Protein: PUS1
Pseudouridylate synthase 1 homolog (EC 5.4.99.-) (tRNA pseudouridine synthase 1) (EC 5.4.99.12) (tRNA pseudouridine(38-40) synthase) (tRNA pseudouridylate synthase I) (tRNA-uridine isomerase I)

Gene: PUS1
Organism: Homo sapiens
Interactions: 97
UniProt ID: Q9Y606

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0002153 - steroid receptor RNA activator RNA binding
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1347969

THUM1
THUMP domain-containing protein 1

3

1

High-throughput

0.667

High

1124813

OXLD1
Oxidoreductase-like domain-containing protein 1

3

0

High-throughput

0.638

High

827674

EFTU
Elongation factor Tu, mitochondrial

2

1

High-throughput

0.611

High

856874

RM12
Large ribosomal subunit protein bL12m

2

0

High-throughput

0.602

High

1313482

THUM3
tRNA

2

0

High-throughput

0.602

High

799422

EFTS
Elongation factor Ts, mitochondrial

2

0

High-throughput

0.585

High

1331170

MTG2
Mitochondrial ribosome-associated GTPase 2

2

0

High-throughput

0.585

High

229200

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

500254

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.536

High

1046777

KLF5
Krueppel-like factor 5

1

1

High-throughput

0.536

High

1051158

ICT1
Large ribosomal subunit protein mL62

1

1

High-throughput

0.536

High

176318

PPM1G
Protein phosphatase 1G

1

0

High-throughput

0.513

High

212079

GATC
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial

1

0

High-throughput

0.513

High

258837

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

1

0

High-throughput

0.513

High

265923

FRAT2
GSK-3-binding protein FRAT2

1

0

High-throughput

0.513

High

398424

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

0

High-throughput

0.513

High

584111

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

0

High-throughput

0.513

High

622988

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

0

High-throughput

0.513

High

646480

KAD4
Adenylate kinase 4, mitochondrial

1

0

High-throughput

0.513

High

671138

ATPD
ATP synthase subunit delta, mitochondrial

1

0

High-throughput

0.513

High

790291

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

0

High-throughput

0.513

High

815470

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.513

High

885919

YBEY
Endoribonuclease YbeY

1

0

High-throughput

0.513

High

948049

RT11
Small ribosomal subunit protein uS11m

1

0

High-throughput

0.513

High

1159963

FAHD1
Oxaloacetate decarboxylase, mitochondrial

1

0

High-throughput

0.513

High

1187973

RM21
Large ribosomal subunit protein bL21m

1

0

High-throughput

0.513

High

1219156

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1232417

ZN664
Zinc finger protein 664

1

0

High-throughput

0.513

High

1289729

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

0

High-throughput

0.513

High

1295927

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

0

High-throughput

0.513

High

1328023

GATA
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

1

0

High-throughput

0.513

High

1335940

HES4
Transcription factor HES-4

1

0

High-throughput

0.513

High

1346490

EKI2
Ethanolamine kinase 2

1

0

High-throughput

0.513

High

1355504

AMACR
Alpha-methylacyl-CoA racemase

1

0

High-throughput

0.513

High

1355719

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.513

High

1377489

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1378159

RM42
Large ribosomal subunit protein mL42

1

0

High-throughput

0.513

High

348376

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

380077

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

652732

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

721901

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

803294

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.479

High

824595

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

894632

CDC42
Cell division control protein 42 homolog

1

2

High-throughput

0.479

High

901098

RHOA
Transforming protein RhoA

1

2

High-throughput

0.479

High

970105

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

1045913

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.479

High

1076836

RHOH
Rho-related GTP-binding protein RhoH

1

2

High-throughput

0.479

High

1128302

SYAM
Alanine--tRNA ligase, mitochondrial

1

1

High-throughput

0.479

High

1220717

MIRO2
Mitochondrial Rho GTPase 2

1

4

High-throughput

0.479

High

1289046

RRFM
Ribosome-recycling factor, mitochondrial

1

1

High-throughput

0.479

High

1342869

BRD7
Bromodomain-containing protein 7

1

1

High-throughput

0.479

High

1346536

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

1

High-throughput

0.479

High

263048

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.458

High

339204

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

440833

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

486689

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

726492

BASI
Basigin

1

0

High-throughput

0.458

High

777810

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

780406

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

790101

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

881704

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.458

High

909409

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

935433

H31
Histone H3.1

1

0

High-throughput

0.458

High

981505

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

990414

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1036254

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1086164

DUS5
Dual specificity protein phosphatase 5

1

0

High-throughput

0.458

High

1153020

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

1172462

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1189125

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1233505

NIN
Ninein

1

0

High-throughput

0.458

High

1297224

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.458

High

1307083

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

1331755

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1333149

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1333421

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1333845

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

1347370

RMND1
Required for meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.458

High

1349783

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

1355029

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1356387

FBW1B
F-box/WD repeat-containing protein 11

1

0

High-throughput

0.458

High

120737

RHOD
Rho-related GTP-binding protein RhoD

1

4

High-throughput

0.437

High

1331013

RHOJ
Rho-related GTP-binding protein RhoJ

1

2

High-throughput

0.437

High

1335423

RHOF
Rho-related GTP-binding protein RhoF

1

3

High-throughput

0.437

High

1343252

TRPV5
Transient receptor potential cation channel subfamily V member 5

3

0

High-throughput

0.347

High

152394

ABCD4
Lysosomal cobalamin transporter ABCD4

1

0

High-throughput

0.279

Low

261932

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

0

High-throughput

0.279

Low

1232170

PARP8
Protein mono-ADP-ribosyltransferase PARP8

1

0

High-throughput

0.279

Low

1260364

NU133
Nuclear pore complex protein Nup133

1

0

High-throughput

0.279

Low

1377802

KIF3A
Kinesin-like protein KIF3A

1

0

High-throughput

0.279

Low

1377992

PCDBB
Protocadherin beta-11

1

0

High-throughput

0.279

Low

1378158

EMIL1
EMILIN-1

1

0

High-throughput

0.279

Low

155490

NRP1
Neuropilin-1

1

0

High-throughput

0.249

Low

198313

DC1L2
Cytoplasmic dynein 1 light intermediate chain 2

1

0

High-throughput

0.249

Low

1316855

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low

1345103

TMPS4
Transmembrane protease serine 4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024