Protein: WBP2
WW domain-binding protein 2 (WBP-2)

Gene: WBP2
Organism: Homo sapiens
Interactions: 81
UniProt ID: Q969T9

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

808826

YAP1
Transcriptional coactivator YAP1

9

12

Small-scale

0.754

High

808210

NEDD4
E3 ubiquitin-protein ligase NEDD4

7

7

Small-scale

0.751

High

125630

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

7

7

Small-scale

0.744

High

1282381

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

5

7

Small-scale

0.708

High

1282371

ITCH
E3 ubiquitin-protein ligase Itchy homolog

4

7

Small-scale

0.697

High

1282386

HOME3
Homer protein homolog 3

3

1

Small-scale

0.672

High

324546

BAG3
BAG family molecular chaperone regulator 3

4

0

High-throughput

0.663

High

1282372

NED4L
E3 ubiquitin-protein ligase NEDD4-like

3

7

Small-scale

0.647

High

1282379

WWTR1
WW domain-containing transcription regulator protein 1

2

12

Small-scale

0.646

High

1282388

WWOX
WW domain-containing oxidoreductase

3

0

High-throughput

0.627

High

307553

EPN2
Epsin-2

3

0

Small-scale

0.626

High

795832

MAGA4
Melanoma-associated antigen 4

2

1

High-throughput

0.584

High

121202

LEG8
Galectin-8

2

0

High-throughput

0.580

High

1282319

UB2E3
Ubiquitin-conjugating enzyme E2 E3

2

0

High-throughput

0.580

High

1282376

SMAD5
Mothers against decapentaplegic homolog 5

2

0

High-throughput

0.580

High

1282377

TCPH
T-complex protein 1 subunit eta

2

0

High-throughput

0.580

High

370159

ESR1
Estrogen receptor

1

1

Small-scale

0.561

High

1282392

WWC3
Protein WWC3

1

10

Small-scale

0.561

High

1282373

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

2

3

Small-scale

0.553

High

417386

ENOA
Alpha-enolase

1

0

Small-scale

0.537

High

983205

UBE3A
Ubiquitin-protein ligase E3A

1

8

Small-scale

0.527

High

964388

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.518

High

1093446

Q1RN33
Melanoma antigen A 4

1

1

High-throughput

0.515

High

1282375

CGRF1
Cell growth regulator with RING finger domain protein 1

1

0

High-throughput

0.513

High

725513

COPB2
Coatomer subunit beta'

1

1

Small-scale

0.501

High

863509

COPA
Coatomer subunit alpha

1

1

Small-scale

0.501

High

1282397

COPG1
Coatomer subunit gamma-1

1

1

Small-scale

0.501

High

1282398

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

0

High-throughput

0.493

High

476156

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

Small-scale

0.481

High

924105

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

3

Small-scale

0.481

High

924376

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

3

Small-scale

0.481

High

1172517

AN13D
Ankyrin repeat domain-containing protein 13D

1

1

Small-scale

0.481

High

1192157

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

7

Small-scale

0.481

High

1223853

AN13A
Ankyrin repeat domain-containing protein 13A

1

1

Small-scale

0.481

High

1282394

UBQL1
Ubiquilin-1

1

4

Small-scale

0.481

High

149701

COPE
Coatomer subunit epsilon

1

0

Small-scale

0.480

High

408889

K1C18
Keratin, type I cytoskeletal 18

1

0

Small-scale

0.480

High

409187

K2C8
Keratin, type II cytoskeletal 8

1

0

Small-scale

0.480

High

616447

RS3
Small ribosomal subunit protein uS3

1

0

Small-scale

0.480

High

623161

EF1B
Elongation factor 1-beta

1

0

Small-scale

0.480

High

724118

K1C9
Keratin, type I cytoskeletal 9

1

0

Small-scale

0.480

High

818989

COPD
Coatomer subunit delta

1

0

Small-scale

0.480

High

863289

COPB
Coatomer subunit beta

1

0

Small-scale

0.480

High

917705

H4
Histone H4

1

0

Small-scale

0.480

High

1271617

DDX17
Probable ATP-dependent RNA helicase DDX17

1

0

Small-scale

0.480

High

1282385

GRPE1
GrpE protein homolog 1, mitochondrial

1

0

Small-scale

0.480

High

428351

TBB5
Tubulin beta chain

1

1

Small-scale

0.479

High

443706

VIME
Vimentin

1

2

Small-scale

0.479

High

535507

GFAP
Glial fibrillary acidic protein

1

2

Small-scale

0.479

High

719574

MERL
Merlin

1

2

High-throughput

0.479

High

840542

VASP
Vasodilator-stimulated phosphoprotein

1

3

Small-scale

0.479

High

875193

TERA
Transitional endoplasmic reticulum ATPase

1

1

Small-scale

0.479

High

1171119

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1274326

MED12
Mediator of RNA polymerase II transcription subunit 12

1

2

High-throughput

0.479

High

1282390

UBQL2
Ubiquilin-2

1

4

High-throughput

0.479

High

1282391

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

1

Small-scale

0.479

High

1282378

RAB34
Ras-related protein Rab-34

1

1

High-throughput

0.470

High

316342

TYDP2
Tyrosyl-DNA phosphodiesterase 2

1

0

Small-scale

0.460

High

1223723

RN168
E3 ubiquitin-protein ligase RNF168

1

0

Small-scale

0.460

High

1282374

UIMC1
BRCA1-A complex subunit RAP80

1

0

Small-scale

0.460

High

1282380

TOLIP
Toll-interacting protein

1

0

Small-scale

0.460

High

1282383

APC1
Anaphase-promoting complex subunit 1

1

0

Small-scale

0.460

High

1282393

MYO6
Unconventional myosin-VI

1

0

Small-scale

0.460

High

1282395

POLH
DNA polymerase eta

1

0

Small-scale

0.460

High

338804

EGFR
Epidermal growth factor receptor

1

0

Small-scale

0.458

High

717266

CTNB1
Catenin beta-1

1

0

Small-scale

0.458

High

1245117

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

1282384

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

131269

BIN1
Myc box-dependent-interacting protein 1

1

5

High-throughput

0.457

High

306264

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

2

High-throughput

0.445

High

891265

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

2

High-throughput

0.445

High

1039139

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

1

High-throughput

0.445

High

1282382

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

2

High-throughput

0.445

High

1173024

TM1L2
TOM1-like protein 2

1

2

Small-scale

0.439

High

1267369

F168A
Protein FAM168A

1

0

High-throughput

0.279

Low

1166417

CLC4G
C-type lectin domain family 4 member G

1

0

High-throughput

0.265

Low

678036

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

Small-scale

0.261

Low

1282387

CUED1
CUE domain-containing protein 1

1

0

Small-scale

0.251

Low

1282396

RHBD3
Rhomboid domain-containing protein 3

1

0

Small-scale

0.251

Low

167995

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.249

Low

1282389

SEPT3
Neuronal-specific septin-3

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024