Protein: PELP1
Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of non-genomic activity of estrogen receptor) (Transcription factor HMX3)

Gene: PELP1
Organism: Homo sapiens
Interactions: 169
UniProt ID: Q8IZL8

Gene Ontology (top 5):
GO:0000791 - euchromatin
GO:0003682 - chromatin binding
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1224527

WDR18
WD repeat-containing protein 18

11

14

Small-scale

0.760

High

1224533

SENP3
Sentrin-specific protease 3

7

4

Small-scale

0.751

High

1224542

TEX10
Testis-expressed protein 10

6

1

Small-scale

0.730

High

1224552

LAS1L
Ribosomal biogenesis protein LAS1L

5

2

Small-scale

0.713

High

1132137

NOL9
Polynucleotide 5'-hydroxyl-kinase NOL9

4

1

Small-scale

0.694

High

369973

ESR1
Estrogen receptor

4

20

Small-scale

0.686

High

902664

SUMO2
Small ubiquitin-related modifier 2

4

7

Small-scale

0.683

High

934969

H31
Histone H3.1

3

20

Small-scale

0.678

High

418448

NPM
Nucleophosmin

3

2

Small-scale

0.662

High

952460

H33
Histone H3.3

2

20

Small-scale

0.633

High

387081

P53
Cellular tumor antigen p53

2

19

Small-scale

0.629

High

271360

NPM3
Nucleoplasmin-3

2

2

High-throughput

0.628

High

127317

IPO5
Importin-5

2

6

Small-scale

0.611

High

391789

H2A1B
Histone H2A type 1-B/E

2

14

High-throughput

0.611

High

550853

RS2
Small ribosomal subunit protein uS5

2

1

High-throughput

0.611

High

642449

RL13
Large ribosomal subunit protein eL13

2

1

High-throughput

0.611

High

649602

RL10
Large ribosomal subunit protein uL16

2

1

High-throughput

0.611

High

1085814

IF16
Gamma-interferon-inducible protein 16

2

7

High-throughput

0.611

High

1153869

IFIX
Pyrin and HIN domain-containing protein 1

2

7

High-throughput

0.611

High

232313

KDM1A
Lysine-specific histone demethylase 1A

1

13

Small-scale

0.597

High

523059

SRC
Proto-oncogene tyrosine-protein kinase Src

2

17

Small-scale

0.595

High

917575

H4
Histone H4

2

10

Small-scale

0.595

High

553155

RFA2
Replication protein A 32 kDa subunit

2

7

High-throughput

0.584

High

651656

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

8

High-throughput

0.584

High

720890

RFA3
Replication protein A 14 kDa subunit

2

6

High-throughput

0.584

High

998875

EP300
Histone acetyltransferase p300

2

18

Small-scale

0.584

High

1224539

ANLN
Anillin

2

4

High-throughput

0.584

High

587631

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

10

High-throughput

0.578

High

776740

STAT3
Signal transducer and activator of transcription 3

1

11

Small-scale

0.573

High

414335

RB
Retinoblastoma-associated protein

1

2

Small-scale

0.561

High

1224536

BCAS3
BCAS3 microtubule associated cell migration factor

1

1

Small-scale

0.561

High

272811

TM1L1
TOM1-like protein 1

1

1

High-throughput

0.541

High

803633

BAG6
Large proline-rich protein BAG6

1

14

High-throughput

0.541

High

296524

KPCD3
Serine/threonine-protein kinase D3

1

6

High-throughput

0.536

High

316093

CBX6
Chromobox protein homolog 6

1

15

High-throughput

0.536

High

400992

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.536

High

470454

H2A1
Histone H2A type 1

1

14

High-throughput

0.536

High

472805

H2AB1
Histone H2A-Bbd type 1

1

17

High-throughput

0.536

High

585504

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

11

High-throughput

0.536

High

586847

CSK22
Casein kinase II subunit alpha'

1

13

High-throughput

0.536

High

781772

MNDA
Myeloid cell nuclear differentiation antigen

1

7

High-throughput

0.536

High

796608

KSYK
Tyrosine-protein kinase SYK

1

20

High-throughput

0.536

High

806079

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.536

High

818238

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.536

High

840983

MAP2
Methionine aminopeptidase 2

1

1

High-throughput

0.536

High

929556

RACK1
Small ribosomal subunit protein RACK1

1

11

High-throughput

0.536

High

942789

SRPK2
SRSF protein kinase 2

1

20

High-throughput

0.536

High

1030348

G3BP1
Ras GTPase-activating protein-binding protein 1

1

5

High-throughput

0.536

High

1134171

PHF19
PHD finger protein 19

1

7

High-throughput

0.536

High

1224522

SRPK1
SRSF protein kinase 1

1

18

High-throughput

0.536

High

1224526

RBM4B
RNA-binding protein 4B

1

7

High-throughput

0.536

High

1224538

TF7L2
Transcription factor 7-like 2

1

20

High-throughput

0.536

High

1224546

SRP68
Signal recognition particle subunit SRP68

1

2

High-throughput

0.536

High

1224549

SRPK3
SRSF protein kinase 3

1

16

High-throughput

0.536

High

1224553

NGN3
Neurogenin-3

1

11

High-throughput

0.536

High

1224541

MDN1
Midasin

1

10

Small-scale

0.534

High

160093

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

3

Small-scale

0.523

High

828830

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

1176029

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.513

High

1192985

ZN467
Zinc finger protein 467

1

0

High-throughput

0.513

High

1224519

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.513

High

171415

SMAD9
Mothers against decapentaplegic homolog 9

1

13

High-throughput

0.508

High

1224521

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

8

High-throughput

0.504

High

890740

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

4

High-throughput

0.501

High

971262

H11
Histone H1.1

1

6

Small-scale

0.501

High

1087047

H2A2C
Histone H2A type 2-C

1

14

Small-scale

0.501

High

1087253

H2B2E
Histone H2B type 2-E

1

20

Small-scale

0.501

High

1224514

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

10

High-throughput

0.501

High

363224

FINC
Fibronectin

1

5

High-throughput

0.489

High

1224510

ESR2
Estrogen receptor beta

1

20

High-throughput

0.484

High

122875

MEN1
Menin

1

2

High-throughput

0.479

High

123285

CBX4
E3 SUMO-protein ligase CBX4

1

15

Small-scale

0.479

High

146636

SOCS2
Suppressor of cytokine signaling 2

1

20

Small-scale

0.479

High

149037

CTRO
Citron Rho-interacting kinase

1

8

High-throughput

0.479

High

177937

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.479

High

179717

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

9

High-throughput

0.479

High

244654

BRD4
Bromodomain-containing protein 4

1

11

High-throughput

0.479

High

255919

OBSL1
Obscurin-like protein 1

1

6

High-throughput

0.479

High

298642

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

308878

KI20A
Kinesin-like protein KIF20A

1

13

High-throughput

0.479

High

318669

EYA4
Eyes absent homolog 4

1

16

High-throughput

0.479

High

319915

HERC2
E3 ubiquitin-protein ligase HERC2

1

9

High-throughput

0.479

High

328894

TOP3B
DNA topoisomerase 3-beta-1

1

1

High-throughput

0.479

High

347293

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

377479

GCR
Glucocorticoid receptor

1

20

Small-scale

0.479

High

402235

JUN
Transcription factor Jun

1

20

High-throughput

0.479

High

429914

CATL1
Procathepsin L

1

1

High-throughput

0.479

High

472888

H2AB2
Histone H2A-Bbd type 2/3

1

17

High-throughput

0.479

High

487586

ANDR
Androgen receptor

1

20

Small-scale

0.479

High

504377

HSP7C
Heat shock cognate 71 kDa protein

1

6

High-throughput

0.479

High

555540

H2AX
Histone H2AX

1

14

High-throughput

0.479

High

611465

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

20

Small-scale

0.479

High

668821

PML
Protein PML

1

15

High-throughput

0.479

High

684871

STIP1
Stress-induced-phosphoprotein 1

1

7

High-throughput

0.479

High

708699

MCM5
DNA replication licensing factor MCM5

1

6

High-throughput

0.479

High

760168

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.479

High

779721

CCNF
Cyclin-F

1

8

High-throughput

0.479

High

801913

RECQ1
ATP-dependent DNA helicase Q1

1

16

High-throughput

0.479

High

850112

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

7

High-throughput

0.479

High

864840

MK12
Mitogen-activated protein kinase 12

1

11

Small-scale

0.479

High

868598

ATX1
Ataxin-1

1

3

High-throughput

0.479

High

898670

RL26
Large ribosomal subunit protein uL24

1

1

Small-scale

0.479

High

905525

TSN5
Tetraspanin-5

1

3

Small-scale

0.479

High

908798

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.479

High

916691

RS6
Small ribosomal subunit protein eS6

1

3

High-throughput

0.479

High

941144

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

967272

EWS
RNA-binding protein EWS

1

12

High-throughput

0.479

High

969844

KIF23
Kinesin-like protein KIF23

1

7

High-throughput

0.479

High

1018575

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

9

High-throughput

0.479

High

1035881

BIRC3
Baculoviral IAP repeat-containing protein 3

1

7

High-throughput

0.479

High

1059174

CBX2
Chromobox protein homolog 2

1

15

Small-scale

0.479

High

1061492

CUL7
Cullin-7

1

5

High-throughput

0.479

High

1064476

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.479

High

1071479

ZMY11
Zinc finger MYND domain-containing protein 11

1

15

Small-scale

0.479

High

1080105

EZH2
Histone-lysine N-methyltransferase EZH2

1

17

High-throughput

0.479

High

1170757

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

1220850

PHC2
Polyhomeotic-like protein 2

1

8

Small-scale

0.479

High

1221559

SMC5
Structural maintenance of chromosomes protein 5

1

10

High-throughput

0.479

High

1224504

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

6

High-throughput

0.479

High

1224505

SIR6
NAD-dependent protein deacylase sirtuin-6

1

11

High-throughput

0.479

High

1224507

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.479

High

1224508

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

1224511

HDAC2
Histone deacetylase 2

1

15

Small-scale

0.479

High

1224512

CBP
CREB-binding protein

1

18

Small-scale

0.479

High

1224513

KAT6A
Histone acetyltransferase KAT6A

1

18

High-throughput

0.479

High

1224515

H2B1A
Histone H2B type 1-A

1

20

High-throughput

0.479

High

1224517

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

9

High-throughput

0.479

High

1224523

NELL2
Protein kinase C-binding protein NELL2

1

3

Small-scale

0.479

High

1224524

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.479

High

1224525

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

2

High-throughput

0.479

High

1224529

FACD2
Fanconi anemia group D2 protein

1

2

High-throughput

0.479

High

1224531

FOXQ1
Forkhead box protein Q1

1

13

High-throughput

0.479

High

1224534

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

15

High-throughput

0.479

High

1224535

PKHA4
Pleckstrin homology domain-containing family A member 4

1

10

High-throughput

0.479

High

1224537

ECT2
Protein ECT2

1

4

High-throughput

0.479

High

1224540

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

11

High-throughput

0.479

High

1224545

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

4

High-throughput

0.479

High

1224550

CHTOP
Chromatin target of PRMT1 protein

1

1

Small-scale

0.479

High

1224551

TRAF6
TNF receptor-associated factor 6

1

12

Small-scale

0.479

High

525986

IFM1
Interferon-induced transmembrane protein 1

1

0

High-throughput

0.458

High

1056076

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

1083674

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.458

High

1085313

FSCN1
Fascin

1

0

High-throughput

0.458

High

1224506

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.458

High

1224518

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1224520

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

1224544

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

903360

WDR5
WD repeat-containing protein 5

1

11

Small-scale

0.445

High

1039683

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.445

High

1057536

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

5

High-throughput

0.445

High

1224547

AGO1
Protein argonaute-1

1

1

High-throughput

0.445

High

1139834

OBI1
ORC ubiquitin ligase 1

1

0

High-throughput

0.438

High

385150

NTRK1
High affinity nerve growth factor receptor

1

8

High-throughput

0.437

High

841078

TNF10
Tumor necrosis factor ligand superfamily member 10

1

4

Small-scale

0.437

High

1053602

GRM2
Metabotropic glutamate receptor 2

1

1

High-throughput

0.437

High

1198093

TM11B
Transmembrane protease serine 11B

1

4

High-throughput

0.437

High

1224509

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.437

High

1224516

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.437

High

1224528

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

2

High-throughput

0.437

High

1224532

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

5

Small-scale

0.437

High

1224543

TMOD3
Tropomodulin-3

1

2

Small-scale

0.437

High

1224548

HECD1
E3 ubiquitin-protein ligase HECTD1

1

11

High-throughput

0.437

High

484164

CALM3
Calmodulin-3

1

0

High-throughput

0.426

High

742389

SYUA
Alpha-synuclein

1

1

Small-scale

0.408

High

1224530

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

11

High-throughput

0.407

High

1054850

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

944547

BL1S1
Biogenesis of lysosome-related organelles complex 1 subunit 1

1

0

Small-scale

0.251

Low

377868

TFF1
Trefoil factor 1

1

0

Small-scale

0.249

Low

1022380

IL24
Interleukin-24

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024