Protein: DEP1B
DEP domain-containing protein 1B (HBV X-transactivated gene 8 protein) (HBV XAg-transactivated protein 8)

Gene: DEP1B, DEPDC1B
Organism: Homo sapiens
Interactions: 189
UniProt ID: Q8WUY9

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0016477 - cell migration
GO:0030177 - positive regulation of Wnt signaling pathway
GO:0035556 - intracellular signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

350395

RASK
GTPase KRas

3

11

High-throughput

0.739

High

348825

RASN
GTPase NRas

2

11

High-throughput

0.675

High

845635

RAB9A
Ras-related protein Rab-9A

2

4

High-throughput

0.675

High

915868

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.675

High

120559

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

253387

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

15

High-throughput

0.618

High

852570

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.618

High

892511

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

900738

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

901208

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.618

High

925474

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1173134

SYDE1
Rho GTPase-activating protein SYDE1

1

15

High-throughput

0.618

High

1260753

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.618

High

1260780

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

1260800

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

8

High-throughput

0.618

High

904913

1433G
14-3-3 protein gamma

3

20

High-throughput

0.604

High

801741

RAGP1
Ran GTPase-activating protein 1

2

2

High-throughput

0.571

High

847031

SMCA4
Transcription activator BRG1

2

6

High-throughput

0.571

High

1260788

ARHGC
Rho guanine nucleotide exchange factor 12

2

8

High-throughput

0.571

High

1260795

CDC23
Cell division cycle protein 23 homolog

2

2

Small-scale

0.560

High

297650

RHBT1
Rho-related BTB domain-containing protein 1

1

20

High-throughput

0.553

High

318195

DIRA3
GTP-binding protein Di-Ras3

1

4

High-throughput

0.553

High

349525

RASH
GTPase HRas

1

8

High-throughput

0.553

High

436432

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.553

High

545526

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.553

High

564629

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.553

High

591643

RAB3B
Ras-related protein Rab-3B

1

2

High-throughput

0.553

High

591953

RAB4A
Ras-related protein Rab-4A

1

4

High-throughput

0.553

High

592402

RAB5A
Ras-related protein Rab-5A

1

4

High-throughput

0.553

High

725506

COPB2
Coatomer subunit beta'

1

2

High-throughput

0.553

High

844650

RAB5C
Ras-related protein Rab-5C

1

4

High-throughput

0.553

High

863501

COPA
Coatomer subunit alpha

1

2

High-throughput

0.553

High

894255

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.553

High

895206

RAB2A
Ras-related protein Rab-2A

1

4

High-throughput

0.553

High

914247

RB11A
Ras-related protein Rab-11A

1

2

High-throughput

0.553

High

951188

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.553

High

1033308

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

4

High-throughput

0.553

High

1070323

RAB35
Ras-related protein Rab-35

1

3

High-throughput

0.553

High

1076682

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.553

High

1146664

A16L1
Autophagy-related protein 16-1

1

10

High-throughput

0.553

High

1183480

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.553

High

1260760

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.553

High

1260772

RHBT2
Rho-related BTB domain-containing protein 2

1

20

High-throughput

0.553

High

1260776

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.553

High

909857

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.536

High

507149

LAMP1
Lysosome-associated membrane glycoprotein 1

2

5

High-throughput

0.533

High

489994

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

2

Small-scale

0.527

High

163055

XPO1
Exportin-1

2

15

High-throughput

0.521

High

300212

PRP6
Pre-mRNA-processing factor 6

2

1

High-throughput

0.521

High

414010

GELS
Gelsolin

2

1

High-throughput

0.521

High

422248

NFL
Neurofilament light polypeptide

2

7

High-throughput

0.521

High

821796

NEST
Nestin

2

12

High-throughput

0.521

High

834645

NU153
Nuclear pore complex protein Nup153

2

6

High-throughput

0.521

High

1061185

NUMA1
Nuclear mitotic apparatus protein 1

2

5

High-throughput

0.521

High

1192136

HUWE1
E3 ubiquitin-protein ligase HUWE1

2

4

High-throughput

0.521

High

1230784

NUP93
Nuclear pore complex protein Nup93

2

3

High-throughput

0.521

High

1235254

NGEF
Ephexin-1

2

9

High-throughput

0.521

High

1246606

COQ8A
Atypical kinase COQ8A, mitochondrial

2

1

High-throughput

0.521

High

1260759

ZFR
Zinc finger RNA-binding protein

2

1

High-throughput

0.521

High

1260767

PKP2
Plakophilin-2

2

5

High-throughput

0.521

High

1260783

SMC4
Structural maintenance of chromosomes protein 4

2

2

High-throughput

0.521

High

927341

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.489

High

957443

IDD
Integral membrane protein DGCR2/IDD

1

2

High-throughput

0.489

High

982324

1433F
14-3-3 protein eta

1

20

High-throughput

0.489

High

1022952

CDC16
Cell division cycle protein 16 homolog

1

2

High-throughput

0.489

High

1260756

ARRD3
Arrestin domain-containing protein 3

1

4

High-throughput

0.489

High

1260757

BSCL2
Seipin

1

1

High-throughput

0.489

High

1260806

BACE2
Beta-secretase 2

1

3

High-throughput

0.489

High

834916

RGS3
Regulator of G-protein signaling 3

1

2

Small-scale

0.481

High

1260804

GRIP1
Glutamate receptor-interacting protein 1

1

10

Small-scale

0.481

High

166592

DCLK1
Serine/threonine-protein kinase DCLK1

1

8

High-throughput

0.479

High

196485

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

1

High-throughput

0.479

High

230899

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

5

High-throughput

0.479

High

608062

FGFR4
Fibroblast growth factor receptor 4

1

14

High-throughput

0.479

High

1260794

LIMA1
LIM domain and actin-binding protein 1

1

3

High-throughput

0.479

High

163903

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.437

High

177702

BIRC5
Baculoviral IAP repeat-containing protein 5

1

1

Small-scale

0.437

High

198678

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

1

High-throughput

0.437

High

205747

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

228176

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.437

High

229447

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

6

High-throughput

0.437

High

232947

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

2

High-throughput

0.437

High

237279

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

1

High-throughput

0.437

High

264368

GGYF1
GRB10-interacting GYF protein 1

1

3

High-throughput

0.437

High

385232

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.437

High

391050

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.437

High

433916

LYN
Tyrosine-protein kinase Lyn

1

16

High-throughput

0.437

High

442338

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

9

High-throughput

0.437

High

527665

LAMP2
Lysosome-associated membrane glycoprotein 2

1

5

High-throughput

0.437

High

547155

EZRI
Ezrin

1

6

High-throughput

0.437

High

567194

CXA1
Gap junction alpha-1 protein

1

2

High-throughput

0.437

High

568743

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

3

High-throughput

0.437

High

657395

ABCD3
ATP-binding cassette sub-family D member 3

1

1

High-throughput

0.437

High

673504

MPIP2
M-phase inducer phosphatase 2

1

1

High-throughput

0.437

High

717233

CTNB1
Catenin beta-1

1

6

Small-scale

0.437

High

719753

RADI
Radixin

1

6

High-throughput

0.437

High

737417

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.437

High

781577

CETN2
Centrin-2

1

2

High-throughput

0.437

High

793409

MUC18
Cell surface glycoprotein MUC18

1

6

High-throughput

0.437

High

800604

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

1

4

Small-scale

0.437

High

874550

XPO2
Exportin-2

1

7

High-throughput

0.437

High

876455

AFAD
Afadin

1

12

High-throughput

0.437

High

877326

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

3

High-throughput

0.437

High

885280

EPIPL
Epiplakin

1

2

High-throughput

0.437

High

913017

ARF6
ADP-ribosylation factor 6

1

5

High-throughput

0.437

High

940508

CXAR
Coxsackievirus and adenovirus receptor

1

6

High-throughput

0.437

High

974947

CAV1
Caveolin-1

1

2

High-throughput

0.437

High

975696

LMNB2
Lamin-B2

1

10

High-throughput

0.437

High

1037853

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

2

High-throughput

0.437

High

1055596

MCM6
DNA replication licensing factor MCM6

1

7

High-throughput

0.437

High

1056904

MDC1
Mediator of DNA damage checkpoint protein 1

1

1

High-throughput

0.437

High

1058783

LBR
Delta(14)-sterol reductase LBR

1

3

High-throughput

0.437

High

1060581

ZN638
Zinc finger protein 638

1

4

High-throughput

0.437

High

1068609

PLEC
Plectin

1

3

High-throughput

0.437

High

1084118

OCLN
Occludin

1

2

High-throughput

0.437

High

1124910

ZN326
DBIRD complex subunit ZNF326

1

1

High-throughput

0.437

High

1131365

HP1B3
Heterochromatin protein 1-binding protein 3

1

1

High-throughput

0.437

High

1136532

SPD2A
SH3 and PX domain-containing protein 2A

1

20

High-throughput

0.437

High

1148996

AN34A
Ankyrin repeat domain-containing protein 34A

1

8

High-throughput

0.437

High

1152004

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.437

High

1153714

STYK1
Tyrosine-protein kinase STYK1

1

16

High-throughput

0.437

High

1156650

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

1202012

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

5

High-throughput

0.437

High

1217968

KSR1
Kinase suppressor of Ras 1

1

9

High-throughput

0.437

High

1230301

CXD3
Gap junction delta-3 protein

1

2

High-throughput

0.437

High

1240223

DHB11
Estradiol 17-beta-dehydrogenase 11

1

3

High-throughput

0.437

High

1253328

F110B
Protein FAM110B

1

1

High-throughput

0.437

High

1256242

DEN1A
DENN domain-containing protein 1A

1

2

High-throughput

0.437

High

1256850

PARD3
Partitioning defective 3 homolog

1

10

High-throughput

0.437

High

1260750

SRS12
Serine/arginine-rich splicing factor 12

1

5

High-throughput

0.437

High

1260751

LAR4B
La-related protein 4B

1

3

High-throughput

0.437

High

1260752

AKAP1
A-kinase anchor protein 1, mitochondrial

1

3

High-throughput

0.437

High

1260755

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

1260758

TECT2
Tectonic-2

1

1

High-throughput

0.437

High

1260763

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

16

High-throughput

0.437

High

1260765

TESK2
Dual specificity testis-specific protein kinase 2

1

1

High-throughput

0.437

High

1260766

RBM15
RNA-binding protein 15

1

5

High-throughput

0.437

High

1260768

DDX50
ATP-dependent RNA helicase DDX50

1

7

High-throughput

0.437

High

1260769

F110A
Protein FAM110A

1

1

High-throughput

0.437

High

1260770

RTKN
Rhotekin

1

1

High-throughput

0.437

High

1260775

DNJC5
DnaJ homolog subfamily C member 5

1

2

High-throughput

0.437

High

1260777

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.437

High

1260778

GHC1
Mitochondrial glutamate carrier 1

1

5

High-throughput

0.437

High

1260779

SFXN1
Sideroflexin-1

1

1

High-throughput

0.437

High

1260782

KI13B
Kinesin-like protein KIF13B

1

3

High-throughput

0.437

High

1260784

MIC19
MICOS complex subunit MIC19

1

1

High-throughput

0.437

High

1260787

MTCH1
Mitochondrial carrier homolog 1

1

6

High-throughput

0.437

High

1260790

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

2

High-throughput

0.437

High

1260791

ANFY1
Rabankyrin-5

1

7

High-throughput

0.437

High

1260793

DNJ5B
DnaJ homolog subfamily C member 5B

1

2

High-throughput

0.437

High

1260797

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

4

High-throughput

0.437

High

1260798

ZBT21
Zinc finger and BTB domain-containing protein 21

1

13

High-throughput

0.437

High

1260799

PPM1H
Protein phosphatase 1H

1

1

High-throughput

0.437

High

1260801

LAMP3
Lysosome-associated membrane glycoprotein 3

1

5

High-throughput

0.437

High

1260803

CBY1
Protein chibby homolog 1

1

2

High-throughput

0.437

High

1260805

KCTD3
BTB/POZ domain-containing protein KCTD3

1

1

High-throughput

0.437

High

1260808

COPG1
Coatomer subunit gamma-1

1

9

High-throughput

0.437

High

526671

GILT
Gamma-interferon-inducible lysosomal thiol reductase

3

0

High-throughput

0.347

High

266214

ERLN1
Erlin-1

2

0

High-throughput

0.298

High

1260807

RT18B
Small ribosomal subunit protein mS40

2

0

High-throughput

0.298

High

1260771

EBPL
Emopamil-binding protein-like

1

0

High-throughput

0.282

High

1243047

ACRBP
Acrosin-binding protein

1

0

High-throughput

0.279

Low

1260773

APC1
Anaphase-promoting complex subunit 1

1

0

High-throughput

0.279

Low

1260796

APC4
Anaphase-promoting complex subunit 4

1

0

High-throughput

0.279

Low

1251660

UHMK1
Serine/threonine-protein kinase Kist

1

0

Small-scale

0.251

Low

132548

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

178694

STX7
Syntaxin-7

1

0

High-throughput

0.249

Low

242519

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

0

High-throughput

0.249

Low

305565

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.249

Low

342574

CAH2
Carbonic anhydrase 2

1

0

High-throughput

0.249

Low

486587

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.249

Low

670132

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.249

Low

687249

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

1

0

High-throughput

0.249

Low

825486

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.249

Low

960394

CDK16
Cyclin-dependent kinase 16

1

0

High-throughput

0.249

Low

1174212

MOB2
MOB kinase activator 2

1

0

High-throughput

0.249

Low

1200522

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.249

Low

1203794

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1260754

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.249

Low

1260761

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

0

High-throughput

0.249

Low

1260762

RAB3I
Rab-3A-interacting protein

1

0

High-throughput

0.249

Low

1260764

PANX1
Pannexin-1

1

0

High-throughput

0.249

Low

1260774

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low

1260781

UBE2T
Ubiquitin-conjugating enzyme E2 T

1

0

Small-scale

0.249

Low

1260785

FA53C
Protein FAM53C

1

0

High-throughput

0.249

Low

1260786

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.249

Low

1260789

SEP10
Septin-10

1

0

High-throughput

0.249

Low

1260792

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.249

Low

1260802

RUVB1
RuvB-like 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024