Protein: JHD2C
Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TR-interacting protein 8) (TRIP-8)

Gene: JHD2C, JMJD1C
Organism: Homo sapiens
Interactions: 74
UniProt ID: Q15652

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0000785 - chromatin
GO:0003712 - transcription coregulator activity
GO:0005654 - nucleoplasm
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

487469

ANDR
Androgen receptor

3

10

Small-scale

0.661

High

1076350

PF21A
PHD finger protein 21A

1

0

High-throughput

0.586

High

986916

SUH
Recombining binding protein suppressor of hairless

2

0

High-throughput

0.585

High

346875

MYC
Myc proto-oncogene protein

2

2

High-throughput

0.584

High

934800

H31
Histone H3.1

2

7

High-throughput

0.584

High

282661

RNF8
E3 ubiquitin-protein ligase RNF8

1

3

Small-scale

0.578

High

740533

PPARG
Peroxisome proliferator-activated receptor gamma

2

10

Small-scale

0.571

High

377349

GCR
Glucocorticoid receptor

2

11

Small-scale

0.563

High

949790

CBX1
Chromobox protein homolog 1

1

5

High-throughput

0.536

High

1076334

H2B2E
Histone H2B type 2-E

1

1

High-throughput

0.536

High

426650

H10
Histone H1.0

1

0

High-throughput

0.513

High

470032

H2AZ
Histone H2A.Z

1

0

High-throughput

0.513

High

1076342

RN168
E3 ubiquitin-protein ligase RNF168

1

0

Small-scale

0.505

High

942682

SRPK2
SRSF protein kinase 2

1

1

High-throughput

0.501

High

1076348

ESR2
Estrogen receptor beta

1

10

Small-scale

0.501

High

858107

NKX25
Homeobox protein Nkx-2.5

1

1

High-throughput

0.500

High

311552

SMC2
Structural maintenance of chromosomes protein 2

1

0

High-throughput

0.493

High

214941

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.486

High

365274

MT2
Metallothionein-2

1

0

High-throughput

0.486

High

622949

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

0

High-throughput

0.486

High

906836

PRS4
26S proteasome regulatory subunit 4

1

0

High-throughput

0.486

High

123951

SPT5H
Transcription elongation factor SPT5

1

1

High-throughput

0.479

High

318625

EYA4
Eyes absent homolog 4

1

1

High-throughput

0.479

High

552816

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

651299

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

668713

PML
Protein PML

1

2

High-throughput

0.479

High

720552

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

808639

YAP1
Transcriptional coactivator YAP1

1

4

High-throughput

0.479

High

818083

SOX2
Transcription factor SOX-2

1

1

Small-scale

0.479

High

831358

CEBPA
CCAAT/enhancer-binding protein alpha

1

3

High-throughput

0.479

High

918385

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

952360

H33
Histone H3.3

1

7

High-throughput

0.479

High

1018968

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

1038407

HDAC1
Histone deacetylase 1

1

7

High-throughput

0.479

High

1056842

MDC1
Mediator of DNA damage checkpoint protein 1

1

1

Small-scale

0.479

High

1076338

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

1076341

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

1076343

NUP43
Nucleoporin Nup43

1

2

High-throughput

0.479

High

1076349

HDAC2
Histone deacetylase 2

1

7

High-throughput

0.479

High

1076351

SOX7
Transcription factor SOX-7

1

1

High-throughput

0.479

High

1076352

DDA1
DET1- and DDB1-associated protein 1

1

1

High-throughput

0.479

High

1076353

WWTR1
WW domain-containing transcription regulator protein 1

1

4

High-throughput

0.479

High

1076355

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

1076358

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

232893

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

0

High-throughput

0.458

High

253981

MTG16
Protein CBFA2T3

1

0

Small-scale

0.458

High

314643

PARN
Poly(A)-specific ribonuclease PARN

1

0

High-throughput

0.458

High

523784

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

771980

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

884159

KLF3
Krueppel-like factor 3

1

0

High-throughput

0.458

High

917331

H4
Histone H4

1

0

High-throughput

0.458

High

940944

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1076335

RNF43
E3 ubiquitin-protein ligase RNF43

1

0

High-throughput

0.458

High

1076337

BCOR
BCL-6 corepressor

1

0

Small-scale

0.458

High

1076339

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

0

High-throughput

0.458

High

1076340

THOC4
THO complex subunit 4

1

0

High-throughput

0.458

High

1076344

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1076357

CNOT2
CCR4-NOT transcription complex subunit 2

1

0

High-throughput

0.458

High

1076359

RCOR1
REST corepressor 1

1

0

High-throughput

0.458

High

301828

TRI37
E3 ubiquitin-protein ligase TRIM37

1

3

High-throughput

0.437

High

994894

GOGA2
Golgin subfamily A member 2

1

1

High-throughput

0.437

High

1076356

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

1

High-throughput

0.437

High

620500

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

0

Small-scale

0.426

High

869996

MYOM2
Myomesin-2

1

0

High-throughput

0.282

High

1070063

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

1

0

High-throughput

0.279

Low

378700

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.265

Low

390251

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.249

Low

685693

PRDX2
Peroxiredoxin-2

1

0

High-throughput

0.249

Low

779478

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

1076336

FBX38
F-box only protein 38

1

0

High-throughput

0.249

Low

1076345

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.249

Low

1076346

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.249

Low

1076347

CNOT9
CCR4-NOT transcription complex subunit 9

1

0

High-throughput

0.249

Low

1076354

TXNIP
Thioredoxin-interacting protein

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024