Protein: NFKB2
Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10 protein) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2) (Oncogene Lyt-10) (Lyt10) [Cleaved into: Nuclear factor NF-kappa-B p52 subunit]

Gene: NFKB2
Organism: Homo sapiens
Interactions: 222
UniProt ID: Q00653

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002268 - follicular dendritic cell differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

587527

NFKB1
Nuclear factor NF-kappa-B p105 subunit

15

19

Small-scale

0.984

High

961365

RELB
Transcription factor RelB

14

17

Small-scale

0.981

High

961368

TF65
Transcription factor p65

14

17

Small-scale

0.981

High

961369

REL
Proto-oncogene c-Rel

10

17

Small-scale

0.974

High

639729

IKBA
NF-kappa-B inhibitor alpha

7

19

Small-scale

0.966

High

961425

M3K14
Mitogen-activated protein kinase kinase kinase 14

8

20

Small-scale

0.963

High

595669

BCL3
B-cell lymphoma 3 protein

7

20

Small-scale

0.959

High

167522

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

5

20

Small-scale

0.909

High

961391

IKBB
NF-kappa-B inhibitor beta

4

18

High-throughput

0.895

High

121583

IKBE
NF-kappa-B inhibitor epsilon

3

19

Small-scale

0.860

High

961363

NFKB2
Nuclear factor NF-kappa-B p100 subunit

3

19

Small-scale

0.839

High

961410

IKBD
NF-kappa-B inhibitor delta

2

18

High-throughput

0.811

High

961421

ASB2
Ankyrin repeat and SOCS box protein 2

2

13

High-throughput

0.811

High

783315

M3K8
Mitogen-activated protein kinase kinase kinase 8

2

12

High-throughput

0.802

High

961411

IASPP
RelA-associated inhibitor

2

20

Small-scale

0.789

High

386536

P53
Cellular tumor antigen p53

2

10

Small-scale

0.754

High

961451

FBW1A
F-box/WD repeat-containing protein 1A

8

20

Small-scale

0.750

High

961443

FBW1B
F-box/WD repeat-containing protein 11

6

20

Small-scale

0.733

High

961417

FBXW7
F-box/WD repeat-containing protein 7

6

20

Small-scale

0.724

High

961435

IKBZ
NF-kappa-B inhibitor zeta

1

18

High-throughput

0.698

High

149849

RFXK
DNA-binding protein RFXANK

1

19

High-throughput

0.691

High

961381

BIRC2
Baculoviral IAP repeat-containing protein 2

1

14

Small-scale

0.691

High

961440

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

3

20

High-throughput

0.675

High

961438

DEFI6
Differentially expressed in FDCP 6 homolog

3

20

High-throughput

0.667

High

133980

DDX3X
ATP-dependent RNA helicase DDX3X

1

4

High-throughput

0.665

High

961453

NEMO
NF-kappa-B essential modulator

1

20

High-throughput

0.665

High

961387

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

20

Small-scale

0.653

High

542000

ETS1
Protein C-ets-1

1

9

Small-scale

0.646

High

542738

ETS2
Protein C-ets-2

1

10

Small-scale

0.646

High

456316

LOX5
Polyunsaturated fatty acid 5-lipoxygenase

2

3

High-throughput

0.628

High

961444

PADI3
Protein-arginine deiminase type-3

2

2

High-throughput

0.628

High

158446

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

20

High-throughput

0.618

High

381164

TBB4A
Tubulin beta-4A chain

1

20

High-throughput

0.618

High

428142

TBB5
Tubulin beta chain

1

20

High-throughput

0.618

High

515400

CDK4
Cyclin-dependent kinase 4

1

8

Small-scale

0.618

High

616257

RS3
Small ribosomal subunit protein uS3

1

4

High-throughput

0.618

High

835326

GSK3A
Glycogen synthase kinase-3 alpha

1

14

High-throughput

0.618

High

835664

GSK3B
Glycogen synthase kinase-3 beta

1

14

High-throughput

0.618

High

874830

TERA
Transitional endoplasmic reticulum ATPase

1

6

High-throughput

0.618

High

906812

PRS4
26S proteasome regulatory subunit 4

1

3

High-throughput

0.618

High

906991

PRS8
26S proteasome regulatory subunit 8

1

5

High-throughput

0.618

High

913245

PRS10
26S proteasome regulatory subunit 10B

1

5

High-throughput

0.618

High

944186

PRKDC
DNA-dependent protein kinase catalytic subunit

1

7

High-throughput

0.618

High

960150

CDK6
Cyclin-dependent kinase 6

1

8

Small-scale

0.618

High

961372

DHX9
ATP-dependent RNA helicase A

1

2

High-throughput

0.618

High

961400

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

961401

TBA1A
Tubulin alpha-1A chain

1

20

High-throughput

0.618

High

961432

TBB6
Tubulin beta-6 chain

1

20

High-throughput

0.618

High

961433

TBB2B
Tubulin beta-2B chain

1

20

High-throughput

0.618

High

961437

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

1

10

High-throughput

0.618

High

961439

DDX21
Nucleolar RNA helicase 2

1

9

High-throughput

0.618

High

961442

TBK1
Serine/threonine-protein kinase TBK1

1

20

High-throughput

0.618

High

121736

PSD11
26S proteasome non-ATPase regulatory subunit 11

2

3

Small-scale

0.608

High

961408

TNIP2
TNFAIP3-interacting protein 2

2

5

High-throughput

0.601

High

519171

KCRB
Creatine kinase B-type

1

0

High-throughput

0.586

High

346539

MYC
Myc proto-oncogene protein

2

19

High-throughput

0.584

High

961412

ESR2
Estrogen receptor beta

2

20

High-throughput

0.571

High

122667

MEN1
Menin

1

3

Small-scale

0.561

High

961426

T22D3
TSC22 domain family protein 3

1

4

Small-scale

0.561

High

961376

EPS8
Epidermal growth factor receptor kinase substrate 8

1

10

High-throughput

0.555

High

154344

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

9

Small-scale

0.553

High

518978

PIP
Prolactin-inducible protein

1

2

High-throughput

0.536

High

961399

KLC3
Kinesin light chain 3

1

2

High-throughput

0.536

High

961402

COMD2
COMM domain-containing protein 2

1

3

Small-scale

0.536

High

961406

COMD1
COMM domain-containing protein 1

1

5

Small-scale

0.536

High

961407

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

1

12

High-throughput

0.536

High

961418

EFMT3
EEF1A lysine methyltransferase 3

1

5

High-throughput

0.536

High

961428

NPAS1
Neuronal PAS domain-containing protein 1

1

9

High-throughput

0.536

High

961450

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

1

High-throughput

0.536

High

164857

SC16A
Protein transport protein Sec16A

1

5

High-throughput

0.515

High

776648

STAT3
Signal transducer and activator of transcription 3

1

10

Small-scale

0.515

High

911099

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.515

High

921819

RL30
Large ribosomal subunit protein eL30

1

2

High-throughput

0.515

High

961366

RL6
Large ribosomal subunit protein eL6

1

1

High-throughput

0.515

High

961377

TRAF1
TNF receptor-associated factor 1

1

3

Small-scale

0.515

High

961386

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

172416

NKRF
NF-kappa-B-repressing factor

1

3

Small-scale

0.501

High

377254

GCR
Glucocorticoid receptor

1

20

Small-scale

0.501

High

435045

SP1
Transcription factor Sp1

1

13

Small-scale

0.501

High

961414

REQU
Zinc finger protein ubi-d4

1

17

Small-scale

0.501

High

961422

TCPQM
T-complex protein 1 subunit theta-like 2

1

10

High-throughput

0.489

High

961446

PSG11
Pregnancy-specific beta-1-glycoprotein 11

1

4

High-throughput

0.489

High

162635

XPO1
Exportin-1

1

18

High-throughput

0.479

High

198604

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

2

High-throughput

0.479

High

227186

PRKN
E3 ubiquitin-protein ligase parkin

1

20

High-throughput

0.479

High

238059

PDE8A
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A

1

6

Small-scale

0.479

High

271072

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

13

High-throughput

0.479

High

323693

BAG2
BAG family molecular chaperone regulator 2

1

6

High-throughput

0.479

High

325136

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

4

High-throughput

0.479

High

362380

CRP

1

1

Small-scale

0.479

High

400525

RLA2
Large ribosomal subunit protein P2

1

2

High-throughput

0.479

High

430927

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

6

High-throughput

0.479

High

431746

HS90A
Heat shock protein HSP 90-alpha

1

14

High-throughput

0.479

High

432660

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

5

High-throughput

0.479

High

438079

HS90B
Heat shock protein HSP 90-beta

1

14

High-throughput

0.479

High

450839

F16P1
Fructose-1,6-bisphosphatase 1

1

4

High-throughput

0.479

High

455328

PARP1
Poly [ADP-ribose] polymerase 1

1

12

High-throughput

0.479

High

474996

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

15

High-throughput

0.479

High

475636

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

15

Small-scale

0.479

High

486195

IL8
Interleukin-8

1

15

Small-scale

0.479

High

501980

BIP
Endoplasmic reticulum chaperone BiP

1

20

High-throughput

0.479

High

503906

HSP7C
Heat shock cognate 71 kDa protein

1

20

High-throughput

0.479

High

509933

VDR
Vitamin D3 receptor

1

20

Small-scale

0.479

High

516469

PABP1
Polyadenylate-binding protein 1

1

8

High-throughput

0.479

High

524882

XRCC5
X-ray repair cross-complementing protein 5

1

3

High-throughput

0.479

High

531350

K1C10
Keratin, type I cytoskeletal 10

1

3

High-throughput

0.479

High

551669

DESP
Desmoplakin

1

20

High-throughput

0.479

High

564057

HSP76
Heat shock 70 kDa protein 6

1

20

High-throughput

0.479

High

571702

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

2

High-throughput

0.479

High

575015

RL7
Large ribosomal subunit protein uL30

1

3

High-throughput

0.479

High

582227

NUCL
Nucleolin

1

7

High-throughput

0.479

High

599648

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

16

Small-scale

0.479

High

613417

SFPQ
Splicing factor, proline- and glutamine-rich

1

13

High-throughput

0.479

High

622431

CCND1
G1/S-specific cyclin-D1

1

5

Small-scale

0.479

High

637854

PSA3
Proteasome subunit alpha type-3

1

7

High-throughput

0.479

High

642300

RL13
Large ribosomal subunit protein eL13

1

2

High-throughput

0.479

High

653227

PYR1
Multifunctional protein CAD

1

4

High-throughput

0.479

High

656699

PSB5
Proteasome subunit beta type-5

1

10

High-throughput

0.479

High

672087

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

6

High-throughput

0.479

High

672405

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

6

High-throughput

0.479

High

681408

DNJA1
DnaJ homolog subfamily A member 1

1

10

High-throughput

0.479

High

682773

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

14

High-throughput

0.479

High

707590

H2B1B
Histone H2B type 1-B

1

3

High-throughput

0.479

High

713945

HS71L
Heat shock 70 kDa protein 1-like

1

20

High-throughput

0.479

High

724779

MYH9
Myosin-9

1

4

High-throughput

0.479

High

751580

GRP75
Stress-70 protein, mitochondrial

1

20

High-throughput

0.479

High

758191

CDN1A
Cyclin-dependent kinase inhibitor 1

1

5

Small-scale

0.479

High

779250

CCNF
Cyclin-F

1

9

High-throughput

0.479

High

783013

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

4

High-throughput

0.479

High

788815

RS27
Small ribosomal subunit protein eS27

1

3

High-throughput

0.479

High

793905

MATR3
Matrin-3

1

3

High-throughput

0.479

High

807128

RS5
Small ribosomal subunit protein uS7

1

2

High-throughput

0.479

High

807329

RS10
Small ribosomal subunit protein eS10

1

5

High-throughput

0.479

High

809269

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

10

High-throughput

0.479

High

825924

FAS
Fatty acid synthase

1

1

High-throughput

0.479

High

826624

TCPG
T-complex protein 1 subunit gamma

1

9

High-throughput

0.479

High

846928

SMCA4
Transcription activator BRG1

1

8

High-throughput

0.479

High

849183

PSMD7
26S proteasome non-ATPase regulatory subunit 7

1

5

High-throughput

0.479

High

852875

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

9

High-throughput

0.479

High

867687

SYRC
Arginine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

875945

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

1

High-throughput

0.479

High

880089

SYMC
Methionine--tRNA ligase, cytoplasmic

1

5

High-throughput

0.479

High

881139

CTBP2
C-terminal-binding protein 2

1

6

High-throughput

0.479

High

883972

GEMI4
Gem-associated protein 4

1

1

High-throughput

0.479

High

885229

EPIPL
Epiplakin

1

18

High-throughput

0.479

High

893652

PSA6
Proteasome subunit alpha type-6

1

9

High-throughput

0.479

High

897505

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

1

High-throughput

0.479

High

898276

RS3A
Small ribosomal subunit protein eS1

1

1

High-throughput

0.479

High

907643

RS15A
Small ribosomal subunit protein uS8

1

1

High-throughput

0.479

High

907849

RS16
Small ribosomal subunit protein uS9

1

6

High-throughput

0.479

High

910384

RS14
Small ribosomal subunit protein uS11

1

3

High-throughput

0.479

High

910814

RS18
Small ribosomal subunit protein uS13

1

1

High-throughput

0.479

High

911344

RS11
Small ribosomal subunit protein uS17

1

1

High-throughput

0.479

High

913482

RL7A
Large ribosomal subunit protein eL8

1

2

High-throughput

0.479

High

914927

RS4X
Small ribosomal subunit protein eS4, X isoform

1

1

High-throughput

0.479

High

922969

RL11
Large ribosomal subunit protein uL5

1

3

High-throughput

0.479

High

928063

SUMO1
Small ubiquitin-related modifier 1

1

5

Small-scale

0.479

High

928874

SKP1
S-phase kinase-associated protein 1

1

4

High-throughput

0.479

High

929823

ACTG
Actin, cytoplasmic 2

1

16

High-throughput

0.479

High

942137

GTF2I
General transcription factor II-I

1

1

High-throughput

0.479

High

960743

CLH1
Clathrin heavy chain 1

1

8

High-throughput

0.479

High

961364

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

13

High-throughput

0.479

High

961370

EF1A2
Elongation factor 1-alpha 2

1

5

High-throughput

0.479

High

961371

RL18
Large ribosomal subunit protein eL18

1

2

High-throughput

0.479

High

961374

TF3C1
General transcription factor 3C polypeptide 1

1

1

High-throughput

0.479

High

961375

ILF2
Interleukin enhancer-binding factor 2

1

2

High-throughput

0.479

High

961378

TRAF3
TNF receptor-associated factor 3

1

16

High-throughput

0.479

High

961379

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

2

High-throughput

0.479

High

961380

SKP2
S-phase kinase-associated protein 2

1

4

Small-scale

0.479

High

961382

HDAC1
Histone deacetylase 1

1

20

Small-scale

0.479

High

961383

CUL3
Cullin-3

1

20

High-throughput

0.479

High

961384

CUL4A
Cullin-4A

1

20

High-throughput

0.479

High

961385

CUL4B
Cullin-4B

1

20

High-throughput

0.479

High

961388

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

1

High-throughput

0.479

High

961389

TNIP1
TNFAIP3-interacting protein 1

1

17

High-throughput

0.479

High

961390

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

3

High-throughput

0.479

High

961392

EZH2
Histone-lysine N-methyltransferase EZH2

1

8

Small-scale

0.479

High

961393

FSCN1
Fascin

1

1

High-throughput

0.479

High

961394

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

6

High-throughput

0.479

High

961396

A16L1
Autophagy-related protein 16-1

1

10

High-throughput

0.479

High

961397

PRP8
Pre-mRNA-processing-splicing factor 8

1

1

High-throughput

0.479

High

961403

IFNL1
Interferon lambda-1

1

7

Small-scale

0.479

High

961404

IFNL3
Interferon lambda-3

1

7

Small-scale

0.479

High

961405

CCAR2
Cell cycle and apoptosis regulator protein 2

1

3

High-throughput

0.479

High

961413

TFG
Protein TFG

1

5

High-throughput

0.479

High

961416

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

8

High-throughput

0.479

High

961419

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

6

High-throughput

0.479

High

961424

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

2

High-throughput

0.479

High

961427

CCL19
C-C motif chemokine 19

1

20

Small-scale

0.479

High

961430

MBB1A
Myb-binding protein 1A

1

1

High-throughput

0.479

High

961436

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

16

Small-scale

0.479

High

961441

ZRAN1
Ubiquitin thioesterase ZRANB1

1

19

High-throughput

0.479

High

961445

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

1

High-throughput

0.479

High

961447

Q9UQC1
Heat shock protein 72

1

20

High-throughput

0.479

High

961448

RUVB2
RuvB-like 2

1

10

High-throughput

0.479

High

961449

RUVB1
RuvB-like 1

1

10

High-throughput

0.479

High

961454

ZHX2
Zinc fingers and homeoboxes protein 2

1

4

Small-scale

0.479

High

961415

GSLG1
Golgi apparatus protein 1

1

2

High-throughput

0.470

High

759617

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.458

High

771912

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.458

High

846088

RT29
Small ribosomal subunit protein mS29

1

0

High-throughput

0.458

High

907285

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.458

High

920147

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.458

High

961429

TS101
Tumor susceptibility gene 101 protein

1

0

Small-scale

0.458

High

961431

GCP2
Gamma-tubulin complex component 2

1

0

High-throughput

0.458

High

369415

ESR1
Estrogen receptor

1

20

High-throughput

0.445

High

961452

COMDA
COMM domain-containing protein 10

1

17

Small-scale

0.445

High

127484

RPOM
DNA-directed RNA polymerase, mitochondrial

1

1

High-throughput

0.437

High

224616

TIM8A
Mitochondrial import inner membrane translocase subunit Tim8 A

1

4

High-throughput

0.437

High

393163

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

4

High-throughput

0.437

High

778112

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

4

High-throughput

0.437

High

901456

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

1

High-throughput

0.437

High

961373

LG3BP
Galectin-3-binding protein

1

6

High-throughput

0.437

High

961395

ATD3B
ATPase family AAA domain-containing protein 3B

1

13

High-throughput

0.437

High

961398

FBX42
F-box only protein 42

1

4

High-throughput

0.437

High

961409

RLA0L
Putative ribosomal protein uL10-like

1

3

High-throughput

0.437

High

961434

RFIP5
Rab11 family-interacting protein 5

1

3

High-throughput

0.437

High

961423

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.426

High

738656

TNR3
Tumor necrosis factor receptor superfamily member 3

1

8

Small-scale

0.407

High

961367

UPAR
Urokinase plasminogen activator surface receptor

1

0

Small-scale

0.249

Low

961420

BBC3B
Bcl-2-binding component 3, isoforms 3/4

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024