Protein: RENT2
Regulator of nonsense transcripts 2 (Up-frameshift suppressor 2 homolog) (hUpf2)

Gene: RENT2, UPF2
Organism: Homo sapiens
Interactions: 135
UniProt ID: Q9HAU5

Gene Ontology (top 5):
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0001889 - liver development
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1272356

RENT1
Regulator of nonsense transcripts 1

23

2

Small-scale

0.991

High

1318130

REN3B
Regulator of nonsense transcripts 3B

12

2

Small-scale

0.980

High

1328746

REN3A
Regulator of nonsense transcripts 3A

5

2

Small-scale

0.922

High

1334889

RENT2
Regulator of nonsense transcripts 2

2

1

Small-scale

0.743

High

1300081

SMG1
Serine/threonine-protein kinase SMG1

5

0

Small-scale

0.694

High

1070647

RNPS1
RNA-binding protein with serine-rich domain 1

4

2

Small-scale

0.692

High

757768

IF4A3
Eukaryotic initiation factor 4A-III

1

1

High-throughput

0.691

High

1334906

RBM8A
RNA-binding protein 8A

5

0

Small-scale

0.688

High

787013

MTREX
Exosome RNA helicase MTR4

1

0

High-throughput

0.622

High

867649

BLM
RecQ-like DNA helicase BLM

1

1

High-throughput

0.621

High

892909

IF4A1
Eukaryotic initiation factor 4A-I

1

1

Small-scale

0.621

High

228744

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

347931

MYC
Myc proto-oncogene protein

2

2

High-throughput

0.584

High

538406

ENPL
Endoplasmin

2

1

High-throughput

0.584

High

966484

EXOSX
Exosome complex component 10

2

0

Small-scale

0.575

High

1215881

DCP2
m7GpppN-mRNA hydrolase

2

0

Small-scale

0.575

High

486833

MYB
Transcriptional activator Myb

1

1

High-throughput

0.561

High

1334898

PUF60
Poly(U)-binding-splicing factor PUF60

1

0

High-throughput

0.549

High

979996

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

0

Small-scale

0.546

High

545909

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

1

High-throughput

0.536

High

896975

ARP2
Actin-related protein 2

1

1

High-throughput

0.536

High

1330001

P63
Tumor protein 63

1

1

Small-scale

0.536

High

1333721

AKTIP
AKT-interacting protein

1

0

High-throughput

0.518

High

470167

H2AZ
Histone H2A.Z

1

0

High-throughput

0.513

High

1295028

CK5P3
CDK5 regulatory subunit-associated protein 3

1

0

High-throughput

0.513

High

1334894

KIF15
Kinesin-like protein KIF15

1

0

High-throughput

0.513

High

1224187

DCP1B
mRNA-decapping enzyme 1B

1

1

High-throughput

0.508

High

1284973

EXOS8
Exosome complex component RRP43

1

1

High-throughput

0.508

High

1326157

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

3

High-throughput

0.508

High

1327521

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.508

High

1334905

EXOS1
Exosome complex component CSL4

1

1

High-throughput

0.508

High

167716

LSM1
U6 snRNA-associated Sm-like protein LSm1

1

0

High-throughput

0.486

High

644328

TTP
mRNA decay activator protein ZFP36

1

0

High-throughput

0.486

High

806179

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.486

High

920079

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.486

High

920557

RS25
Small ribosomal subunit protein eS25

1

0

High-throughput

0.486

High

1305270

PHB2
Prohibitin-2

1

0

High-throughput

0.486

High

1334207

ZN408
Zinc finger protein 408

1

0

High-throughput

0.486

High

1334902

NOB1
RNA-binding protein NOB1

1

0

High-throughput

0.486

High

334291

LDHA
L-lactate dehydrogenase A chain

1

1

High-throughput

0.481

High

944706

MAP1A
Microtubule-associated protein 1A

1

1

High-throughput

0.481

High

1130056

EXOS6
Exosome complex component MTR3

1

2

High-throughput

0.481

High

1334895

NOP53
Ribosome biogenesis protein NOP53

1

1

High-throughput

0.481

High

1334901

CIZ1
Cip1-interacting zinc finger protein

1

1

High-throughput

0.481

High

122234

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

0

Small-scale

0.480

High

163305

XPO1
Exportin-1

1

2

High-throughput

0.479

High

241641

H2B1K
Histone H2B type 1-K

1

1

High-throughput

0.479

High

323165

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

374900

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

379884

MYCN
N-myc proto-oncogene protein

1

2

High-throughput

0.479

High

918702

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

1029892

TIF1B
Transcription intermediary factor 1-beta

1

3

High-throughput

0.479

High

1167984

GGYF2
GRB10-interacting GYF protein 2

1

1

High-throughput

0.479

High

1171775

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

1224416

XRN1
5'-3' exoribonuclease 1

1

1

Small-scale

0.479

High

1331329

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

1334890

EXOS4
Exosome complex component RRP41

1

2

Small-scale

0.479

High

1334891

BRD7
Bromodomain-containing protein 7

1

1

High-throughput

0.479

High

253193

HSF2B
Heat shock factor 2-binding protein

1

0

High-throughput

0.460

High

328962

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.460

High

378773

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.460

High

389597

TYSY
Thymidylate synthase

1

0

High-throughput

0.460

High

403969

ITB1
Integrin beta-1

1

0

High-throughput

0.460

High

408930

K1C18
Keratin, type I cytoskeletal 18

1

0

High-throughput

0.460

High

417423

ENOA
Alpha-enolase

1

0

High-throughput

0.460

High

485294

TZAP
Telomere zinc finger-associated protein

1

0

High-throughput

0.460

High

535940

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.460

High

549133

ZNF44
Zinc finger protein 44

1

0

High-throughput

0.460

High

565038

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.460

High

642608

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.460

High

653731

CALR
Calreticulin

1

0

High-throughput

0.460

High

822812

TNNI2
Troponin I, fast skeletal muscle

1

0

High-throughput

0.460

High

879155

SUMO3
Small ubiquitin-related modifier 3

1

0

High-throughput

0.460

High

905740

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.460

High

916878

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.460

High

923538

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.460

High

941961

PITX1
Pituitary homeobox 1

1

0

High-throughput

0.460

High

951905

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.460

High

1046587

TBB2A
Tubulin beta-2A chain

1

0

High-throughput

0.460

High

1146302

E4F1
Transcription factor E4F1

1

0

High-throughput

0.460

High

1174737

CENPU
Centromere protein U

1

0

High-throughput

0.460

High

1184576

RSRC2
Arginine/serine-rich coiled-coil protein 2

1

0

High-throughput

0.460

High

1234258

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

0

High-throughput

0.460

High

1240999

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.460

High

1270703

REQU
Zinc finger protein ubi-d4

1

0

High-throughput

0.460

High

1289135

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.460

High

1330734

WNK1
Serine/threonine-protein kinase WNK1

1

0

High-throughput

0.460

High

1334892

RM40
Large ribosomal subunit protein mL40

1

0

High-throughput

0.460

High

1334904

RRP7A
Ribosomal RNA-processing protein 7 homolog A

1

0

High-throughput

0.460

High

298804

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

314685

PARN
Poly(A)-specific ribonuclease PARN

1

0

Small-scale

0.458

High

370469

ESR1
Estrogen receptor

1

0

High-throughput

0.458

High

442508

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

484393

SCHI1
Schwannomin-interacting protein 1

1

0

High-throughput

0.458

High

553756

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

652295

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

658438

DPOD1
DNA polymerase delta catalytic subunit

1

0

Small-scale

0.458

High

780130

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

843913

FXR1
RNA-binding protein FXR1

1

0

High-throughput

0.458

High

879344

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

Small-scale

0.458

High

959689

VIGLN
Vigilin

1

0

High-throughput

0.458

High

1046341

EXOS2
Exosome complex component RRP4

1

0

Small-scale

0.458

High

1188886

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1303166

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.458

High

1329091

VP33B
Vacuolar protein sorting-associated protein 33B

1

0

High-throughput

0.458

High

1334893

ANLN
Anillin

1

0

High-throughput

0.458

High

1334897

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1334899

INT6
Integrator complex subunit 6

1

0

Small-scale

0.458

High

1334903

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

402490

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

718211

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.445

High

1245638

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

1

High-throughput

0.445

High

1303763

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.445

High

1334896

ABCF2
ATP-binding cassette sub-family F member 2

1

1

High-throughput

0.439

High

385543

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

321209

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.426

High

1039857

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.426

High

1222847

SRRM1
Serine/arginine repetitive matrix protein 1

1

0

Small-scale

0.426

High

1259996

RAB2B
Ras-related protein Rab-2B

1

0

High-throughput

0.279

Low

306719

NDUA7
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

1

0

High-throughput

0.251

Low

355116

HBAZ
Hemoglobin subunit zeta

1

0

High-throughput

0.251

Low

528186

CY24A
Cytochrome b-245 light chain

1

0

High-throughput

0.251

Low

872102

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

1

0

High-throughput

0.251

Low

1069062

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.251

Low

1202555

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.251

Low

1251173

G45IP
Large ribosomal subunit protein mL64

1

0

High-throughput

0.251

Low

1274317

NAR4
Ecto-ADP-ribosyltransferase 4

1

0

High-throughput

0.251

Low

1307291

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.251

Low

1334907

HS3SA
Heparan sulfate glucosamine 3-O-sulfotransferase 3A1

1

0

High-throughput

0.251

Low

721486

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

824396

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

1315152

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.249

Low

1334900

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

1241626

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024