Protein: CCM2
Cerebral cavernous malformations 2 protein (Malcavernin)

Gene: CCM2
Organism: Homo sapiens
Interactions: 40
UniProt ID: Q9BSQ5

Gene Ontology (top 5):
GO:0001570 - vasculogenesis
GO:0001701 - in utero embryonic development
GO:0001885 - endothelial cell development
GO:0003158 - endothelium development
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1306371

M3K3
Mitogen-activated protein kinase kinase kinase 3

3

0

Small-scale

0.825

High

131840

KRIT1
Krev interaction trapped protein 1

10

1

Small-scale

0.760

High

152748

ITBP1
Integrin beta-1-binding protein 1

3

0

Small-scale

0.638

High

1044804

RIN1
Ras and Rab interactor 1

3

0

High-throughput

0.636

High

1311567

PDC10
Programmed cell death protein 10

3

0

Small-scale

0.632

High

1311573

STK26
Serine/threonine-protein kinase 26

2

1

High-throughput

0.628

High

1311571

SMUF1
E3 ubiquitin-protein ligase SMURF1

2

1

Small-scale

0.624

High

1311566

CCM2
Cerebral cavernous malformations 2 protein

1

0

Small-scale

0.614

High

1256945

DOK4
Docking protein 4

2

0

High-throughput

0.607

High

1261464

TWST2
Twist-related protein 2

2

0

High-throughput

0.607

High

1298357

VTM2L
V-set and transmembrane domain-containing protein 2-like protein

2

0

High-throughput

0.607

High

1311574

DD19B
ATP-dependent RNA helicase DDX19B

2

0

High-throughput

0.602

High

942910

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.545

High

1290848

NRBF2
Nuclear receptor-binding factor 2

1

0

High-throughput

0.513

High

1301979

NEB2
Neurabin-2

1

0

High-throughput

0.513

High

131601

STK25
Serine/threonine-protein kinase 25

1

1

Small-scale

0.479

High

915928

RHOB
Rho-related GTP-binding protein RhoB

1

3

High-throughput

0.479

High

925569

RAC1
Ras-related C3 botulinum toxin substrate 1

1

1

High-throughput

0.479

High

1311569

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

1

Small-scale

0.479

High

507208

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.458

High

1171471

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

120612

RHOD
Rho-related GTP-binding protein RhoD

1

4

High-throughput

0.437

High

900847

RHOA
Transforming protein RhoA

1

3

Small-scale

0.437

High

1311570

RHOF
Rho-related GTP-binding protein RhoF

1

4

High-throughput

0.437

High

1311568

TLRN1
Talin rod domain-containing protein 1

3

0

High-throughput

0.346

High

224513

RAD21
Double-strand-break repair protein rad21 homolog

2

0

High-throughput

0.328

High

880426

AP1S2
AP-1 complex subunit sigma-2

2

0

High-throughput

0.328

High

1191912

UBE3D
E3 ubiquitin-protein ligase E3D

2

0

High-throughput

0.328

High

678968

HXC8
Homeobox protein Hox-C8

2

0

High-throughput

0.316

High

1311572

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.282

High

156624

PPE1
Serine/threonine-protein phosphatase with EF-hands 1

1

0

High-throughput

0.279

Low

546413

PGAM2
Phosphoglycerate mutase 2

1

0

High-throughput

0.279

Low

1138996

GP107
Protein GPR107

1

0

High-throughput

0.279

Low

1240137

RDH13
Retinol dehydrogenase 13

1

0

High-throughput

0.279

Low

1299987

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.279

Low

1309123

CMS1
Protein CMSS1

1

0

High-throughput

0.279

Low

1311575

KLDC2
Kelch domain-containing protein 2

1

0

High-throughput

0.279

Low

895245

RAB2A
Ras-related protein Rab-2A

1

0

High-throughput

0.249

Low

1251003

SNIP1
Smad nuclear-interacting protein 1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024