Protein: HEMO
Hemopexin (Beta-1B-glycoprotein)

Gene: HEMO, HPX
Organism: Homo sapiens
Interactions: 70
UniProt ID: P02790

Gene Ontology (top 5):
GO:0002639 - positive regulation of immunoglobulin production
GO:0002925 - positive regulation of humoral immune response mediated by circulating immunoglobulin
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006879 - intracellular iron ion homeostasis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

364794

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

3

2

High-throughput

0.662

High

364795

GDPD1
Lysophospholipase D GDPD1

3

0

High-throughput

0.638

High

364765

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

2

High-throughput

0.571

High

364769

FGFR1
Fibroblast growth factor receptor 1

2

3

High-throughput

0.571

High

364777

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

2

1

High-throughput

0.571

High

364782

CDC42
Cell division control protein 42 homolog

2

1

High-throughput

0.571

High

364774

PEBP1
Phosphatidylethanolamine-binding protein 1

2

0

High-throughput

0.547

High

364813

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

2

0

High-throughput

0.547

High

126340

MATN2
Matrilin-2

1

10

High-throughput

0.536

High

198360

KLK10
Kallikrein-10

1

7

High-throughput

0.536

High

363676

ALBU
Albumin

1

1

High-throughput

0.536

High

364787

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

2

High-throughput

0.536

High

364803

EGFL8
Epidermal growth factor-like protein 8

1

3

High-throughput

0.536

High

364808

MBNL1
Muscleblind-like protein 1

1

1

High-throughput

0.536

High

364811

PHF11
PHD finger protein 11

1

1

High-throughput

0.536

High

364771

BRAF
Serine/threonine-protein kinase B-raf

2

2

High-throughput

0.521

High

331690

NSD2
Histone-lysine N-methyltransferase NSD2

1

0

High-throughput

0.513

High

364797

HMGC2
3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic

1

0

High-throughput

0.513

High

364766

HS90A
Heat shock protein HSP 90-alpha

1

1

Small-scale

0.501

High

364770

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.489

High

364776

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.489

High

364785

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

1

High-throughput

0.489

High

364791

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

1

High-throughput

0.489

High

364798

RHBL4
Rhomboid-related protein 4

1

3

High-throughput

0.489

High

364799

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

2

High-throughput

0.489

High

364800

SARAF
Store-operated calcium entry-associated regulatory factor

1

1

High-throughput

0.489

High

364802

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

1

High-throughput

0.489

High

364812

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

3

High-throughput

0.489

High

364805

P63
Tumor protein 63

1

1

High-throughput

0.481

High

121071

LEG8
Galectin-8

1

5

Small-scale

0.479

High

341180

HPT
Haptoglobin

1

1

High-throughput

0.479

High

344144

A1AT
Alpha-1-antitrypsin

1

2

High-throughput

0.479

High

344261

AACT
Alpha-1-antichymotrypsin

1

2

High-throughput

0.479

High

361287

APOA1
Apolipoprotein A-I

1

2

High-throughput

0.479

High

361802

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

2

High-throughput

0.479

High

363990

VTDB
Vitamin D-binding protein

1

1

High-throughput

0.479

High

364768

CLUS
Clusterin

1

3

High-throughput

0.479

High

364772

LEG3
Galectin-3

1

5

Small-scale

0.479

High

364775

LCN1
Lipocalin-1

1

2

High-throughput

0.479

High

364784

HBB
Hemoglobin subunit beta

1

1

High-throughput

0.479

High

364810

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

1

High-throughput

0.479

High

336758

CERU
Ceruloplasmin

1

0

High-throughput

0.458

High

363419

A1AG1
Alpha-1-acid glycoprotein 1

1

0

High-throughput

0.458

High

364500

TRFE
Serotransferrin

1

0

High-throughput

0.458

High

364764

STAT
Statherin

1

0

High-throughput

0.458

High

364773

ZA2G
Zinc-alpha-2-glycoprotein

1

0

High-throughput

0.458

High

364780

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

364789

PROL4
Proline-rich protein 4

1

0

High-throughput

0.458

High

364809

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

364767

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

4

High-throughput

0.457

High

364786

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

2

Small-scale

0.445

High

364788

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

1

High-throughput

0.445

High

335019

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

1

High-throughput

0.439

High

325586

LATS1
Serine/threonine-protein kinase LATS1

1

1

High-throughput

0.437

High

364778

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.437

High

364796

FBX22
F-box only protein 22

1

2

High-throughput

0.437

High

364790

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

364801

SNX27
Sorting nexin-27

2

0

High-throughput

0.328

High

364806

DDX31
ATP-dependent DNA helicase DDX31

2

0

High-throughput

0.328

High

183012

P2RX6
P2X purinoceptor 6

1

0

High-throughput

0.279

Low

217705

PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

1

0

High-throughput

0.279

Low

296848

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.279

Low

364779

PTSS1
Phosphatidylserine synthase 1

1

0

High-throughput

0.279

Low

364781

STX17
Syntaxin-17

1

0

High-throughput

0.279

Low

364792

SFXN4
Sideroflexin-4

1

0

High-throughput

0.279

Low

364793

CIR1
Corepressor interacting with RBPJ 1

1

0

High-throughput

0.279

Low

364807

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.279

Low

364814

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.279

Low

364804

URM1
Ubiquitin-related modifier 1

1

0

Small-scale

0.261

Low

364783

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024