Protein: FERM2
Fermitin family homolog 2 (Kindlin-2) (Mitogen-inducible gene 2 protein) (MIG-2) (Pleckstrin homology domain-containing family C member 1) (PH domain-containing family C member 1)

Gene: FERM2, FERMT2
Organism: Homo sapiens
Interactions: 142
UniProt ID: Q96AC1

Gene Ontology (top 5):
GO:0001725 - stress fiber
GO:0003779 - actin binding
GO:0005178 - integrin binding
GO:0005547 - phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1033522

ILK
Integrin-linked protein kinase

2

6

Small-scale

0.812

High

1200427

URP2
Fermitin family homolog 3

2

5

High-throughput

0.811

High

1253155

WDR20
WD repeat-containing protein 20

2

1

High-throughput

0.811

High

1283788

FERM1
Fermitin family homolog 1

2

5

High-throughput

0.811

High

350434

RASK
GTPase KRas

2

6

High-throughput

0.754

High

547171

EZRI
Ezrin

2

3

High-throughput

0.754

High

915888

RHOB
Rho-related GTP-binding protein RhoB

2

12

High-throughput

0.754

High

1260456

FBLI1
Filamin-binding LIM protein 1

1

5

Small-scale

0.740

High

913038

ARF6
ADP-ribosylation factor 6

2

0

High-throughput

0.716

High

914270

RB11A
Ras-related protein Rab-11A

2

0

High-throughput

0.716

High

816268

LIMS1
LIM and senescent cell antigen-like-containing domain protein 1

1

5

Small-scale

0.647

High

717270

CTNB1
Catenin beta-1

2

1

Small-scale

0.639

High

1283796

SMUF1
E3 ubiquitin-protein ligase SMURF1

2

1

Small-scale

0.634

High

1283798

BIRC6
Baculoviral IAP repeat-containing protein 6

2

2

High-throughput

0.621

High

120577

RHOD
Rho-related GTP-binding protein RhoD

1

14

High-throughput

0.618

High

232956

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

3

High-throughput

0.618

High

318201

DIRA3
GTP-binding protein Di-Ras3

1

2

High-throughput

0.618

High

338812

EGFR
Epidermal growth factor receptor

1

8

High-throughput

0.618

High

348848

RASN
GTPase NRas

1

6

High-throughput

0.618

High

349549

RASH
GTPase HRas

1

4

High-throughput

0.618

High

385312

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.618

High

411815

LCK
Tyrosine-protein kinase Lck

1

4

High-throughput

0.618

High

433937

LYN
Tyrosine-protein kinase Lyn

1

4

High-throughput

0.618

High

435723

IGF1R
Insulin-like growth factor 1 receptor

1

7

High-throughput

0.618

High

436448

RHOC
Rho-related GTP-binding protein RhoC

1

10

High-throughput

0.618

High

508139

FGFR1
Fibroblast growth factor receptor 1

1

8

High-throughput

0.618

High

523100

SRC
Proto-oncogene tyrosine-protein kinase Src

1

4

Small-scale

0.618

High

545550

RAC2
Ras-related C3 botulinum toxin substrate 2

1

10

High-throughput

0.618

High

564642

RHOQ
Rho-related GTP-binding protein RhoQ

1

12

High-throughput

0.618

High

592424

RAB5A
Ras-related protein Rab-5A

1

2

High-throughput

0.618

High

608077

FGFR4
Fibroblast growth factor receptor 4

1

8

High-throughput

0.618

High

665642

EPHB2
Ephrin type-B receptor 2

1

3

High-throughput

0.618

High

823465

PAXI
Paxillin

1

5

High-throughput

0.618

High

844673

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.618

High

845655

RAB9A
Ras-related protein Rab-9A

1

2

High-throughput

0.618

High

872687

EPHA4
Ephrin type-A receptor 4

1

5

High-throughput

0.618

High

892531

RAC3
Ras-related C3 botulinum toxin substrate 3

1

11

High-throughput

0.618

High

894293

CDC42
Cell division control protein 42 homolog

1

12

High-throughput

0.618

High

895222

RAB2A
Ras-related protein Rab-2A

1

1

High-throughput

0.618

High

900779

RHOA
Transforming protein RhoA

1

11

High-throughput

0.618

High

901218

RND3
Rho-related GTP-binding protein RhoE

1

15

High-throughput

0.618

High

925505

RAC1
Ras-related C3 botulinum toxin substrate 1

1

11

High-throughput

0.618

High

951217

RHOG
Rho-related GTP-binding protein RhoG

1

10

High-throughput

0.618

High

1044024

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.618

High

1044563

FHL1
Four and a half LIM domains protein 1

1

6

Small-scale

0.618

High

1070337

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.618

High

1071670

KS6A2
Ribosomal protein S6 kinase alpha-2

1

1

High-throughput

0.618

High

1072570

EPHA7
Ephrin type-A receptor 7

1

2

High-throughput

0.618

High

1076701

RHOH
Rho-related GTP-binding protein RhoH

1

12

High-throughput

0.618

High

1081562

NTRK3
NT-3 growth factor receptor

1

7

High-throughput

0.618

High

1110049

AR13B
ADP-ribosylation factor-like protein 13B

1

2

High-throughput

0.618

High

1183499

RHOU
Rho-related GTP-binding protein RhoU

1

14

High-throughput

0.618

High

1266520

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

1

High-throughput

0.618

High

1269201

RND1
Rho-related GTP-binding protein Rho6

1

15

High-throughput

0.618

High

1283783

RHOV
Rho-related GTP-binding protein RhoV

1

12

High-throughput

0.618

High

1283792

RHOJ
Rho-related GTP-binding protein RhoJ

1

12

High-throughput

0.618

High

1283794

RHOF
Rho-related GTP-binding protein RhoF

1

13

High-throughput

0.618

High

1283797

E41LA
Band 4.1-like protein 4A

1

1

High-throughput

0.618

High

341283

FA9
Coagulation factor IX

2

0

High-throughput

0.602

High

1135762

RIPP2
Protein ripply2

2

0

High-throughput

0.602

High

149148

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.586

High

568760

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

High-throughput

0.586

High

228294

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.584

High

507172

LAMP1
Lysosome-associated membrane glycoprotein 1

2

3

High-throughput

0.584

High

1130418

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.575

High

1283801

ARL15
ADP-ribosylation factor-like protein 15

1

2

High-throughput

0.553

High

551237

ITF2
Transcription factor 4

1

0

Small-scale

0.530

High

852128

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

3

High-throughput

0.515

High

175346

LX15B
Polyunsaturated fatty acid lipoxygenase ALOX15B

1

0

High-throughput

0.513

High

818333

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.513

High

1069461

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.513

High

1283785

PRRC1
Protein PRRC1

1

0

High-throughput

0.513

High

1283802

EHD3
EH domain-containing protein 3

1

0

High-throughput

0.513

High

395413

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

403934

ITB1
Integrin beta-1

1

17

Small-scale

0.501

High

1283800

PARVA
Alpha-parvin

1

3

Small-scale

0.501

High

1173299

BBS12
Bardet-Biedl syndrome 12 protein

1

0

High-throughput

0.493

High

1283789

TRI15
E3 ubiquitin-protein ligase TRIM15

1

1

Small-scale

0.481

High

163103

XPO1
Exportin-1

1

1

High-throughput

0.479

High

178714

STX7
Syntaxin-7

1

1

High-throughput

0.479

High

322976

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

347529

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

387256

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

455740

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.479

High

527689

LAMP2
Lysosome-associated membrane glycoprotein 2

1

3

High-throughput

0.479

High

553378

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

567213

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

574564

ITB5
Integrin beta-5

1

17

Small-scale

0.479

High

716744

CTNA1
Catenin alpha-1

1

3

Small-scale

0.479

High

721104

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

742457

SYUA
Alpha-synuclein

1

1

High-throughput

0.479

High

793419

MUC18
Cell surface glycoprotein MUC18

1

1

High-throughput

0.479

High

875196

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.479

High

974970

CAV1
Caveolin-1

1

3

High-throughput

0.479

High

1017746

STX4
Syntaxin-4

1

1

High-throughput

0.479

High

1171134

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

1174277

MOB3C
MOB kinase activator 3C

1

2

High-throughput

0.479

High

1188679

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

1200555

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1230318

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.479

High

1254212

BICD2
Protein bicaudal D homolog 2

1

2

High-throughput

0.479

High

1283780

ARMC5
Armadillo repeat-containing protein 5

1

2

High-throughput

0.479

High

1283791

DNJC5
DnaJ homolog subfamily C member 5

1

1

High-throughput

0.479

High

1283806

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1283807

LAMP3
Lysosome-associated membrane glycoprotein 3

1

3

High-throughput

0.479

High

146055

CLD4
Claudin-4

1

0

Small-scale

0.458

High

205806

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

213856

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

279665

FLOT1
Flotillin-1

1

0

High-throughput

0.458

High

305585

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.458

High

670151

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

840545

VASP
Vasodilator-stimulated phosphoprotein

1

0

High-throughput

0.458

High

931322

YBOX1
Y-box-binding protein 1

1

0

Small-scale

0.458

High

940521

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.458

High

1043152

CUL4A
Cullin-4A

1

0

High-throughput

0.458

High

1084136

OCLN
Occludin

1

0

High-throughput

0.458

High

1152024

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

1230157

CNTRB
Centrobin

1

0

High-throughput

0.458

High

1283784

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.458

High

1283787

FMNL2
Formin-like protein 2

1

0

High-throughput

0.458

High

1283795

CENPJ
Centromere protein J

1

0

High-throughput

0.458

High

442373

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

3

High-throughput

0.457

High

974125

DYST
Dystonin

1

3

High-throughput

0.457

High

1152855

CAPR2
Caprin-2

1

1

High-throughput

0.457

High

1283782

FEM1C
Protein fem-1 homolog C

1

1

High-throughput

0.457

High

1283799

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.457

High

131997

NCHL1
Neural cell adhesion molecule L1-like protein

1

0

High-throughput

0.438

High

207695

SYT7
Synaptotagmin-7

1

0

High-throughput

0.438

High

617007

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

0

High-throughput

0.438

High

1283804

SI1L2
Signal-induced proliferation-associated 1-like protein 2

1

0

High-throughput

0.438

High

1172706

CE128
Centrosomal protein of 128 kDa

1

2

High-throughput

0.437

High

1283805

DNJ5B
DnaJ homolog subfamily C member 5B

1

1

High-throughput

0.437

High

1283808

AP3M1
AP-3 complex subunit mu-1

2

0

High-throughput

0.328

High

648286

G0S2
G0/G1 switch protein 2

1

0

High-throughput

0.279

Low

1283793

GREM2
Gremlin-2

1

0

High-throughput

0.279

Low

1283803

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

0

High-throughput

0.279

Low

1283781

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.265

Low

654645

CALX
Calnexin

1

0

High-throughput

0.249

Low

1203807

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1283027

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low

1283786

HS12B
Heat shock 70 kDa protein 12B

1

0

High-throughput

0.249

Low

1283790

ADSSP
Adipose-secreted signaling protein

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024