Protein: CD226
CD226 antigen (DNAX accessory molecule 1) (DNAM-1) (CD antigen CD226)

Gene: CD226
Organism: Homo sapiens
Interactions: 56
UniProt ID: Q15762

Gene Ontology (top 5):
GO:0002729 - positive regulation of natural killer cell cytokine production
GO:0002860 - positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0002891 - positive regulation of immunoglobulin mediated immune response
GO:0005178 - integrin binding
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

545112

PVR
Poliovirus receptor

3

17

Small-scale

0.853

High

1078208

CD226
CD226 antigen

2

20

Small-scale

0.768

High

1078223

NECT2
Nectin-2

2

18

Small-scale

0.768

High

469864

CO4A
Complement C4-A

1

2

High-throughput

0.691

High

591859

RAB4A
Ras-related protein Rab-4A

1

20

High-throughput

0.691

High

783238

TNFL9
Tumor necrosis factor ligand superfamily member 9

1

1

High-throughput

0.691

High

1078218

TTC7B
Tetratricopeptide repeat protein 7B

1

4

High-throughput

0.691

High

1078210

TIGIT
T-cell immunoreceptor with Ig and ITIM domains

1

5

Small-scale

0.665

High

1078216

DUSTY
Dual serine/threonine and tyrosine protein kinase

1

12

High-throughput

0.618

High

1078221

KLH23
Kelch-like protein 23

1

2

High-throughput

0.618

High

1078228

TMX4
Thioredoxin-related transmembrane protein 4

1

9

High-throughput

0.618

High

1078240

KDIS
Kinase D-interacting substrate of 220 kDa

1

6

High-throughput

0.618

High

396635

ITB2
Integrin beta-2

1

6

Small-scale

0.618

High

1078211

Q4LE69
1-phosphatidylinositol 4-kinase

1

3

High-throughput

0.618

High

787649

PI4KA
Phosphatidylinositol 4-kinase alpha

1

8

High-throughput

0.575

High

598481

NF1
Neurofibromin

1

11

High-throughput

0.536

High

871910

AT12A
Potassium-transporting ATPase alpha chain 2

1

6

High-throughput

0.536

High

1034788

TMED1
Transmembrane emp24 domain-containing protein 1

1

2

High-throughput

0.536

High

1051803

EI2BA
Translation initiation factor eIF2B subunit alpha

1

6

High-throughput

0.536

High

1078209

AT2B3
Plasma membrane calcium-transporting ATPase 3

1

10

High-throughput

0.536

High

1078213

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

1

1

High-throughput

0.536

High

1078222

O52N5
Olfactory receptor 52N5

1

2

High-throughput

0.536

High

1078226

CK5P3
CDK5 regulatory subunit-associated protein 3

1

3

High-throughput

0.536

High

1078235

GPC5B
G-protein coupled receptor family C group 5 member B

1

1

High-throughput

0.536

High

1078236

S53A1
Solute carrier family 53 member 1

1

2

High-throughput

0.536

High

565359

TMM11
Transmembrane protein 11, mitochondrial

1

0

High-throughput

0.513

High

1078227

TTYH3
Protein tweety homolog 3

1

0

High-throughput

0.513

High

213826

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.489

High

646605

AOFB
Amine oxidase [flavin-containing] B

1

1

High-throughput

0.489

High

834412

EI2BB
Translation initiation factor eIF2B subunit beta

1

6

High-throughput

0.489

High

835065

TSC2
Tuberin

1

1

High-throughput

0.489

High

1015845

WASC5
WASH complex subunit 5

1

1

High-throughput

0.489

High

1025632

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

4

High-throughput

0.489

High

1038119

ATR
Serine/threonine-protein kinase ATR

1

11

High-throughput

0.489

High

1078217

THADA
tRNA

1

2

High-throughput

0.489

High

1078220

ARL10
ADP-ribosylation factor-like protein 10

1

20

High-throughput

0.489

High

1078225

SGSM3
Small G protein signaling modulator 3

1

6

High-throughput

0.489

High

1078229

ZDHC6
Palmitoyltransferase ZDHHC6

1

3

High-throughput

0.489

High

1078230

AT131
Endoplasmic reticulum transmembrane helix translocase

1

7

High-throughput

0.489

High

1078231

EI2BG
Translation initiation factor eIF2B subunit gamma

1

3

High-throughput

0.489

High

1078232

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

1

High-throughput

0.489

High

1078233

TB22B
TBC1 domain family member 22B

1

5

High-throughput

0.489

High

1078234

INT7
Integrator complex subunit 7

1

1

High-throughput

0.489

High

1078238

EI2BD
Translation initiation factor eIF2B subunit delta

1

6

High-throughput

0.489

High

1078241

YBOX2
Y-box-binding protein 2

1

1

High-throughput

0.489

High

412209

FYN
Tyrosine-protein kinase Fyn

1

19

Small-scale

0.479

High

122785

MEN1
Menin

1

0

High-throughput

0.279

Low

296917

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.279

Low

1078212

TM128
Transmembrane protein 128

1

0

High-throughput

0.279

Low

1078214

IPIL1
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1

1

0

High-throughput

0.279

Low

1078215

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.279

Low

1078219

TM192
Transmembrane protein 192

1

0

High-throughput

0.279

Low

1078224

BSCL2
Seipin

1

0

High-throughput

0.279

Low

1078237

PCYOX
Prenylcysteine oxidase 1

1

0

High-throughput

0.279

Low

1078239

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024