Protein: KDM2A
Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A)

Gene: KDM2A
Organism: Homo sapiens
Interactions: 80
UniProt ID: Q9Y2K7

Gene Ontology (top 5):
GO:0003712 - transcription coregulator activity
GO:0005654 - nucleoplasm
GO:0005694 - chromosome
GO:0006303 - double-strand break repair via nonhomologous end joining
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

929126

SKP1
S-phase kinase-associated protein 1

6

20

Small-scale

0.947

High

1029362

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

2

2

High-throughput

0.628

High

331907

NSD2
Histone-lysine N-methyltransferase NSD2

1

7

Small-scale

0.618

High

1042879

CUL3
Cullin-3

1

20

High-throughput

0.618

High

1299595

UHRF2
E3 ubiquitin-protein ligase UHRF2

1

7

Small-scale

0.618

High

918168

H4
Histone H4

2

5

High-throughput

0.611

High

1070812

RBBP5
Retinoblastoma-binding protein 5

2

12

High-throughput

0.611

High

1300226

KI20B
Kinesin-like protein KIF20B

2

5

Small-scale

0.611

High

1270842

CBP
CREB-binding protein

2

13

Small-scale

0.586

High

348287

MYC
Myc proto-oncogene protein

2

8

High-throughput

0.584

High

918780

H2B1C
Histone H2B type 1-C/E/F/G/I

2

11

High-throughput

0.584

High

935393

H31
Histone H3.1

2

20

High-throughput

0.584

High

978945

TF65
Transcription factor p65

1

4

Small-scale

0.578

High

999234

EP300
Histone acetyltransferase p300

1

14

Small-scale

0.578

High

414401

RB
Retinoblastoma-associated protein

1

3

Small-scale

0.561

High

963707

E2F1
Transcription factor E2F1

1

9

Small-scale

0.561

High

345583

FOS
Protein c-Fos

1

5

High-throughput

0.541

High

123348

CBX4
E3 SUMO-protein ligase CBX4

1

13

High-throughput

0.536

High

781492

BCL6
B-cell lymphoma 6 protein

1

2

Small-scale

0.536

High

903622

WDR5
WD repeat-containing protein 5

1

8

High-throughput

0.536

High

949918

CBX1
Chromobox protein homolog 1

1

13

High-throughput

0.536

High

987022

SUH
Recombining binding protein suppressor of hairless

1

2

High-throughput

0.536

High

1087500

H2B2E
Histone H2B type 2-E

1

11

High-throughput

0.536

High

1299019

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

1

High-throughput

0.536

High

1311563

PCGF1
Polycomb group RING finger protein 1

1

20

High-throughput

0.536

High

1318629

DPY30
Protein dpy-30 homolog

1

1

High-throughput

0.536

High

1354089

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

5

High-throughput

0.536

High

1281884

FBX32
F-box only protein 32

1

0

High-throughput

0.518

High

923600

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.513

High

1044742

FHL3
Four and a half LIM domains protein 3

1

0

High-throughput

0.513

High

1237072

HORM2
HORMA domain-containing protein 2

1

0

High-throughput

0.513

High

1266380

H1X
Histone H1.10

1

0

High-throughput

0.513

High

167411

SMAD7
Mothers against decapentaplegic homolog 7

1

3

High-throughput

0.508

High

950334

SMAD3
Mothers against decapentaplegic homolog 3

1

3

High-throughput

0.508

High

1296271

Z512B
Zinc finger protein 512B

1

4

High-throughput

0.508

High

1086360

H31T
Histone H3.1t

1

20

Small-scale

0.501

High

1174697

H32
Histone H3.2

1

20

Small-scale

0.501

High

891450

UB2G2
Ubiquitin-conjugating enzyme E2 G2

1

8

High-throughput

0.494

High

560018

H12
Histone H1.2

1

4

High-throughput

0.489

High

844804

RAB5C
Ras-related protein Rab-5C

1

1

High-throughput

0.489

High

913847

RL7A
Large ribosomal subunit protein eL8

1

1

High-throughput

0.489

High

1316076

RTF2
Replication termination factor 2

1

1

High-throughput

0.489

High

179891

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

5

High-throughput

0.479

High

245112

BRD4
Bromodomain-containing protein 4

1

10

High-throughput

0.479

High

261044

H2AY
Core histone macro-H2A.1

1

6

High-throughput

0.479

High

268340

EED
Polycomb protein EED

1

9

High-throughput

0.479

High

360556

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.479

High

370756

ESR1
Estrogen receptor

1

20

Small-scale

0.479

High

456013

PARP1
Poly [ADP-ribose] polymerase 1

1

7

High-throughput

0.479

High

555700

H2AX
Histone H2AX

1

6

High-throughput

0.479

High

622551

CCND1
G1/S-specific cyclin-D1

1

11

Small-scale

0.479

High

809042

YAP1
Transcriptional coactivator YAP1

1

19

High-throughput

0.479

High

828427

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.479

High

869561

ATN1
Atrophin-1

1

5

Small-scale

0.479

High

952712

H33
Histone H3.3

1

20

High-throughput

0.479

High

1019182

TP53B
TP53-binding protein 1

1

1

Small-scale

0.479

High

1027339

CBX3
Chromobox protein homolog 3

1

13

High-throughput

0.479

High

1031647

ATM
Serine-protein kinase ATM

1

4

Small-scale

0.479

High

1139473

ECM29
Proteasome adapter and scaffold protein ECM29

1

4

Small-scale

0.479

High

1172342

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.479

High

1193211

SLN11
Schlafen family member 11

1

1

High-throughput

0.479

High

1244578

NUP43
Nucleoporin Nup43

1

16

High-throughput

0.479

High

1269974

ESR2
Estrogen receptor beta

1

19

High-throughput

0.479

High

1288397

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

8

High-throughput

0.479

High

1355798

KLF15
Krueppel-like factor 15

1

12

High-throughput

0.479

High

1377301

ZN330
Zinc finger protein 330

1

4

High-throughput

0.479

High

233697

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

666435

3MG
DNA-3-methyladenine glycosylase

1

0

Small-scale

0.458

High

983275

UBE3A
Ubiquitin-protein ligase E3A

1

12

High-throughput

0.445

High

149444

CTRO
Citron Rho-interacting kinase

1

5

High-throughput

0.437

High

323333

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.437

High

808329

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

13

Small-scale

0.437

High

1025605

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

2

High-throughput

0.437

High

1156014

CGB2
Choriogonadotropin subunit beta variant 2

2

0

High-throughput

0.288

High

417458

ENOA
Alpha-enolase

1

0

High-throughput

0.282

High

400701

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.279

Low

961884

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.279

Low

1054232

BECN1
Beclin-1

1

0

Small-scale

0.249

Low

1134090

DCA12
DDB1- and CUL4-associated factor 12

1

0

High-throughput

0.249

Low

1022637

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024