Protein: SH3B4
SH3 domain-binding protein 4 (EH-binding protein 10) (Transferrin receptor-trafficking protein)

Gene: SH3B4, SH3BP4
Organism: Homo sapiens
Interactions: 126
UniProt ID: Q9P0V3

Gene Ontology (top 5):
GO:0005092 - GDP-dissociation inhibitor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005905 - clathrin-coated pit
GO:0006897 - endocytosis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

158243

GIPC1
PDZ domain-containing protein GIPC1

4

1

Small-scale

0.913

High

1257223

GIPC2
PDZ domain-containing protein GIPC2

3

1

High-throughput

0.861

High

840844

DYN2
Dynamin-2

2

1

Small-scale

0.776

High

905197

1433G
14-3-3 protein gamma

8

14

Small-scale

0.753

High

683771

1433B
14-3-3 protein beta/alpha

6

14

Small-scale

0.729

High

982565

1433F
14-3-3 protein eta

5

14

Small-scale

0.718

High

647337

1433T
14-3-3 protein theta

5

14

Small-scale

0.716

High

1335082

PKHA1
Pleckstrin homology domain-containing family A member 1

1

0

High-throughput

0.702

High

910108

1433E
14-3-3 protein epsilon

4

2

Small-scale

0.696

High

927602

1433Z
14-3-3 protein zeta/delta

4

14

Small-scale

0.686

High

1081632

NTRK3
NT-3 growth factor receptor

2

0

High-throughput

0.679

High

1349328

ARHGC
Rho guanine nucleotide exchange factor 12

1

0

High-throughput

0.678

High

787986

EPS15
Epidermal growth factor receptor substrate 15

3

1

Small-scale

0.656

High

1349851

SH3B4
SH3 domain-binding protein 4

1

0

Small-scale

0.631

High

1304474

MPP8
M-phase phosphoprotein 8

1

0

High-throughput

0.622

High

983413

DYN1
Dynamin-1

1

1

Small-scale

0.618

High

1300680

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

1

High-throughput

0.618

High

1349861

VSIG4
V-set and immunoglobulin domain-containing protein 4

3

1

High-throughput

0.609

High

684365

1433S
14-3-3 protein sigma

2

14

Small-scale

0.601

High

151230

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.586

High

196516

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

0

High-throughput

0.586

High

253422

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

0

High-throughput

0.586

High

434046

LYN
Tyrosine-protein kinase Lyn

1

0

High-throughput

0.586

High

1136553

SPD2A
SH3 and PX domain-containing protein 2A

1

0

High-throughput

0.586

High

1217993

KSR1
Kinase suppressor of Ras 1

1

0

High-throughput

0.586

High

1301717

TESK2
Dual specificity testis-specific protein kinase 2

1

0

High-throughput

0.586

High

1349860

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

0

High-throughput

0.586

High

916034

RHOB
Rho-related GTP-binding protein RhoB

2

9

High-throughput

0.584

High

364462

TFR1
Transferrin receptor protein 1

1

0

Small-scale

0.576

High

1256909

PARD3
Partitioning defective 3 homolog

1

1

High-throughput

0.553

High

1296934

SNX27
Sorting nexin-27

1

1

High-throughput

0.553

High

1349857

CIZ1
Cip1-interacting zinc finger protein

1

0

High-throughput

0.549

High

529831

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.541

High

1349858

MYO6
Unconventional myosin-VI

1

0

High-throughput

0.530

High

1149006

AN34A
Ankyrin repeat domain-containing protein 34A

1

0

High-throughput

0.517

High

275127

RENR
Renin receptor

1

0

High-throughput

0.513

High

348106

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.513

High

957954

EFNB1
Ephrin-B1

1

0

High-throughput

0.513

High

573509

TCPA
T-complex protein 1 subunit alpha

1

1

High-throughput

0.508

High

826923

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.508

High

403694

AP2A
Transcription factor AP-2-alpha

1

0

Small-scale

0.493

High

1129861

H2B2F
Histone H2B type 2-F

1

0

High-throughput

0.493

High

1060421

KI2S3
Killer cell immunoglobulin-like receptor 2DS3

1

1

High-throughput

0.489

High

147822

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

0

High-throughput

0.486

High

202690

TXNL1
Thioredoxin-like protein 1

1

0

High-throughput

0.486

High

502627

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.486

High

637586

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.486

High

972599

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

0

High-throughput

0.486

High

1262166

DNJA4
DnaJ homolog subfamily A member 4

1

0

High-throughput

0.486

High

1349859

NFU1
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial

1

0

High-throughput

0.486

High

350631

RASK
GTPase KRas

1

1

High-throughput

0.479

High

436551

RHOC
Rho-related GTP-binding protein RhoC

1

7

High-throughput

0.479

High

545671

RAC2
Ras-related C3 botulinum toxin substrate 2

1

7

High-throughput

0.479

High

564715

RHOQ
Rho-related GTP-binding protein RhoQ

1

9

High-throughput

0.479

High

881568

ARL4C
ADP-ribosylation factor-like protein 4C

1

3

High-throughput

0.479

High

892646

RAC3
Ras-related C3 botulinum toxin substrate 3

1

8

High-throughput

0.479

High

894531

CDC42
Cell division control protein 42 homolog

1

9

High-throughput

0.479

High

900996

RHOA
Transforming protein RhoA

1

8

High-throughput

0.479

High

913155

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

925686

RAC1
Ras-related C3 botulinum toxin substrate 1

1

8

High-throughput

0.479

High

950734

ARF5
ADP-ribosylation factor 5

1

1

High-throughput

0.479

High

951423

RHOG
Rho-related GTP-binding protein RhoG

1

7

High-throughput

0.479

High

1066801

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

1076794

RHOH
Rho-related GTP-binding protein RhoH

1

9

High-throughput

0.479

High

1183586

RHOU
Rho-related GTP-binding protein RhoU

1

10

High-throughput

0.479

High

1269798

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1296755

RHOV
Rho-related GTP-binding protein RhoV

1

9

High-throughput

0.479

High

1309178

F110A
Protein FAM110A

1

1

High-throughput

0.479

High

1330962

RHOJ
Rho-related GTP-binding protein RhoJ

1

9

High-throughput

0.479

High

1335360

RHOF
Rho-related GTP-binding protein RhoF

1

10

High-throughput

0.479

High

1343624

KI13B
Kinesin-like protein KIF13B

1

1

High-throughput

0.479

High

1305058

TTC1
Tetratricopeptide repeat protein 1

1

1

High-throughput

0.464

High

178826

STX7
Syntaxin-7

1

0

High-throughput

0.458

High

237333

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.458

High

455954

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

567307

CXA1
Gap junction alpha-1 protein

1

0

High-throughput

0.458

High

673526

MPIP2
M-phase inducer phosphatase 2

1

0

High-throughput

0.458

High

822184

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.458

High

845309

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.458

High

940585

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.458

High

960418

CDK16
Cyclin-dependent kinase 16

1

0

High-throughput

0.458

High

975080

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

1060634

ZN638
Zinc finger protein 638

1

0

High-throughput

0.458

High

1070429

RAB35
Ras-related protein Rab-35

1

0

High-throughput

0.458

High

1172056

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1200363

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

0

High-throughput

0.458

High

1256261

DEN1A
DENN domain-containing protein 1A

1

0

High-throughput

0.458

High

1263465

SRS12
Serine/arginine-rich splicing factor 12

1

0

High-throughput

0.458

High

1283082

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.458

High

1300444

RAB3I
Rab-3A-interacting protein

1

0

High-throughput

0.458

High

1348451

FA53C
Protein FAM53C

1

0

High-throughput

0.458

High

1349853

TES
Testin

1

0

High-throughput

0.458

High

1349855

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

0

High-throughput

0.458

High

1349856

ZBT21
Zinc finger and BTB domain-containing protein 21

1

0

High-throughput

0.458

High

1349862

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.458

High

120686

RHOD
Rho-related GTP-binding protein RhoD

1

11

High-throughput

0.437

High

852657

RND2
Rho-related GTP-binding protein RhoN

1

11

High-throughput

0.437

High

901260

RND3
Rho-related GTP-binding protein RhoE

1

13

High-throughput

0.437

High

1110115

AR13B
ADP-ribosylation factor-like protein 13B

1

2

High-throughput

0.437

High

1173155

SYDE1
Rho GTPase-activating protein SYDE1

1

1

High-throughput

0.437

High

1233620

ARL14
ADP-ribosylation factor-like protein 14

1

2

High-throughput

0.437

High

1253340

F110B
Protein FAM110B

1

1

High-throughput

0.437

High

1269238

RND1
Rho-related GTP-binding protein Rho6

1

12

High-throughput

0.437

High

1060430

KI2S5
Killer cell immunoglobulin-like receptor 2DS5

1

1

High-throughput

0.407

High

832877

TSP3
Thrombospondin-3

3

0

High-throughput

0.347

High

1016746

CETN1
Centrin-1

2

0

High-throughput

0.328

High

1056258

I13R2
Interleukin-13 receptor subunit alpha-2

2

0

High-throughput

0.328

High

1219381

CUL9
Cullin-9

2

0

High-throughput

0.318

High

1330709

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

2

0

High-throughput

0.305

High

1244955

TOIP2
Torsin-1A-interacting protein 2

2

0

High-throughput

0.288

High

1067952

PDCD1
Programmed cell death protein 1

1

0

High-throughput

0.279

Low

1128083

CEP78
Centrosomal protein of 78 kDa

1

0

High-throughput

0.265

Low

1136118

ZBT37
Zinc finger and BTB domain-containing protein 37

1

0

High-throughput

0.265

Low

1137802

GKAP1
G kinase-anchoring protein 1

1

0

High-throughput

0.265

Low

1235187

CB073
Uncharacterized protein C2orf73

1

0

High-throughput

0.265

Low

1314804

PRR14
Proline-rich protein 14

1

0

High-throughput

0.265

Low

1346306

MRGBP
MRG/MORF4L-binding protein

1

0

High-throughput

0.265

Low

166620

DCLK1
Serine/threonine-protein kinase DCLK1

1

0

High-throughput

0.249

Low

264426

GGYF1
GRB10-interacting GYF protein 1

1

0

High-throughput

0.249

Low

793503

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.249

Low

1084215

OCLN
Occludin

1

0

High-throughput

0.249

Low

1109695

TBC25
TBC1 domain family member 25

1

0

High-throughput

0.249

Low

1330424

DNJC5
DnaJ homolog subfamily C member 5

1

0

High-throughput

0.249

Low

1349852

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

0

High-throughput

0.249

Low

1349854

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024