Protein: SKIL
Ski-like protein (Ski-related oncogene) (Ski-related protein)

Gene: SKIL
Organism: Homo sapiens
Interactions: 122
UniProt ID: P12757

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001669 - acrosomal vesicle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

521362

SMAD2
Mothers against decapentaplegic homolog 2

9

16

Small-scale

0.971

High

521351

SMAD4
Mothers against decapentaplegic homolog 4

8

16

Small-scale

0.968

High

521343

SMAD3
Mothers against decapentaplegic homolog 3

8

16

Small-scale

0.964

High

521207

SKI
Ski oncogene

4

2

Small-scale

0.902

High

261388

NCOR1
Nuclear receptor corepressor 1

3

4

Small-scale

0.674

High

521408

TRI33
E3 ubiquitin-protein ligase TRIM33

4

6

Small-scale

0.672

High

521370

RN111
E3 ubiquitin-protein ligase Arkadia

3

4

Small-scale

0.664

High

521403

VPS28
Vacuolar protein sorting-associated protein 28 homolog

3

1

High-throughput

0.660

High

521323

SKIL
Ski-like protein

1

2

Small-scale

0.647

High

422137

NFL
Neurofilament light polypeptide

2

2

High-throughput

0.628

High

521363

SMAD1
Mothers against decapentaplegic homolog 1

1

16

Small-scale

0.618

High

521330

XPA
DNA repair protein complementing XP-A cells

2

0

High-throughput

0.580

High

521345

DEUP1
Deuterosome assembly protein 1

2

0

High-throughput

0.580

High

521413

NCOR2
Nuclear receptor corepressor 2

1

4

Small-scale

0.573

High

274174

STK16
Serine/threonine-protein kinase 16

1

1

High-throughput

0.573

High

521347

TLE5
TLE family member 5

1

1

High-throughput

0.573

High

368892

ESR1
Estrogen receptor

1

4

Small-scale

0.561

High

204281

MS18B
Protein Mis18-beta

1

0

High-throughput

0.549

High

521393

NXF3
Nuclear RNA export factor 3

1

0

High-throughput

0.549

High

521411

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.549

High

201193

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

1

Small-scale

0.529

High

521336

RS27
Small ribosomal subunit protein eS27

1

0

High-throughput

0.518

High

521344

ZN200
Zinc finger protein 200

1

0

High-throughput

0.518

High

521367

SMUG1
Single-strand selective monofunctional uracil DNA glycosylase

1

0

High-throughput

0.518

High

443291

VIME
Vimentin

1

2

High-throughput

0.515

High

521328

PECA1
Platelet endothelial cell adhesion molecule

1

1

High-throughput

0.515

High

521368

Q548N1
Vacuolar protein sorting-associated protein 28 homolog

1

1

High-throughput

0.515

High

521361

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

1

0

High-throughput

0.513

High

521397

SIAS
Sialic acid synthase

1

0

High-throughput

0.513

High

234179

PEPL
Periplakin

1

3

High-throughput

0.508

High

277909

PIAS1
E3 SUMO-protein ligase PIAS1

1

2

High-throughput

0.508

High

441855

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

2

High-throughput

0.508

High

521340

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.508

High

521346

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

1

High-throughput

0.508

High

521376

HIPK1
Homeodomain-interacting protein kinase 1

1

5

High-throughput

0.508

High

521378

PIAS4
E3 SUMO-protein ligase PIAS4

1

2

High-throughput

0.508

High

521379

ASCC3
Activating signal cointegrator 1 complex subunit 3

1

1

High-throughput

0.508

High

521389

TRI62
E3 ubiquitin-protein ligase TRIM62

1

1

High-throughput

0.508

High

521394

ZBTB3
Zinc finger and BTB domain-containing protein 3

1

1

High-throughput

0.508

High

521396

HEYL
Hairy/enhancer-of-split related with YRPW motif-like protein

1

1

High-throughput

0.508

High

521400

ZMYM2
Zinc finger MYM-type protein 2

1

1

High-throughput

0.508

High

521406

TTF2
Transcription termination factor 2

1

1

High-throughput

0.508

High

521407

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5

1

3

High-throughput

0.508

High

521412

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

1

1

High-throughput

0.508

High

521414

PIAS3
E3 SUMO-protein ligase PIAS3

1

2

High-throughput

0.508

High

234467

DSCAM
Cell adhesion molecule DSCAM

1

2

High-throughput

0.494

High

281522

WFS1
Wolframin

1

0

High-throughput

0.493

High

521374

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

123170

CBX4
E3 SUMO-protein ligase CBX4

1

0

High-throughput

0.486

High

299094

SASH1
SAM and SH3 domain-containing protein 1

1

0

High-throughput

0.486

High

316300

TYDP2
Tyrosyl-DNA phosphodiesterase 2

1

0

High-throughput

0.486

High

489890

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

0

High-throughput

0.486

High

521324

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.486

High

521327

GLNA
Glutamine synthetase

1

0

High-throughput

0.486

High

521331

FBLN1
Fibulin-1

1

0

High-throughput

0.486

High

521332

EF1G
Elongation factor 1-gamma

1

0

High-throughput

0.486

High

521334

PRS7
26S proteasome regulatory subunit 7

1

0

High-throughput

0.486

High

521341

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.486

High

521342

IF4G2
Eukaryotic translation initiation factor 4 gamma 2

1

0

High-throughput

0.486

High

521348

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

0

High-throughput

0.486

High

521353

TDG
G/T mismatch-specific thymine DNA glycosylase

1

0

High-throughput

0.486

High

521359

SNX17
Sorting nexin-17

1

0

High-throughput

0.486

High

521360

SETB1
Histone-lysine N-methyltransferase SETDB1

1

0

High-throughput

0.486

High

521364

ZBTB6
Zinc finger and BTB domain-containing protein 6

1

0

High-throughput

0.486

High

521366

SVEP1
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1

1

0

High-throughput

0.486

High

521369

CAMP1
Calmodulin-regulated spectrin-associated protein 1

1

0

High-throughput

0.486

High

521372

DHX30
ATP-dependent RNA helicase DHX30

1

0

High-throughput

0.486

High

521373

CXXC5
CXXC-type zinc finger protein 5

1

0

High-throughput

0.486

High

521375

THAP5
THAP domain-containing protein 5

1

0

High-throughput

0.486

High

521380

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

0

High-throughput

0.486

High

521383

MORC4
MORC family CW-type zinc finger protein 4

1

0

High-throughput

0.486

High

521387

UIMC1
BRCA1-A complex subunit RAP80

1

0

High-throughput

0.486

High

521399

I36RA
Interleukin-36 receptor antagonist protein

1

0

High-throughput

0.486

High

521401

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

0

High-throughput

0.486

High

521405

FAF1
FAS-associated factor 1

1

0

High-throughput

0.486

High

521409

TRAK1
Trafficking kinesin-binding protein 1

1

0

High-throughput

0.486

High

521357

MVP
Major vault protein

1

2

High-throughput

0.481

High

521385

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

2

High-throughput

0.481

High

170596

AXIN1
Axin-1

1

1

Small-scale

0.479

High

414146

RB
Retinoblastoma-associated protein

1

1

Small-scale

0.479

High

485102

GLI3
Transcriptional activator GLI3

1

3

Small-scale

0.479

High

487087

ANDR
Androgen receptor

1

4

High-throughput

0.479

High

521333

PML
Protein PML

1

6

Small-scale

0.479

High

521335

TGFR1
TGF-beta receptor type-1

1

1

Small-scale

0.479

High

521337

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

4

Small-scale

0.479

High

521339

H4
Histone H4

1

1

High-throughput

0.479

High

521352

HDAC1
Histone deacetylase 1

1

5

Small-scale

0.479

High

521371

ARK2C
E3 ubiquitin-protein ligase ARK2C

1

4

Small-scale

0.479

High

521388

SIN3A
Paired amphipathic helix protein Sin3a

1

1

Small-scale

0.479

High

521390

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

4

Small-scale

0.479

High

521391

ING2
Inhibitor of growth protein 2

1

1

Small-scale

0.479

High

521395

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

4

Small-scale

0.479

High

521404

FZR1
Fizzy-related protein homolog

1

2

Small-scale

0.479

High

521325

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

2

High-throughput

0.470

High

521326

NID1
Nidogen-1

1

2

High-throughput

0.464

High

521349

PAPP1
Pappalysin-1

1

1

High-throughput

0.464

High

521354

NID2
Nidogen-2

1

2

High-throughput

0.464

High

521365

PSG3
Pregnancy-specific beta-1-glycoprotein 3

1

1

High-throughput

0.464

High

521392

ZN106
Zinc finger protein 106

1

1

High-throughput

0.464

High

521329

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

521402

ZMYM5
Zinc finger MYM-type protein 5

1

1

High-throughput

0.457

High

521415

X5D7R7
Major vault protein isoform G

1

2

High-throughput

0.457

High

521355

SPRL1
SPARC-like protein 1

1

2

High-throughput

0.439

High

521398

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

521382

RBCC1
RB1-inducible coiled-coil protein 1

1

3

Small-scale

0.437

High

521350

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.426

High

521381

Q8N4S1
SPARC-like protein 1

1

2

High-throughput

0.417

High

330056

DRC4
Dynein regulatory complex subunit 4

2

0

High-throughput

0.316

High

231441

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.268

Low

195676

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

1

0

High-throughput

0.265

Low

283374

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.265

Low

434333

TPM2
Tropomyosin beta chain

1

0

High-throughput

0.265

Low

441050

CO4A2

1

0

High-throughput

0.265

Low

521338

TFPI2
Tissue factor pathway inhibitor 2

1

0

High-throughput

0.265

Low

521356

KRT81
Keratin, type II cuticular Hb1

1

0

High-throughput

0.265

Low

521358

GOGB1
Golgin subfamily B member 1

1

0

High-throughput

0.265

Low

521377

CHSS2
Chondroitin sulfate synthase 2

1

0

High-throughput

0.265

Low

521384

TSK
Tsukushi

1

0

High-throughput

0.265

Low

521386

P5CR2
Pyrroline-5-carboxylate reductase 2

1

0

High-throughput

0.265

Low

521410

THS7A
Thrombospondin type-1 domain-containing protein 7A [Cleaved into: Thrombospondin type-1 domain-containing protein 7A, soluble form]

1

0

High-throughput

0.265

Low

306384

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024