Protein: PTN5
Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Neural-specific protein-tyrosine phosphatase) (Striatum-enriched protein-tyrosine phosphatase) (STEP)

Gene: PTN5, PTPN5
Organism: Homo sapiens
Interactions: 79
UniProt ID: P54829

Gene Ontology (top 5):
GO:0001784 - phosphotyrosine residue binding
GO:0004725 - protein tyrosine phosphatase activity
GO:0005654 - nucleoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

647525

MK03
Mitogen-activated protein kinase 3

5

20

Small-scale

0.720

High

658867

MK01
Mitogen-activated protein kinase 1

5

20

Small-scale

0.720

High

815961

ATPO
ATP synthase subunit O, mitochondrial

3

1

High-throughput

0.656

High

873129

MK14
Mitogen-activated protein kinase 14

3

20

High-throughput

0.656

High

873156

MOB1A
MOB kinase activator 1A

2

6

High-throughput

0.646

High

873166

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

2

1

High-throughput

0.628

High

412106

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.618

High

873120

PTN5
Tyrosine-protein phosphatase non-receptor type 5

1

19

High-throughput

0.618

High

415273

ATPB
ATP synthase subunit beta, mitochondrial

2

1

High-throughput

0.611

High

873158

RTN4
Reticulon-4

2

2

High-throughput

0.611

High

873137

CLC4G
C-type lectin domain family 4 member G

2

8

High-throughput

0.606

High

623233

AT5F1
ATP synthase F(0) complex subunit B1, mitochondrial

2

0

High-throughput

0.585

High

873154

GHITM
Growth hormone-inducible transmembrane protein

2

0

High-throughput

0.585

High

873163

VAPA
Vesicle-associated membrane protein-associated protein A

2

2

High-throughput

0.584

High

147998

C56D2
Transmembrane reductase CYB561D2

2

0

High-throughput

0.580

High

260260

ENTP3
Ectonucleoside triphosphate diphosphohydrolase 3

2

0

High-throughput

0.580

High

873124

S35B1
Solute carrier family 35 member B1

2

0

High-throughput

0.580

High

873160

MARH5
E3 ubiquitin-protein ligase MARCHF5

2

0

High-throughput

0.580

High

873159

TMM51
Transmembrane protein 51

1

2

High-throughput

0.573

High

226972

PRKN
E3 ubiquitin-protein ligase parkin

1

5

Small-scale

0.561

High

873136

S27A4
Long-chain fatty acid transport protein 4

2

0

High-throughput

0.559

High

873157

S61A2
Protein transport protein Sec61 subunit alpha isoform 2

2

3

High-throughput

0.558

High

873126

CXCL9
C-X-C motif chemokine 9

1

0

High-throughput

0.549

High

869583

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.543

High

307888

SNX4
Sorting nexin-4

1

1

High-throughput

0.541

High

873147

CUL5
Cullin-5

1

3

High-throughput

0.541

High

123550

PGRC1
Membrane-associated progesterone receptor component 1

1

4

High-throughput

0.536

High

297044

TOM70
Mitochondrial import receptor subunit TOM70

1

4

High-throughput

0.536

High

382366

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

5

High-throughput

0.536

High

390798

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.536

High

873134

A20A1
Ankyrin repeat domain-containing protein 20A1

1

9

High-throughput

0.536

High

873135

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

1

3

High-throughput

0.536

High

873140

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.536

High

873144

MSPD2
Motile sperm domain-containing protein 2

1

3

High-throughput

0.536

High

873145

DCAKD
Dephospho-CoA kinase domain-containing protein

1

1

High-throughput

0.536

High

873149

CERS2
Ceramide synthase 2

1

6

High-throughput

0.536

High

873153

DUS15
Dual specificity protein phosphatase 15

1

4

High-throughput

0.536

High

873155

REEP4
Receptor expression-enhancing protein 4

1

2

High-throughput

0.536

High

873151

Q9BSA0
TMEM51 protein

1

2

High-throughput

0.515

High

361330

APOA1
Apolipoprotein A-I

1

0

High-throughput

0.513

High

390143

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.513

High

735897

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.513

High

873125

MEF2A
Myocyte-specific enhancer factor 2A

1

0

High-throughput

0.513

High

873131

CDKN3
Cyclin-dependent kinase inhibitor 3

1

0

High-throughput

0.513

High

873132

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

1

0

High-throughput

0.513

High

873146

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

0

High-throughput

0.513

High

873161

UBIP1
Upstream-binding protein 1

1

0

High-throughput

0.513

High

873164

IKBL1
NF-kappa-B inhibitor-like protein 1

1

0

High-throughput

0.513

High

166161

ZBTB5
Zinc finger and BTB domain-containing protein 5

1

2

High-throughput

0.494

High

873141

CCNQ
Cyclin-Q

1

1

High-throughput

0.494

High

873139

ZN547
Zinc finger protein 547

1

1

High-throughput

0.489

High

160461

AURKA
Aurora kinase A

1

4

High-throughput

0.479

High

310572

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

2

High-throughput

0.479

High

475527

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

Small-scale

0.479

High

776086

ARL1
ADP-ribosylation factor-like protein 1

1

4

High-throughput

0.479

High

854227

DGKE
Diacylglycerol kinase epsilon

1

1

High-throughput

0.479

High

873121

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

3

High-throughput

0.479

High

873122

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

1

High-throughput

0.479

High

873123

DLG4
Disks large homolog 4

1

9

Small-scale

0.479

High

873128

MK11
Mitogen-activated protein kinase 11

1

20

High-throughput

0.479

High

873130

MAPK3
MAP kinase-activated protein kinase 3

1

7

High-throughput

0.479

High

873138

5MP2
eIF5-mimic protein 2

1

1

High-throughput

0.479

High

873167

TBL2
Transducin beta-like protein 2

1

2

High-throughput

0.479

High

174198

SPTC2
Serine palmitoyltransferase 2

1

0

High-throughput

0.458

High

873127

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.458

High

873152

ALG1
Chitobiosyldiphosphodolichol beta-mannosyltransferase

1

0

High-throughput

0.458

High

873162

HACD3
Very-long-chain

1

0

High-throughput

0.458

High

873165

DHCR7
7-dehydrocholesterol reductase

1

0

High-throughput

0.458

High

873168

MTCH2
Mitochondrial carrier homolog 2

1

0

High-throughput

0.458

High

496642

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.445

High

873142

TXND5
Thioredoxin domain-containing protein 5

1

15

High-throughput

0.437

High

873143

MISSL
MAPK-interacting and spindle-stabilizing protein-like

1

3

High-throughput

0.437

High

279104

ATP5H
ATP synthase subunit d, mitochondrial

2

0

High-throughput

0.318

High

873133

TM201
Transmembrane protein 201

2

0

High-throughput

0.316

High

873148

FAF2
FAS-associated factor 2

2

0

High-throughput

0.305

High

241217

TBX19
T-box transcription factor TBX19

1

0

High-throughput

0.279

Low

403485

AT5G1
ATP synthase F(0) complex subunit C1, mitochondrial

1

0

High-throughput

0.279

Low

873150

A7L3B
Ataxin-7-like protein 3B

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024