Protein: SC6A3
Sodium-dependent dopamine transporter (DA transporter) (DAT) (Solute carrier family 6 member 3)

Gene: SC6A3, SLC6A3
Organism: Homo sapiens
Interactions: 25
UniProt ID: Q01959

Gene Ontology (top 5):
GO:0002020 - protease binding
GO:0005102 - signaling receptor binding
GO:0005326 - neurotransmitter transmembrane transporter activity
GO:0005330 - dopamine:sodium symporter activity
GO:0005334 - norepinephrine:sodium symporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

742227

SYUA
Alpha-synuclein

6

6

Small-scale

0.729

High

968115

STX1A
Syntaxin-1A

2

15

Small-scale

0.624

High

808100

NEDD4
E3 ubiquitin-protein ligase NEDD4

2

1

Small-scale

0.595

High

968116

WLS
Protein wntless homolog

2

0

Small-scale

0.585

High

968119

PICK1
PRKCA-binding protein

1

4

Small-scale

0.582

High

815861

MTR1A
Melatonin receptor type 1A

1

4

High-throughput

0.541

High

213265

SNG3
Synaptogyrin-3

1

0

Small-scale

0.537

High

968113

SNTA1
Alpha-1-syntrophin

1

16

Small-scale

0.527

High

200172

TGFI1
Transforming growth factor beta-1-induced transcript 1 protein

1

1

Small-scale

0.527

High

176016

GPR37
Prosaposin receptor GPR37

1

4

Small-scale

0.515

High

537278

DRD2
D(2) dopamine receptor

1

3

Small-scale

0.515

High

123573

PGRC1
Membrane-associated progesterone receptor component 1

1

2

Small-scale

0.479

High

170841

PGRC2
Membrane-associated progesterone receptor component 2

1

2

Small-scale

0.479

High

227205

PRKN
E3 ubiquitin-protein ligase parkin

1

3

Small-scale

0.479

High

437335

4F2
Amino acid transporter heavy chain SLC3A2

1

2

Small-scale

0.479

High

787898

EPS15
Epidermal growth factor receptor substrate 15

1

4

Small-scale

0.479

High

968112

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

3

High-throughput

0.479

High

968114

CUL1
Cullin-1

1

1

Small-scale

0.479

High

968120

FBXL2
F-box/LRR-repeat protein 2

1

1

Small-scale

0.479

High

968121

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

2

Small-scale

0.479

High

968122

EPN1
Epsin-1

1

1

Small-scale

0.479

High

933174

TBA1B
Tubulin alpha-1B chain

1

0

Small-scale

0.458

High

968111

VMAT2
Synaptic vesicular amine transporter

1

0

Small-scale

0.458

High

968118

TBB1
Tubulin beta-1 chain

1

0

Small-scale

0.458

High

968117

RIT2
GTP-binding protein Rit2

1

16

Small-scale

0.457

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024