Protein: MX1
Interferon-induced GTP-binding protein Mx1 (Interferon-induced protein p78) (IFI-78K) (Interferon-regulated resistance GTP-binding protein MxA) (Myxoma resistance protein 1) (Myxovirus resistance protein 1) [Cleaved into: Interferon-induced GTP-binding protein Mx1, N-terminally processed]

Gene: MX1
Organism: Homo sapiens
Interactions: 62
UniProt ID: P20591

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

594231

MX1
Interferon-induced GTP-binding protein Mx1

6

17

Small-scale

0.961

High

594238

SUMO1
Small ubiquitin-related modifier 1

2

3

Small-scale

0.619

High

278223

PIAS2
E3 SUMO-protein ligase PIAS2

2

3

High-throughput

0.606

High

277931

PIAS1
E3 SUMO-protein ligase PIAS1

2

3

Small-scale

0.584

High

594258

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

1

High-throughput

0.573

High

594271

DAXX
Death domain-associated protein 6

2

0

Small-scale

0.559

High

594277

BCS1
Mitochondrial chaperone BCS1

2

9

High-throughput

0.558

High

594240

UBC9
SUMO-conjugating enzyme UBC9

1

2

Small-scale

0.552

High

594265

CB39L
Calcium-binding protein 39-like

1

0

High-throughput

0.549

High

594234

FXR1
RNA-binding protein FXR1

1

4

High-throughput

0.541

High

528530

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.536

High

594236

SIK1
Serine/threonine-protein kinase SIK1

1

1

High-throughput

0.536

High

594278

SSUH2
Protein SSUH2 homolog

1

2

High-throughput

0.536

High

594276

TRPC6
Short transient receptor potential channel 6

1

7

Small-scale

0.529

High

397774

ISG15
Ubiquitin-like protein ISG15

1

9

High-throughput

0.515

High

594245

LG3BP
Galectin-3-binding protein

1

0

High-throughput

0.513

High

594264

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.513

High

394102

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

594252

CR021
UPF0711 protein C18orf21

1

1

High-throughput

0.489

High

123176

CBX4
E3 SUMO-protein ligase CBX4

1

1

Small-scale

0.481

High

209393

PLRG1
Pleiotropic regulator 1

1

3

Small-scale

0.481

High

254649

ZN623
Zinc finger protein 623

1

1

Small-scale

0.481

High

594232

SP100
Nuclear autoantigen Sp-100

1

6

Small-scale

0.481

High

594235

BLM
RecQ-like DNA helicase BLM

1

2

Small-scale

0.481

High

594242

S25A3
Solute carrier family 25 member 3

1

2

Small-scale

0.481

High

594244

ZBT16
Zinc finger and BTB domain-containing protein 16

1

2

Small-scale

0.481

High

594246

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

2

Small-scale

0.481

High

594251

KI26B
Kinesin-like protein KIF26B

1

5

Small-scale

0.481

High

594256

TBA1A
Tubulin alpha-1A chain

1

2

Small-scale

0.481

High

594267

BRD7
Bromodomain-containing protein 7

1

5

Small-scale

0.481

High

594241

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

1

0

Small-scale

0.480

High

453140

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

5

High-throughput

0.479

High

594249

IRF3
Interferon regulatory factor 3

1

1

Small-scale

0.479

High

594259

CGAS
Cyclic GMP-AMP synthase

1

1

High-throughput

0.479

High

594260

ESR2
Estrogen receptor beta

1

5

High-throughput

0.479

High

594261

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

594266

TRPC7
Short transient receptor potential channel 7

1

7

Small-scale

0.479

High

594247

TRPC3
Short transient receptor potential channel 3

1

7

Small-scale

0.470

High

594270

TRPC4
Short transient receptor potential channel 4

1

7

Small-scale

0.470

High

176550

FANCA
Fanconi anemia group A protein

1

0

Small-scale

0.460

High

594243

TF65
Transcription factor p65

1

0

Small-scale

0.460

High

594248

TDG
G/T mismatch-specific thymine DNA glycosylase

1

0

Small-scale

0.460

High

594250

ADRM1
Proteasomal ubiquitin receptor ADRM1

1

0

Small-scale

0.460

High

594254

ZCH12
Zinc finger CCHC domain-containing protein 12

1

0

Small-scale

0.460

High

594257

EPMIP
EPM2A-interacting protein 1

1

0

Small-scale

0.460

High

594263

ZN251
Zinc finger protein 251

1

0

Small-scale

0.460

High

594273

C8AP2
CASP8-associated protein 2

1

0

Small-scale

0.460

High

594279

GMEB1
Glucocorticoid modulatory element-binding protein 1

1

0

Small-scale

0.460

High

594239

DYL1
Dynein light chain 1, cytoplasmic

1

2

High-throughput

0.445

High

594268

LRC4B
Leucine-rich repeat-containing protein 4B

1

1

Small-scale

0.439

High

594269

PSD3
PH and SEC7 domain-containing protein 3

1

1

Small-scale

0.439

High

594272

HMGX4
HMG domain-containing protein 4

1

5

Small-scale

0.439

High

594233

TRPC1
Short transient receptor potential channel 1

1

7

Small-scale

0.437

High

594274

TRPC5
Short transient receptor potential channel 5

1

7

Small-scale

0.437

High

594275

AKP8L
A-kinase anchor protein 8-like

1

0

High-throughput

0.426

High

519750

KCRU
Creatine kinase U-type, mitochondrial

1

4

High-throughput

0.407

High

594253

Q68D27
Uncharacterized protein DKFZp686B20267

1

1

High-throughput

0.407

High

594237

MCCD1
Mitochondrial coiled-coil domain protein 1

2

0

High-throughput

0.316

High

254245

LRP4
Low-density lipoprotein receptor-related protein 4

1

0

High-throughput

0.279

Low

594255

KLH35
Kelch-like protein 35

1

0

Small-scale

0.251

Low

594262

CG025
UPF0415 protein C7orf25

1

0

Small-scale

0.251

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024