Protein: MEF2D
Myocyte-specific enhancer factor 2D

Gene: MEF2D
Organism: Homo sapiens
Interactions: 75
UniProt ID: Q14814

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

968779

MEF2A
Myocyte-specific enhancer factor 2A

4

20

Small-scale

0.895

High

968811

MEF2B
Myocyte-specific enhancer factor 2B

2

16

High-throughput

0.811

High

880729

HDAC4
Histone deacetylase 4

5

20

Small-scale

0.713

High

1059584

MK14
Mitogen-activated protein kinase 14

4

14

High-throughput

0.701

High

1059605

CABIN
Calcineurin-binding protein cabin-1

3

2

Small-scale

0.678

High

620154

PAX7
Paired box protein Pax-7

1

4

High-throughput

0.618

High

679107

TLX1
T-cell leukemia homeobox protein 1

1

1

High-throughput

0.618

High

822632

LHX1
LIM/homeobox protein Lhx1

1

3

High-throughput

0.618

High

839743

LHX2
LIM/homeobox protein Lhx2

1

3

High-throughput

0.618

High

1059593

LHX4
LIM/homeobox protein Lhx4

1

3

High-throughput

0.618

High

1059600

LHX3
LIM/homeobox protein Lhx3

1

3

High-throughput

0.618

High

646894

1433T
14-3-3 protein theta

1

4

Small-scale

0.594

High

1026851

MK07
Mitogen-activated protein kinase 7

1

16

Small-scale

0.586

High

998716

EP300
Histone acetyltransferase p300

2

4

Small-scale

0.584

High

1059602

HDAC5
Histone deacetylase 5

2

20

Small-scale

0.576

High

960176

CDK6
Cyclin-dependent kinase 6

1

7

Small-scale

0.569

High

177297

HDAC3
Histone deacetylase 3

1

6

Small-scale

0.561

High

435097

SP1
Transcription factor Sp1

1

6

Small-scale

0.561

High

1031198

SKP2
S-phase kinase-associated protein 2

1

1

Small-scale

0.561

High

1035234

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

1

Small-scale

0.561

High

1059592

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.541

High

158101

TX1B3
Tax1-binding protein 3

1

1

High-throughput

0.536

High

402016

JUN
Transcription factor Jun

1

4

High-throughput

0.536

High

504093

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.536

High

1059595

TCAB1
Telomerase Cajal body protein 1

1

1

High-throughput

0.536

High

153671

ANM5
Protein arginine N-methyltransferase 5

1

2

Small-scale

0.501

High

568672

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

1

Small-scale

0.501

High

681852

AKT1
RAC-alpha serine/threonine-protein kinase

1

2

Small-scale

0.501

High

1059586

CARM1
Histone-arginine methyltransferase CARM1

1

2

Small-scale

0.501

High

1059601

DNM3L
DNA

1

1

Small-scale

0.501

High

840631

ASCL1
Achaete-scute homolog 1

1

4

Small-scale

0.481

High

394722

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

742296

SYUA
Alpha-synuclein

1

0

Small-scale

0.480

High

1059604

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

152647

KMT2D
Histone-lysine N-methyltransferase 2D

1

2

Small-scale

0.479

High

162749

XPO1
Exportin-1

1

1

High-throughput

0.479

High

316886

KLF8
Krueppel-like factor 8

1

5

High-throughput

0.479

High

487437

ANDR
Androgen receptor

1

1

High-throughput

0.479

High

507425

ERG
Transcriptional regulator ERG

1

1

High-throughput

0.479

High

575439

EGR1
Early growth response protein 1

1

1

Small-scale

0.479

High

658503

TEAD1
Transcriptional enhancer factor TEF-1

1

2

High-throughput

0.479

High

727519

HNF1B
Hepatocyte nuclear factor 1-beta

1

4

High-throughput

0.479

High

727870

SOX6
Transcription factor SOX-6

1

5

High-throughput

0.479

High

818055

SOX2
Transcription factor SOX-2

1

4

High-throughput

0.479

High

831331

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.479

High

867871

HIRA
Protein HIRA

1

1

Small-scale

0.479

High

878407

PAX9
Paired box protein Pax-9

1

2

High-throughput

0.479

High

884155

KLF3
Krueppel-like factor 3

1

6

High-throughput

0.479

High

904568

1433G
14-3-3 protein gamma

1

4

High-throughput

0.479

High

905901

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

2

High-throughput

0.479

High

982018

1433F
14-3-3 protein eta

1

4

High-throughput

0.479

High

988762

PAX8
Paired box protein Pax-8

1

3

High-throughput

0.479

High

1038381

HDAC1
Histone deacetylase 1

1

10

Small-scale

0.479

High

1046686

KLF5
Krueppel-like factor 5

1

6

High-throughput

0.479

High

1059589

SP7
Transcription factor Sp7

1

6

High-throughput

0.479

High

1059591

KAT2B
Histone acetyltransferase KAT2B

1

1

Small-scale

0.479

High

1059596

KLF16
Krueppel-like factor 16

1

4

High-throughput

0.479

High

122763

MEN1
Menin

1

0

Small-scale

0.458

High

301819

TRI37
E3 ubiquitin-protein ligase TRIM37

1

0

High-throughput

0.458

High

668689

PML
Protein PML

1

0

High-throughput

0.458

High

986909

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.458

High

1059582

RBBP5
Retinoblastoma-binding protein 5

1

0

Small-scale

0.458

High

1059583

IRF4
Interferon regulatory factor 4

1

0

High-throughput

0.458

High

1059585

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1059587

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1059588

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1059590

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1059594

THOC1
THO complex subunit 1

1

0

High-throughput

0.458

High

1059597

SENP3
Sentrin-specific protease 3

1

0

Small-scale

0.458

High

1059598

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1059599

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

0

Small-scale

0.458

High

1059603

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

791563

HD
Huntingtin

1

0

High-throughput

0.438

High

717832

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.426

High

323759

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024