Protein: TF3C5
General transcription factor 3C polypeptide 5 (TF3C-epsilon) (Transcription factor IIIC 63 kDa subunit) (TFIIIC 63 kDa subunit) (TFIIIC63) (Transcription factor IIIC subunit epsilon)

Gene: TF3C5, GTF3C5
Organism: Homo sapiens
Interactions: 152
UniProt ID: Q9Y5Q8

Gene Ontology (top 5):
GO:0000127 - transcription factor TFIIIC complex
GO:0000995 - RNA polymerase III general transcription initiation factor activity
GO:0001002 - RNA polymerase III type 1 promoter sequence-specific DNA binding
GO:0001003 - RNA polymerase III type 2 promoter sequence-specific DNA binding
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1281135

TF3C6
General transcription factor 3C polypeptide 6

1

0

Small-scale

0.697

High

603822

FBRL
rRNA 2'-O-methyltransferase fibrillarin

5

0

High-throughput

0.682

High

862004

PLK1
Serine/threonine-protein kinase PLK1

3

0

High-throughput

0.638

High

587089

CSK22
Casein kinase II subunit alpha'

2

1

High-throughput

0.628

High

1378105

TF3C3
General transcription factor 3C polypeptide 3

2

2

High-throughput

0.628

High

1259932

TF3C2
General transcription factor 3C polypeptide 2

3

0

Small-scale

0.613

High

1356541

TF3C4
General transcription factor 3C polypeptide 4

2

0

Small-scale

0.612

High

1042941

CUL3
Cullin-3

2

1

High-throughput

0.611

High

935431

H31
Histone H3.1

2

2

High-throughput

0.584

High

784118

KPCI
Protein kinase C iota type

2

1

High-throughput

0.571

High

348366

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.559

High

875482

TERA
Transitional endoplasmic reticulum ATPase

2

0

High-throughput

0.559

High

210865

TCF21
Transcription factor 21

1

1

High-throughput

0.541

High

877651

FOXG1
Forkhead box protein G1

1

3

High-throughput

0.536

High

934588

CSK21
Casein kinase II subunit alpha

1

1

High-throughput

0.536

High

987023

SUH
Recombining binding protein suppressor of hairless

1

1

High-throughput

0.536

High

1041305

CUL1
Cullin-1

1

1

High-throughput

0.536

High

983950

KPCZ
Protein kinase C zeta type

2

1

High-throughput

0.521

High

542768

ETS2
Protein C-ets-2

1

0

High-throughput

0.513

High

782407

KDM5C
Lysine-specific demethylase 5C

1

0

High-throughput

0.513

High

908244

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

1069581

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.513

High

1070707

RNPS1
RNA-binding protein with serine-rich domain 1

1

0

High-throughput

0.513

High

1073200

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.513

High

1087511

H2B2E
Histone H2B type 2-E

1

0

High-throughput

0.513

High

1088121

UPP1
Uridine phosphorylase 1

1

0

High-throughput

0.513

High

1199122

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

0

High-throughput

0.513

High

1268733

TF3A
Transcription factor IIIA

1

0

High-throughput

0.513

High

1354182

HDAC6
Histone deacetylase 6

1

0

High-throughput

0.513

High

175328

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

890915

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

High-throughput

0.501

High

1355751

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.493

High

208955

FOXS1
Forkhead box protein S1

1

3

High-throughput

0.489

High

1021389

FOXL1
Forkhead box protein L1

1

3

High-throughput

0.489

High

1306887

FOXB1
Forkhead box protein B1

1

4

High-throughput

0.489

High

1318668

FOXQ1
Forkhead box protein Q1

1

4

High-throughput

0.489

High

1356767

PNMA2
Paraneoplastic antigen Ma2

1

1

High-throughput

0.489

High

1270036

ESR2
Estrogen receptor beta

1

1

High-throughput

0.484

High

589945

TBP
TATA-box-binding protein

1

0

Small-scale

0.480

High

1336571

SRA1
Steroid receptor RNA activator 1

1

0

Small-scale

0.480

High

179909

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

1

High-throughput

0.479

High

245137

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

377834

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

456047

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

554168

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

818664

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

826386

CDK8
Cyclin-dependent kinase 8

1

1

High-throughput

0.479

High

828437

CENPA
Histone H3-like centromeric protein A

1

2

High-throughput

0.479

High

903649

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.479

High

952729

H33
Histone H3.3

1

2

High-throughput

0.479

High

999257

EP300
Histone acetyltransferase p300

1

2

Small-scale

0.479

High

1019191

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

1026608

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.479

High

1057039

MDC1
Mediator of DNA damage checkpoint protein 1

1

2

High-throughput

0.479

High

1173294

PAXI1
PAX-interacting protein 1

1

2

High-throughput

0.479

High

1222660

SLX4
Structure-specific endonuclease subunit SLX4

1

1

High-throughput

0.479

High

1273565

TF3B
Transcription factor IIIB 90 kDa subunit

1

2

Small-scale

0.479

High

1281517

FBXW7
F-box/WD repeat-containing protein 7

1

2

High-throughput

0.479

High

1301024

CIC
Protein capicua homolog

1

2

High-throughput

0.479

High

1312900

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

Small-scale

0.479

High

1328327

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

1331270

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

1

High-throughput

0.479

High

123129

MEN1
Menin

1

0

High-throughput

0.458

High

151269

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.458

High

163528

XPO1
Exportin-1

1

0

High-throughput

0.458

High

182972

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

295466

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

442637

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

570232

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

652728

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

719270

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

721895

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

750564

COIL
Coilin

1

0

High-throughput

0.458

High

787616

MTOR
Serine/threonine-protein kinase mTOR

1

0

Small-scale

0.458

High

809060

YAP1
Transcriptional coactivator YAP1

1

0

High-throughput

0.458

High

841369

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.458

High

918217

H4
Histone H4

1

0

High-throughput

0.458

High

931957

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.458

High

1021648

TAF10
Transcription initiation factor TFIID subunit 10

1

0

High-throughput

0.458

High

1030069

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1035301

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

0

High-throughput

0.458

High

1036252

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1078787

SMAD1
Mothers against decapentaplegic homolog 1

1

0

Small-scale

0.458

High

1080528

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1086061

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1256516

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1267303

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1291136

CDCA5
Sororin

1

0

High-throughput

0.458

High

1327176

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

1332828

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1333843

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

1343862

ANLN
Anillin

1

0

High-throughput

0.458

High

1348406

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1348936

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1350148

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

1355016

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

402679

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

1303899

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.445

High

889035

KR103
Keratin-associated protein 10-3

1

1

High-throughput

0.439

High

517564

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.438

High

283069

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

3

High-throughput

0.437

High

685145

STIP1
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.437

High

1016463

TF3C1
General transcription factor 3C polypeptide 1

1

0

Small-scale

0.426

High

1057752

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.426

High

1230082

RPTOR
Regulatory-associated protein of mTOR

1

2

Small-scale

0.408

High

497889

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.407

High

1169454

NBEL2
Neurobeachin-like protein 2

1

2

High-throughput

0.407

High

888635

KR123
Keratin-associated protein 12-3

2

0

High-throughput

0.316

High

229191

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.305

High

1149412

K1C40
Keratin, type I cytoskeletal 40

1

0

High-throughput

0.299

High

1189499

NT2NA
Notch homolog 2 N-terminal-like protein A

1

0

High-throughput

0.299

High

1306303

MDFI
MyoD family inhibitor

1

0

High-throughput

0.299

High

182236

PDPK1
3-phosphoinositide-dependent protein kinase 1

2

0

High-throughput

0.298

High

498385

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

0

High-throughput

0.298

High

551332

ITF2
Transcription factor 4

1

0

High-throughput

0.282

High

276293

CIB2
Calcium and integrin-binding family member 2

1

0

High-throughput

0.279

Low

428524

TBB5
Tubulin beta chain

1

0

High-throughput

0.279

Low

515979

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.279

Low

549137

ZNF44
Zinc finger protein 44

1

0

High-throughput

0.279

Low

549935

PHKG2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

1

0

High-throughput

0.279

Low

555225

CD44
CD44 antigen

1

0

High-throughput

0.279

Low

1129371

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

0

High-throughput

0.279

Low

1159710

PLBL1
Phospholipase B-like 1

1

0

High-throughput

0.279

Low

1231211

KLH34
Kelch-like protein 34

1

0

High-throughput

0.279

Low

1246682

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.279

Low

1282443

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.279

Low

1295082

LOXL4
Lysyl oxidase homolog 4

1

0

High-throughput

0.279

Low

1297925

PPM1M
Protein phosphatase 1M

1

0

High-throughput

0.279

Low

1308574

NIPS1
Protein NipSnap homolog 1

1

0

High-throughput

0.279

Low

1318439

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.279

Low

1334241

ANRA2
Ankyrin repeat family A protein 2

1

0

Small-scale

0.279

Low

1345648

NRBP2
Nuclear receptor-binding protein 2

1

0

High-throughput

0.279

Low

1349261

HPBP1
Hsp70-binding protein 1

1

0

High-throughput

0.279

Low

780399

CCNF
Cyclin-F

1

0

High-throughput

0.269

Low

1356098

DNM3L
DNA

1

0

Small-scale

0.261

Low

298930

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.249

Low

385800

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

441800

CFAH
Complement factor H

1

0

Small-scale

0.249

Low

909404

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

959800

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

1172452

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1174347

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.249

Low

1189117

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1252270

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

1266619

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.249

Low

1294190

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1296977

SNX27
Sorting nexin-27

1

0

High-throughput

0.249

Low

1313561

CP250
Centrosome-associated protein CEP250

1

0

High-throughput

0.249

Low

1330204

TXNIP
Thioredoxin-interacting protein

1

0

Small-scale

0.249

Low

1357038

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

1130782

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.232

Low

1293129

ZN764
Zinc finger protein 764

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024