Protein: TBCD5
TBC1 domain family member 5

Gene: TBCD5, TBC1D5
Organism: Homo sapiens
Interactions: 78
UniProt ID: Q92609

Gene Ontology (top 5):
GO:0002092 - positive regulation of receptor internalization
GO:0005096 - GTPase activator activity
GO:0005776 - autophagosome
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1267962

VPS29
Vacuolar protein sorting-associated protein 29

9

2

Small-scale

0.759

High

264727

VP26A
Vacuolar protein sorting-associated protein 26A

7

2

Small-scale

0.745

High

1116276

VP26B
Vacuolar protein sorting-associated protein 26B

6

2

Small-scale

0.732

High

1267952

VPS35
Vacuolar protein sorting-associated protein 35

6

2

Small-scale

0.729

High

891254

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

5

20

High-throughput

0.713

High

1267955

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

4

20

Small-scale

0.697

High

1267950

AP2M1
AP-2 complex subunit mu

3

1

Small-scale

0.663

High

1188336

ATG9A
Autophagy-related protein 9A

3

1

Small-scale

0.643

High

683590

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.635

High

120566

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

348834

RASN
GTPase NRas

1

20

High-throughput

0.618

High

350412

RASK
GTPase KRas

1

19

High-throughput

0.618

High

545536

RAC2
Ras-related C3 botulinum toxin substrate 2

1

12

High-throughput

0.618

High

591961

RAB4A
Ras-related protein Rab-4A

1

20

High-throughput

0.618

High

845127

RAB7A
Ras-related protein Rab-7a

1

20

High-throughput

0.618

High

845643

RAB9A
Ras-related protein Rab-9A

1

20

High-throughput

0.618

High

884554

RAB25
Ras-related protein Rab-25

1

19

High-throughput

0.618

High

894273

CDC42
Cell division control protein 42 homolog

1

15

High-throughput

0.618

High

900753

RHOA
Transforming protein RhoA

1

15

High-throughput

0.618

High

914259

RB11A
Ras-related protein Rab-11A

1

18

High-throughput

0.618

High

925487

RAC1
Ras-related C3 botulinum toxin substrate 1

1

14

High-throughput

0.618

High

951200

RHOG
Rho-related GTP-binding protein RhoG

1

12

High-throughput

0.618

High

1267959

RHOF
Rho-related GTP-binding protein RhoF

1

18

High-throughput

0.618

High

1267954

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

2

20

Small-scale

0.595

High

868654

ATX1
Ataxin-1

1

2

High-throughput

0.582

High

1267964

FBXL7
F-box/LRR-repeat protein 7

2

0

High-throughput

0.580

High

1238568

EIF1A
Probable RNA-binding protein EIF1AD

2

1

High-throughput

0.576

High

1267956

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

20

Small-scale

0.561

High

904937

1433G
14-3-3 protein gamma

1

20

High-throughput

0.554

High

982349

1433F
14-3-3 protein eta

1

20

High-throughput

0.554

High

1267953

CHIA
Acidic mammalian chitinase

2

1

High-throughput

0.553

High

1076686

RHOH
Rho-related GTP-binding protein RhoH

1

17

High-throughput

0.553

High

1267957

RHOJ
Rho-related GTP-binding protein RhoJ

1

17

High-throughput

0.553

High

647158

1433T
14-3-3 protein theta

1

20

High-throughput

0.536

High

909872

1433E
14-3-3 protein epsilon

1

3

High-throughput

0.536

High

1267949

SPSB4
SPRY domain-containing SOCS box protein 4

1

8

High-throughput

0.536

High

791819

HD
Huntingtin

1

1

High-throughput

0.515

High

476132

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

High-throughput

0.501

High

1267965

DLEC1
Deleted in lung and esophageal cancer protein 1

1

0

High-throughput

0.493

High

875880

MFAP4
Microfibril-associated glycoprotein 4

1

1

High-throughput

0.489

High

1233315

PNKD
Probable hydrolase PNKD

1

1

High-throughput

0.489

High

163071

XPO1
Exportin-1

1

5

High-throughput

0.479

High

205771

TGON2
Trans-Golgi network integral membrane protein 2

1

6

High-throughput

0.479

High

385268

NTRK1
High affinity nerve growth factor receptor

1

14

High-throughput

0.479

High

610464

CBL
E3 ubiquitin-protein ligase CBL

1

1

High-throughput

0.479

High

668863

PML
Protein PML

1

1

High-throughput

0.479

High

684243

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

927363

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

1042181

CUL3
Cullin-3

1

4

High-throughput

0.479

High

1069858

PTPRR
Receptor-type tyrosine-protein phosphatase R

1

2

High-throughput

0.479

High

1206008

MIB1
E3 ubiquitin-protein ligase MIB1

1

2

High-throughput

0.479

High

1267948

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

1267951

SNX27
Sorting nexin-27

1

9

High-throughput

0.479

High

1267963

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

364381

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.458

High

897587

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.458

High

1145068

WAC2A
WASH complex subunit 2A

1

0

Small-scale

0.458

High

1200535

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1267960

NGB
Neuroglobin

1

0

High-throughput

0.458

High

302649

FA13A
Protein FAM13A

1

2

Small-scale

0.457

High

1267961

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.457

High

262295

ULK1
Serine/threonine-protein kinase ULK1

1

2

Small-scale

0.445

High

436105

ANXA6
Annexin A6

1

1

High-throughput

0.437

High

553323

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

651832

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

721053

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

941246

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

1153716

STYK1
Tyrosine-protein kinase STYK1

1

15

High-throughput

0.437

High

1171048

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.437

High

1203798

TMM17
Transmembrane protein 17

1

2

High-throughput

0.437

High

1233393

NIN
Ninein

1

2

High-throughput

0.437

High

1267958

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

255179

ATG13
Autophagy-related protein 13

1

0

Small-scale

0.426

High

1015863

WASC5
WASH complex subunit 5

1

0

Small-scale

0.426

High

622122

ZBT25
Zinc finger and BTB domain-containing protein 25

2

0

High-throughput

0.316

High

1127818

LRC73
Leucine-rich repeat-containing protein 73

1

0

High-throughput

0.279

Low

1220131

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

0

High-throughput

0.269

Low

1267947

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024