0.512

High

175054

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

665632

EPHB2
Ephrin type-B receptor 2

1

3

High-throughput

0.500

High

1040760

PEX6
Peroxisomal ATPase PEX6

1

1

High-throughput

0.489

High

1218833

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.489

High

1240652

ACBD4
Acyl-CoA-binding domain-containing protein 4

1

1

High-throughput

0.489

High

1244059

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

3

High-throughput

0.489

High

120546

RHOD
Rho-related GTP-binding protein RhoD

1

19

High-throughput

0.479

High

163890

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

6

High-throughput

0.479

High

228103

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

350367

RASK
GTPase KRas

1

4

High-throughput

0.479

High

377504

GCR
Glucocorticoid receptor

1

6

High-throughput

0.479

High

390385

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.479

High

391031

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

2

High-throughput

0.479

High

436412

RHOC
Rho-related GTP-binding protein RhoC

1

14

High-throughput

0.479

High

609432

FGFR3
Fibroblast growth factor receptor 3

1

6

High-throughput

0.479

High

632334

TNR6
Tumor necrosis factor receptor superfamily member 6

1

2

High-throughput

0.479

High

795202

SSRA
Translocon-associated protein subunit alpha

1

2

High-throughput

0.479

High

847560

BAP31
B-cell receptor-associated protein 31

1

3

High-throughput

0.479

High

894225

CDC42
Cell division control protein 42 homolog

1

15

High-throughput

0.479

High

900704

RHOA
Transforming protein RhoA

1

16

High-throughput

0.479

High

915841

RHOB
Rho-related GTP-binding protein RhoB

1

16

High-throughput

0.479

High

925447

RAC1
Ras-related C3 botulinum toxin substrate 1

1

14

High-throughput

0.479

High

951167

RHOG
Rho-related GTP-binding protein RhoG

1

13

High-throughput

0.479

High

961740

REEP5
Receptor expression-enhancing protein 5

1

2

High-throughput

0.479

High

966092

LAT1
Large neutral amino acids transporter small subunit 1

1

2

High-throughput

0.479

High

1042078

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1165774

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

1183468

RHOU
Rho-related GTP-binding protein RhoU

1

15

High-throughput

0.479

High

1200850

PAQR2
Adiponectin receptor protein 2

1

3

Small-scale

0.479

High

1204791

GOLI
E3 ubiquitin-protein ligase RNF130

1

4

High-throughput

0.479

High

1230283

CXD3
Gap junction delta-3 protein

1

2

High-throughput

0.479

High

1240210

DHB11
Estradiol 17-beta-dehydrogenase 11

1

4

High-throughput

0.479

High

1240684

RN149
E3 ubiquitin-protein ligase RNF149

1

4

High-throughput

0.479

High

1244034

FBXW7
F-box/WD repeat-containing protein 7

1

2

High-throughput

0.479

High

1244038

SEC62
Translocation protein SEC62

1

3

High-throughput

0.479

High

1244041

DERL1
Derlin-1

1

2

High-throughput

0.479

High

1244045

RHOJ
Rho-related GTP-binding protein RhoJ

1

15

High-throughput

0.479

High

1244046

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.479

High

1244050

RHOF
Rho-related GTP-binding protein RhoF

1

18

High-throughput

0.479

High

1244053

TM216
Transmembrane protein 216

1

3

High-throughput

0.479

High

1244055

TES
Testin

1

1

High-throughput

0.479

High

1244056

AMFR
E3 ubiquitin-protein ligase AMFR

1

1

High-throughput

0.479

High

1244060

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

1

Small-scale

0.479

High

779768

CCNF
Cyclin-F

1

3

High-throughput

0.470

High

504423

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

545001

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

719550

MERL
Merlin

1

0

High-throughput

0.458

High

724447

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

0

Small-scale

0.458

High

868265

ATX3
Ataxin-3

1

0

Small-scale

0.458

High

881651

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.458

High

974933

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

1244042

BBS2
Bardet-Biedl syndrome 2 protein

1

0

High-throughput

0.458

High

1244054

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

0

High-throughput

0.458

High

370042

ESR1
Estrogen receptor

1

6

High-throughput

0.445

High

497320

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.445

High

1241530

MOT11
Monocarboxylate transporter 11

1

4

High-throughput

0.445

High

319273

BRD1
Bromodomain-containing protein 1

1

4

High-throughput

0.437

High

488760

ARAF
Serine/threonine-protein kinase A-Raf

1

1

Small-scale

0.437

High

553225

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

651727

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

720950

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

827978

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

High-throughput

0.437

High

908842

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

941191

RNF4
E3 ubiquitin-protein ligase RNF4

1

3

High-throughput

0.437

High

1170888

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

1244033

ESR2
Estrogen receptor beta

1

6

High-throughput

0.437

High

1244035

OTUL
Ubiquitin thioesterase otulin

1

5

Small-scale

0.437

High

1244049

ECT2
Protein ECT2

1

3

High-throughput

0.437

High

1244052

OTULL
Inactive ubiquitin thioesterase OTULINL

1

5

High-throughput

0.437

High

1244058

AAR2
Protein AAR2 homolog

1

1

High-throughput

0.437

High

1184531

SYPM
Probable proline--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

1244039

METH
Methionine synthase

1

0

High-throughput

0.279

Low

147533

SOCS6
Suppressor of cytokine signaling 6

1

0

High-throughput

0.269

Low

1056896

MDC1
Mediator of DNA damage checkpoint protein 1

1

0

High-throughput

0.249

Low

1086668

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

1148676

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1244031

SAP25
Histone deacetylase complex subunit SAP25

1

0

Small-scale

0.249

Low

1244032

NUDC2
NudC domain-containing protein 2

1

0

High-throughput

0.249

Low

1244036

DOCK7
Dedicator of cytokinesis protein 7

1

0

High-throughput

0.249

Low

1244043

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

1244048

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024