Protein: DDI2
Protein DDI1 homolog 2 (EC 3.4.23.-)

Gene: DDI2
Organism: Homo sapiens
Interactions: 121
UniProt ID: Q5TDH0

Gene Ontology (top 5):
GO:0004190 - aspartic-type endopeptidase activity
GO:0005654 - nucleoplasm
GO:0005694 - chromosome
GO:0005829 - cytosol
GO:0010498 - proteasomal protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

475888

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

4

20

Small-scale

0.899

High

872275

RD23B
UV excision repair protein RAD23 homolog B

3

19

High-throughput

0.861

High

1136655

NRIP3
Nuclear receptor-interacting protein 3

2

11

High-throughput

0.811

High

130934

PSDE
26S proteasome non-ATPase regulatory subunit 14

2

20

Small-scale

0.754

High

227713

PRKN
E3 ubiquitin-protein ligase parkin

2

20

High-throughput

0.754

High

907059

PRS8
26S proteasome regulatory subunit 8

2

20

Small-scale

0.754

High

1136661

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

2

6

Small-scale

0.754

High

1136633

DDI1
Protein DDI1 homolog 1

1

18

High-throughput

0.691

High

509673

UBL4A
Ubiquitin-like protein 4A

1

20

High-throughput

0.665

High

1136638

H2B1H
Histone H2B type 1-H

1

11

High-throughput

0.665

High

1136644

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

6

High-throughput

0.665

High

983150

UBE3A
Ubiquitin-protein ligase E3A

1

20

Small-scale

0.647

High

203705

SUV91
Histone-lysine N-methyltransferase SUV39H1

2

1

High-throughput

0.628

High

1136639

RN166
E3 ubiquitin-protein ligase RNF166

1

18

High-throughput

0.618

High

572990

PRS6A
26S proteasome regulatory subunit 6A

1

20

High-throughput

0.618

High

730283

PRS7
26S proteasome regulatory subunit 7

1

20

High-throughput

0.618

High

779568

CCNF
Cyclin-F

1

4

High-throughput

0.618

High

798691

PRS6B
26S proteasome regulatory subunit 6B

1

20

High-throughput

0.618

High

803572

BAG6
Large proline-rich protein BAG6

1

18

High-throughput

0.618

High

849216

PSMD7
26S proteasome non-ATPase regulatory subunit 7

1

12

High-throughput

0.618

High

870824

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

5

High-throughput

0.618

High

874117

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

16

High-throughput

0.618

High

882360

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

5

High-throughput

0.618

High

906853

PRS4
26S proteasome regulatory subunit 4

1

20

High-throughput

0.618

High

913291

PRS10
26S proteasome regulatory subunit 10B

1

20

High-throughput

0.618

High

1027692

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

20

High-throughput

0.618

High

1062825

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

18

High-throughput

0.618

High

1081011

ADRM1
Proteasomal ubiquitin receptor ADRM1

1

7

High-throughput

0.618

High

1136623

DDI2
Protein DDI1 homolog 2

1

18

High-throughput

0.618

High

1136625

RN123
E3 ubiquitin-protein ligase RNF123

1

7

High-throughput

0.618

High

1136637

H2A1C
Histone H2A type 1-C

1

8

High-throughput

0.618

High

1136649

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

20

High-throughput

0.618

High

1136656

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.618

High

1136657

UBQL2
Ubiquilin-2

1

18

High-throughput

0.618

High

1025259

NR1H3
Oxysterols receptor LXR-alpha

2

14

High-throughput

0.611

High

1136636

RDH5
Retinol dehydrogenase 5

3

3

High-throughput

0.609

High

1131334

HP1B3
Heterochromatin protein 1-binding protein 3

2

0

High-throughput

0.602

High

637701

PSA2
Proteasome subunit alpha type-2

2

20

Small-scale

0.584

High

656730

PSB5
Proteasome subunit beta type-5

2

20

Small-scale

0.584

High

1136634

ZDHC1
Palmitoyltransferase ZDHHC1

2

6

High-throughput

0.574

High

1136640

PAUF
Pancreatic adenocarcinoma up-regulated factor

2

6

High-throughput

0.574

High

1136642

CPNE2
Copine-2

2

2

High-throughput

0.574

High

1072687

UBE3C
Ubiquitin-protein ligase E3C

1

16

High-throughput

0.553

High

1136628

TRI67
Tripartite motif-containing protein 67

1

19

High-throughput

0.553

High

1063441

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.536

High

535420

GFAP
Glial fibrillary acidic protein

1

3

High-throughput

0.515

High

868539

ATX1
Ataxin-1

1

5

High-throughput

0.515

High

1025782

TADBP
TAR DNA-binding protein 43

1

10

High-throughput

0.515

High

1136629

JAZF1
Juxtaposed with another zinc finger protein 1

1

0

High-throughput

0.513

High

1071603

LRC41
Leucine-rich repeat-containing protein 41

1

0

High-throughput

0.493

High

362590

C1QC
Complement C1q subcomponent subunit C

1

11

High-throughput

0.489

High

1136627

LDH6A
L-lactate dehydrogenase A-like 6A

1

2

High-throughput

0.489

High

1136651

ZN577
Zinc finger protein 577

1

6

High-throughput

0.489

High

1136652

SCMC3
Mitochondrial adenyl nucleotide antiporter SLC25A23

1

3

High-throughput

0.489

High

1136654

MAGF1
Melanoma-associated antigen F1

1

2

High-throughput

0.489

High

121791

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

20

High-throughput

0.479

High

122036

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

18

High-throughput

0.479

High

156308

PSA7
Proteasome subunit alpha type-7

1

20

High-throughput

0.479

High

197323

SERA
D-3-phosphoglycerate dehydrogenase

1

3

High-throughput

0.479

High

198650

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

9

High-throughput

0.479

High

202645

TXNL1
Thioredoxin-like protein 1

1

7

High-throughput

0.479

High

276191

PSD10
26S proteasome non-ATPase regulatory subunit 10

1

4

High-throughput

0.479

High

324446

BAG3
BAG family molecular chaperone regulator 3

1

1

High-throughput

0.479

High

386894

P53
Cellular tumor antigen p53

1

4

High-throughput

0.479

High

431948

HS90A
Heat shock protein HSP 90-alpha

1

5

High-throughput

0.479

High

438256

HS90B
Heat shock protein HSP 90-beta

1

5

High-throughput

0.479

High

495546

THIO
Thioredoxin

1

6

High-throughput

0.479

High

499814

CH60
60 kDa heat shock protein, mitochondrial

1

4

High-throughput

0.479

High

531177

EF2
Elongation factor 2

1

3

High-throughput

0.479

High

594557

PSB1
Proteasome subunit beta type-1

1

20

High-throughput

0.479

High

637447

PSA1
Proteasome subunit alpha type-1

1

20

High-throughput

0.479

High

637913

PSA3
Proteasome subunit alpha type-3

1

20

High-throughput

0.479

High

638146

PSA4
Proteasome subunit alpha type-4

1

20

High-throughput

0.479

High

656249

PSA5
Proteasome subunit alpha type-5

1

20

High-throughput

0.479

High

656483

PSB4
Proteasome subunit beta type-4

1

20

High-throughput

0.479

High

656612

PSB6
Proteasome subunit beta type-6

1

20

High-throughput

0.479

High

770881

TCPZ
T-complex protein 1 subunit zeta

1

7

High-throughput

0.479

High

801712

RAGP1
Ran GTPase-activating protein 1

1

3

High-throughput

0.479

High

819815

PSMD8
26S proteasome non-ATPase regulatory subunit 8

1

8

High-throughput

0.479

High

821254

TCPE
T-complex protein 1 subunit epsilon

1

8

High-throughput

0.479

High

825969

FAS
Fatty acid synthase

1

1

High-throughput

0.479

High

826702

TCPG
T-complex protein 1 subunit gamma

1

8

High-throughput

0.479

High

832005

PSB3
Proteasome subunit beta type-3

1

20

High-throughput

0.479

High

832120

PSB2
Proteasome subunit beta type-2

1

20

High-throughput

0.479

High

842904

TCPQ
T-complex protein 1 subunit theta

1

11

High-throughput

0.479

High

843240

TCPD
T-complex protein 1 subunit delta

1

7

High-throughput

0.479

High

893562

SEM1
26S proteasome complex subunit SEM1

1

6

Small-scale

0.479

High

893686

PSA6
Proteasome subunit alpha type-6

1

20

High-throughput

0.479

High

932741

EF1A1
Elongation factor 1-alpha 1

1

3

High-throughput

0.479

High

943279

TCPB
T-complex protein 1 subunit beta

1

8

High-throughput

0.479

High

1136624

ECM29
Proteasome adapter and scaffold protein ECM29

1

4

High-throughput

0.479

High

1136648

PSB7
Proteasome subunit beta type-7

1

20

High-throughput

0.479

High

1136650

TCPH
T-complex protein 1 subunit eta

1

8

High-throughput

0.479

High

1136659

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

12

High-throughput

0.479

High

1136660

RUVB2
RuvB-like 2

1

3

High-throughput

0.479

High

796756

RANG
Ran-specific GTPase-activating protein

1

0

High-throughput

0.458

High

929306

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.458

High

855986

ZN138
Zinc finger protein 138

1

7

High-throughput

0.445

High

1136635

ZN480
Zinc finger protein 480

1

1

High-throughput

0.445

High

318642

EYA4
Eyes absent homolog 4

1

10

High-throughput

0.437

High

565095

ZNF7
Zinc finger protein 7

1

1

High-throughput

0.407

High

1000222

ZN763
Zinc finger protein 763

1

8

High-throughput

0.407

High

1059442

ZN846
Zinc finger protein 846

1

1

High-throughput

0.407

High

1136626

ZN549
Zinc finger protein 549

1

1

High-throughput

0.407

High

1136630

ZN695
Zinc finger protein 695

1

2

High-throughput

0.407

High

1136643

ZN419
Zinc finger protein 419

1

2

High-throughput

0.407

High

1136646

ZN578
Zinc finger protein 578

1

1

High-throughput

0.407

High

1136647

ZIM3
Zinc finger imprinted 3

1

5

High-throughput

0.407

High

1136658

ZN222
Zinc finger protein 222

1

3

High-throughput

0.407

High

1110154

T10IP
Testis-specific protein 10-interacting protein

1

0

High-throughput

0.279

Low

1110352

FX4L6
Forkhead box protein D4-like 6

1

0

High-throughput

0.279

Low

1136631

CPXCR
CPX chromosomal region candidate gene 1 protein

1

0

High-throughput

0.279

Low

1136641

ELMD3
ELMO domain-containing protein 3

1

0

High-throughput

0.279

Low

1136645

FA81B
Protein FAM81B

1

0

High-throughput

0.279

Low

1136653

CG069
Putative uncharacterized protein PKD1L1-AS1

1

0

High-throughput

0.279

Low

595894

CP2B6
Cytochrome P450 2B6

1

0

High-throughput

0.269

Low

1110386

MOGT2
2-acylglycerol O-acyltransferase 2

1

0

High-throughput

0.269

Low

159373

PLD2
Phospholipase D2

1

0

High-throughput

0.249

Low

1055905

ZN267
Zinc finger protein 267

1

0

High-throughput

0.232

Low

1136632

ZN441
Zinc finger protein 441

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024