Protein: TNFL8
Tumor necrosis factor ligand superfamily member 8 (CD30 ligand) (CD30-L) (CD antigen CD153)

Gene: TNFL8, TNFSF8
Organism: Homo sapiens
Interactions: 139
UniProt ID: P32971

Gene Ontology (top 5):
GO:0005102 - signaling receptor binding
GO:0005125 - cytokine activity
GO:0005164 - tumor necrosis factor receptor binding
GO:0005615 - extracellular space
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

702333

TNFL9
Tumor necrosis factor ligand superfamily member 9

2

0

High-throughput

0.770

High

702343

PTPRS
Receptor-type tyrosine-protein phosphatase S

2

0

High-throughput

0.770

High

702354

CDON
Cell adhesion molecule-related/down-regulated by oncogenes

2

0

High-throughput

0.770

High

661039

TNR8
Tumor necrosis factor receptor superfamily member 8

2

0

Small-scale

0.728

High

545075

PVR
Poliovirus receptor

1

2

High-throughput

0.691

High

702389

NECT2
Nectin-2

1

2

High-throughput

0.691

High

600517

EPHA1
Ephrin type-A receptor 1

1

0

High-throughput

0.656

High

702429

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

0

High-throughput

0.656

High

518556

FA5
Coagulation factor V

2

1

High-throughput

0.628

High

570486

PTN2
Tyrosine-protein phosphatase non-receptor type 2

2

1

High-throughput

0.628

High

702336

AGRE5
Adhesion G protein-coupled receptor E5

2

3

High-throughput

0.628

High

702338

HBA
Hemoglobin subunit alpha

2

1

High-throughput

0.628

High

702340

EFNB1
Ephrin-B1

2

1

High-throughput

0.628

High

702350

EFNB3
Ephrin-B3

2

1

High-throughput

0.628

High

702402

ULBP3
UL16-binding protein 3

2

3

High-throughput

0.628

High

702403

ULBP2
UL16-binding protein 2

2

2

High-throughput

0.628

High

702404

ULBP1
UL16-binding protein 1

2

2

High-throughput

0.628

High

312999

BMP10
Bone morphogenetic protein 10

2

1

High-throughput

0.606

High

685807

ARRB2
Beta-arrestin-2

2

0

High-throughput

0.602

High

702330

RYK
Tyrosine-protein kinase RYK

2

0

High-throughput

0.602

High

702345

DAG1
Dystroglycan 1

2

0

High-throughput

0.602

High

702351

OCLN
Occludin

2

0

High-throughput

0.602

High

702374

FGRL1
Fibroblast growth factor receptor-like 1

2

0

High-throughput

0.602

High

702394

RB39B
Ras-related protein Rab-39B

2

0

High-throughput

0.602

High

702397

S39A3
Zinc transporter ZIP3

2

0

High-throughput

0.602

High

702406

SEM4C
Semaphorin-4C

2

0

High-throughput

0.602

High

702426

PDXL2
Podocalyxin-like protein 2

2

0

High-throughput

0.602

High

702341

CXCL9
C-X-C motif chemokine 9

2

0

High-throughput

0.580

High

702380

CADM4
Cell adhesion molecule 4

1

0

High-throughput

0.578

High

355135

HBD
Hemoglobin subunit delta

2

1

High-throughput

0.574

High

702344

ATR
Serine/threonine-protein kinase ATR

2

1

High-throughput

0.574

High

702378

DCBD1
Discoidin, CUB and LCCL domain-containing protein 1

2

1

High-throughput

0.574

High

702381

MFSD8
Major facilitator superfamily domain-containing protein 8

2

1

High-throughput

0.574

High

518094

ADT1
ADP/ATP translocase 1

1

1

High-throughput

0.536

High

520106

BMP4
Bone morphogenetic protein 4

1

1

High-throughput

0.536

High

530841

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

1

High-throughput

0.536

High

702352

MICB
MHC class I polypeptide-related sequence B

1

1

High-throughput

0.536

High

702353

MICA
MHC class I polypeptide-related sequence A

1

1

High-throughput

0.536

High

702355

LRC24
Leucine-rich repeat-containing protein 24

1

1

High-throughput

0.536

High

702360

AGRF1
Adhesion G-protein coupled receptor F1

1

3

High-throughput

0.536

High

702367

PCAT2
Lysophosphatidylcholine acyltransferase 2

1

1

High-throughput

0.536

High

702370

AGRG6
Adhesion G-protein coupled receptor G6

1

3

High-throughput

0.536

High

702379

CNNM3
Metal transporter CNNM3

1

1

High-throughput

0.536

High

702392

S22AI
Solute carrier family 22 member 18

1

1

High-throughput

0.536

High

702413

CNNM2
Metal transporter CNNM2

1

1

High-throughput

0.536

High

702419

ITM2C
Integral membrane protein 2C

1

1

High-throughput

0.536

High

702431

AGRE2
Adhesion G protein-coupled receptor E2

1

3

High-throughput

0.536

High

702436

ITM2B
Integral membrane protein 2B

1

1

High-throughput

0.536

High

121116

LEG8
Galectin-8

1

0

High-throughput

0.513

High

183354

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

1

0

High-throughput

0.513

High

234787

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

0

High-throughput

0.513

High

532868

TF
Tissue factor

1

0

High-throughput

0.513

High

599773

5NTD
5'-nucleotidase

1

0

High-throughput

0.513

High

702331

TGFR1
TGF-beta receptor type-1

1

0

High-throughput

0.513

High

702335

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

1

0

High-throughput

0.513

High

702342

DDR1
Epithelial discoidin domain-containing receptor 1

1

0

High-throughput

0.513

High

702357

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

702364

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

0

High-throughput

0.513

High

702366

TBA1A
Tubulin alpha-1A chain

1

0

High-throughput

0.513

High

702371

NLRX1
NLR family member X1

1

0

High-throughput

0.513

High

702372

C1QL4
Complement C1q-like protein 4

1

0

High-throughput

0.513

High

702376

FBCD1
Fibrinogen C domain-containing protein 1

1

0

High-throughput

0.513

High

702383

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.513

High

702399

S26A6
Solute carrier family 26 member 6

1

0

High-throughput

0.513

High

702401

KPCD2
Serine/threonine-protein kinase D2

1

0

High-throughput

0.513

High

702411

SMOC1
SPARC-related modular calcium-binding protein 1

1

0

High-throughput

0.513

High

702412

ANTR1
Anthrax toxin receptor 1

1

0

High-throughput

0.513

High

702415

LPAR2
Lysophosphatidic acid receptor 2

1

0

High-throughput

0.513

High

702418

GPC5C
G-protein coupled receptor family C group 5 member C

1

0

High-throughput

0.513

High

702425

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

0

High-throughput

0.513

High

702435

XCT
Cystine/glutamate transporter

1

0

High-throughput

0.513

High

518261

ADT3
ADP/ATP translocase 3

1

1

High-throughput

0.489

High

702334

MTOR
Serine/threonine-protein kinase mTOR

1

1

High-throughput

0.489

High

702361

LPCT4
Lysophospholipid acyltransferase LPCAT4

1

1

High-throughput

0.489

High

702363

SFXN4
Sideroflexin-4

1

2

High-throughput

0.489

High

702377

S2529
Mitochondrial basic amino acids transporter

1

2

High-throughput

0.489

High

702384

S2540
Mitochondrial glutathione transporter SLC25A40

1

3

High-throughput

0.489

High

702390

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

1

High-throughput

0.489

High

702395

SFXN2
Sideroflexin-2

1

2

High-throughput

0.489

High

702398

SFXN3
Sideroflexin-3

1

2

High-throughput

0.489

High

702416

TPC
Mitochondrial thiamine pyrophosphate carrier

1

2

High-throughput

0.489

High

152083

TOR1B
Torsin-1B

2

0

High-throughput

0.328

High

276690

GATB
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial

2

0

High-throughput

0.328

High

702337

NEK3
Serine/threonine-protein kinase Nek3

2

0

High-throughput

0.328

High

702365

DHR13
Dehydrogenase/reductase SDR family member 13

2

0

High-throughput

0.328

High

702386

NEUFC
Neuferricin

2

0

High-throughput

0.328

High

702393

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

2

0

High-throughput

0.328

High

702396

CP2S1
Cytochrome P450 2S1

2

0

High-throughput

0.328

High

702430

COMD3
COMM domain-containing protein 3

2

0

High-throughput

0.328

High

135577

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

0

High-throughput

0.279

Low

155725

HS3S1
Heparan sulfate glucosamine 3-O-sulfotransferase 1

1

0

High-throughput

0.279

Low

178118

IPO8
Importin-8

1

0

High-throughput

0.279

Low

260179

MPU1
Mannose-P-dolichol utilization defect 1 protein

1

0

High-throughput

0.279

Low

301182

RHBT3
Rho-related BTB domain-containing protein 3

1

0

High-throughput

0.279

Low

313061

AGM1
Phosphoacetylglucosamine mutase

1

0

High-throughput

0.279

Low

318310

ASML
Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein [Includes: dTTP/UTP pyrophosphatase

1

0

High-throughput

0.279

Low

318465

CDS2
Phosphatidate cytidylyltransferase 2

1

0

High-throughput

0.279

Low

321333

STR3N
STARD3 N-terminal-like protein

1

0

High-throughput

0.279

Low

702328

ERD22
ER lumen protein-retaining receptor 2

1

0

High-throughput

0.279

Low

702329

MCM7
DNA replication licensing factor MCM7

1

0

High-throughput

0.279

Low

702332

RFC3
Replication factor C subunit 3

1

0

High-throughput

0.279

Low

702339

HTRA3
Serine protease HTRA3

1

0

High-throughput

0.279

Low

702346

OXA1L
Mitochondrial inner membrane protein OXA1L

1

0

High-throughput

0.279

Low

702347

PGFRL
Platelet-derived growth factor receptor-like protein

1

0

High-throughput

0.279

Low

702348

UBE3C
Ubiquitin-protein ligase E3C

1

0

High-throughput

0.279

Low

702349

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.279

Low

702356

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

0

High-throughput

0.279

Low

702358

SYEM
Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial

1

0

High-throughput

0.279

Low

702359

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

702362

ACD10
Acyl-CoA dehydrogenase family member 10

1

0

High-throughput

0.279

Low

702368

MON2
Protein MON2 homolog

1

0

High-throughput

0.279

Low

702369

SCD5
Stearoyl-CoA desaturase 5

1

0

High-throughput

0.279

Low

702373

RPTOR
Regulatory-associated protein of mTOR

1

0

High-throughput

0.279

Low

702375

CBR4
3-oxoacyl-[acyl-carrier-protein] reductase

1

0

High-throughput

0.279

Low

702382

GDAP1
Ganglioside-induced differentiation-associated protein 1

1

0

High-throughput

0.279

Low

702385

GPX8
Probable glutathione peroxidase 8

1

0

High-throughput

0.279

Low

702387

PTCD2
Pentatricopeptide repeat-containing protein 2, mitochondrial

1

0

High-throughput

0.279

Low

702388

ELYS
Protein ELYS

1

0

High-throughput

0.279

Low

702391

FAKD4
FAST kinase domain-containing protein 4

1

0

High-throughput

0.279

Low

702400

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

0

High-throughput

0.279

Low

702405

UCK2
Uridine-cytidine kinase 2

1

0

High-throughput

0.279

Low

702407

DERL2
Derlin-2

1

0

High-throughput

0.279

Low

702408

SRR
Serine racemase

1

0

High-throughput

0.279

Low

702409

LMA2L
VIP36-like protein

1

0

High-throughput

0.279

Low

702410

SPNS1
Protein spinster homolog 1

1

0

High-throughput

0.279

Low

702414

L2HDH
L-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

702417

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.279

Low

702420

PLCE
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

1

0

High-throughput

0.279

Low

702421

AP5S1
AP-5 complex subunit sigma-1

1

0

High-throughput

0.279

Low

702422

INT7
Integrator complex subunit 7

1

0

High-throughput

0.279

Low

702423

ARL8B
ADP-ribosylation factor-like protein 8B

1

0

High-throughput

0.279

Low

702424

CLN6
Ceroid-lipofuscinosis neuronal protein 6

1

0

High-throughput

0.279

Low

702427

CNIH4
Protein cornichon homolog 4

1

0

High-throughput

0.279

Low

702428

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.279

Low

702432

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

0

High-throughput

0.279

Low

702433

TM59L
Transmembrane protein 59-like

1

0

High-throughput

0.279

Low

702434

MA1B1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

0

High-throughput

0.279

Low

702437

C2CD2
C2 domain-containing protein 2

1

0

High-throughput

0.279

Low

702438

ALG5
Dolichyl-phosphate beta-glucosyltransferase

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024