Protein: DIM1
Probable dimethyladenosine transferase (EC 2.1.1.183) (DIM1 dimethyladenosine transferase 1 homolog) (DIM1 dimethyladenosine transferase 1-like) (Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase) (Probable 18S rRNA dimethylase) (Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase)

Gene: DIM1, DIMT1
Organism: Homo sapiens
Interactions: 165
UniProt ID: Q9UNQ2

Gene Ontology (top 5):
GO:0000179 - rRNA (adenine-N6,N6-)-dimethyltransferase activity
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

348238

MYC
Myc proto-oncogene protein

3

2

High-throughput

0.656

High

370712

ESR1
Estrogen receptor

3

1

High-throughput

0.633

High

908214

RS16
Small ribosomal subunit protein uS9

2

1

High-throughput

0.611

High

962458

HNRPU
Heterogeneous nuclear ribonucleoprotein U

2

1

High-throughput

0.611

High

1334602

LN28A
Protein lin-28 homolog A

2

2

High-throughput

0.601

High

1312517

THTPA
Thiamine-triphosphatase

2

0

High-throughput

0.585

High

760388

RL3
Large ribosomal subunit protein uL3

2

1

High-throughput

0.584

High

877950

FOXA1
Hepatocyte nuclear factor 3-alpha

2

1

High-throughput

0.584

High

1345586

SLX9
Ribosome biogenesis protein SLX9 homolog

2

0

High-throughput

0.576

High

508267

FGFR1
Fibroblast growth factor receptor 1

2

1

High-throughput

0.571

High

665966

PTN6
Tyrosine-protein phosphatase non-receptor type 6

2

0

High-throughput

0.559

High

1343795

ANLN
Anillin

2

0

High-throughput

0.559

High

489342

H14
Histone H1.4

1

1

High-throughput

0.536

High

649824

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.536

High

759893

RS19
Small ribosomal subunit protein eS19

1

1

High-throughput

0.536

High

922465

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.536

High

929723

RACK1
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.536

High

1047000

BYST
Bystin

1

2

High-throughput

0.536

High

1202184

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

2

High-throughput

0.536

High

1302100

SRPK1
SRSF protein kinase 1

1

1

High-throughput

0.536

High

1313918

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

1

High-throughput

0.536

High

1335792

CBX8
Chromobox protein homolog 8

1

1

High-throughput

0.536

High

1334351

UBP42
Ubiquitin carboxyl-terminal hydrolase 42

1

2

High-throughput

0.515

High

283628

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.513

High

365111

FRIL
Ferritin light chain

1

0

High-throughput

0.513

High

448015

SRP19
Signal recognition particle 19 kDa protein

1

0

High-throughput

0.513

High

739874

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

806222

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

828941

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

850998

HDGF
Hepatoma-derived growth factor

1

0

High-throughput

0.513

High

1033408

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.513

High

1034686

HAP28
28 kDa heat- and acid-stable phosphoprotein

1

0

High-throughput

0.513

High

1273357

IRF7
Interferon regulatory factor 7

1

0

High-throughput

0.513

High

1312094

RBM42
RNA-binding protein 42

1

0

High-throughput

0.513

High

1344734

SMYD2
N-lysine methyltransferase SMYD2

1

0

High-throughput

0.513

High

1355305

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.513

High

1357574

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.513

High

180507

MAGB2
Melanoma-associated antigen B2

1

2

High-throughput

0.489

High

1357573

SRPK3
SRSF protein kinase 3

1

2

High-throughput

0.489

High

396053

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

128343

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

1

High-throughput

0.479

High

149425

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

282749

RNF8
E3 ubiquitin-protein ligase RNF8

1

1

High-throughput

0.479

High

295406

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

298888

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

323307

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

380020

MYCN
N-myc proto-oncogene protein

1

2

High-throughput

0.479

High

442593

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

1

High-throughput

0.479

High

551020

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

570612

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

2

High-throughput

0.479

High

631259

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

749957

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.479

High

870932

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

3

High-throughput

0.479

High

893196

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

898793

RL26
Large ribosomal subunit protein uL24

1

2

High-throughput

0.479

High

907782

RS15A
Small ribosomal subunit protein uS8

1

1

High-throughput

0.479

High

916968

RS6
Small ribosomal subunit protein eS6

1

1

High-throughput

0.479

High

923591

RL8
Large ribosomal subunit protein uL2

1

1

High-throughput

0.479

High

931487

YBOX1
Y-box-binding protein 1

1

2

High-throughput

0.479

High

1019690

ILF2
Interleukin enhancer-binding factor 2

1

1

High-throughput

0.479

High

1020001

ILF3
Interleukin enhancer-binding factor 3

1

2

High-throughput

0.479

High

1030024

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.479

High

1061687

CUL7
Cullin-7

1

1

High-throughput

0.479

High

1064262

TNIP1
TNFAIP3-interacting protein 1

1

3

High-throughput

0.479

High

1072064

PCBP1
Poly(rC)-binding protein 1

1

1

High-throughput

0.479

High

1128560

HABP4
Intracellular hyaluronan-binding protein 4

1

3

High-throughput

0.479

High

1241069

SERB1
SERPINE1 mRNA-binding protein 1

1

3

High-throughput

0.479

High

1270986

KAT6A
Histone acetyltransferase KAT6A

1

1

High-throughput

0.479

High

1287538

AP2M1
AP-2 complex subunit mu

1

1

High-throughput

0.479

High

1294131

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

1310550

RIOK1
Serine/threonine-protein kinase RIO1

1

2

High-throughput

0.479

High

1319130

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

1327671

BRD8
Bromodomain-containing protein 8

1

2

High-throughput

0.479

High

1350124

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

2

High-throughput

0.479

High

1354864

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1357189

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

1357579

MAGD1
Melanoma-associated antigen D1

1

2

High-throughput

0.479

High

1127728

PRC2B
Protein PRRC2B

1

0

High-throughput

0.460

High

123096

MEN1
Menin

1

0

High-throughput

0.458

High

149777

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.458

High

297001

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.458

High

321673

AP2A1
AP-2 complex subunit alpha-1

1

0

High-throughput

0.458

High

324685

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

418796

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

453707

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

524087

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

554055

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

575225

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.458

High

603787

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

643625

PTBP1
Polypyrimidine tract-binding protein 1

1

0

High-throughput

0.458

High

652605

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

717433

CTNB1
Catenin beta-1

1

0

High-throughput

0.458

High

721779

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

780324

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

805488

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

0

High-throughput

0.458

High

806430

RL21
Large ribosomal subunit protein eL21

1

0

High-throughput

0.458

High

818608

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

824533

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

855259

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

0

High-throughput

0.458

High

899406

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.458

High

909329

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

913833

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.458

High

919564

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.458

High

920585

RS25
Small ribosomal subunit protein eS25

1

0

High-throughput

0.458

High

920722

RS26
Small ribosomal subunit protein eS26

1

0

High-throughput

0.458

High

922756

RL10A
Large ribosomal subunit protein uL1

1

0

High-throughput

0.458

High

949587

RL24
Large ribosomal subunit protein eL24

1

0

High-throughput

0.458

High

970067

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

994399

DHX9
ATP-dependent RNA helicase A

1

0

High-throughput

0.458

High

1022235

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.458

High

1026016

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.458

High

1036204

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1042843

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1046201

DX39B
Spliceosome RNA helicase DDX39B

1

0

High-throughput

0.458

High

1064838

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1076309

TRIP4
Activating signal cointegrator 1

1

0

High-throughput

0.458

High

1085722

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

High-throughput

0.458

High

1116622

LARP7
La-related protein 7

1

0

High-throughput

0.458

High

1119672

MIDN
Midnolin

1

0

High-throughput

0.458

High

1125591

DJC21
DnaJ homolog subfamily C member 21

1

0

High-throughput

0.458

High

1136356

RC3H1
Roquin-1

1

0

High-throughput

0.458

High

1156422

ZN746
Zinc finger protein 746

1

0

High-throughput

0.458

High

1201761

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1235706

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

0

High-throughput

0.458

High

1256480

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1266149

DDX1
ATP-dependent RNA helicase DDX1

1

0

High-throughput

0.458

High

1266376

H1X
Histone H1.10

1

0

High-throughput

0.458

High

1267256

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1281476

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

1287757

GASP2
G-protein coupled receptor-associated sorting protein 2

1

0

High-throughput

0.458

High

1290905

TRI11
E3 ubiquitin-protein ligase TRIM11

1

0

Small-scale

0.458

High

1314592

REPI1
Replication initiator 1

1

0

High-throughput

0.458

High

1318552

API5
Apoptosis inhibitor 5

1

0

High-throughput

0.458

High

1326374

DDX24
ATP-dependent RNA helicase DDX24

1

0

High-throughput

0.458

High

1327151

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

1343384

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

1346911

PAPD1
Poly(A) RNA polymerase, mitochondrial

1

0

High-throughput

0.458

High

1347461

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

1357504

CC14A
Dual specificity protein phosphatase CDC14A

1

0

High-throughput

0.458

High

1357576

TR150
Thyroid hormone receptor-associated protein 3

1

0

High-throughput

0.458

High

1357578

RBM8A
RNA-binding protein 8A

1

0

High-throughput

0.458

High

402622

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

164507

TRI66
Tripartite motif-containing protein 66

1

1

High-throughput

0.437

High

738291

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

1

High-throughput

0.437

High

1018201

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

1

High-throughput

0.437

High

1053692

GRM2
Metabotropic glutamate receptor 2

1

1

High-throughput

0.437

High

1172270

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1189044

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

1356995

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

1357577

MAFB
Transcription factor MafB

1

2

High-throughput

0.437

High

1301419

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

1347855

MED29
Mediator of RNA polymerase II transcription subunit 29

1

0

High-throughput

0.426

High

1356714

AGO1
Protein argonaute-1

1

0

High-throughput

0.426

High

831799

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

581889

VCAM1
Vascular cell adhesion protein 1

2

0

High-throughput

0.313

High

363349

FINC
Fibronectin

1

0

High-throughput

0.279

Low

1357575

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

0

High-throughput

0.279

Low

312103

ZBT7A
Zinc finger and BTB domain-containing protein 7A

1

0

Small-scale

0.249

Low

319381

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.249

Low

339136

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.249

Low

520188

BMP4
Bone morphogenetic protein 4

1

0

High-throughput

0.249

Low

530765

ITA4
Integrin alpha-4

1

0

High-throughput

0.249

Low

588831

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

1

0

High-throughput

0.249

Low

1331629

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1134793

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024