Protein: MD1L1
Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1) (Mitotic checkpoint MAD1 protein homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181)

Gene: MD1L1, MAD1L1
Organism: Homo sapiens
Interactions: 119
UniProt ID: Q9Y6D9

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000922 - spindle pole
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1029368

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

28

5

Small-scale

0.994

High

1378203

MD1L1
Mitotic spindle assembly checkpoint protein MAD1

3

19

Small-scale

0.878

High

451336

TPM1
Tropomyosin alpha-1 chain

8

20

High-throughput

0.757

High

1356707

BAG5
BAG family molecular chaperone regulator 5

7

2

High-throughput

0.752

High

419092

TPM3
Tropomyosin alpha-3 chain

5

20

High-throughput

0.728

High

282758

RNF8
E3 ubiquitin-protein ligase RNF8

4

10

High-throughput

0.698

High

1254542

CCHCR
Coiled-coil alpha-helical rod protein 1

4

15

High-throughput

0.698

High

456373

LOX5
Polyunsaturated fatty acid 5-lipoxygenase

4

0

High-throughput

0.679

High

875776

MFAP1
Microfibrillar-associated protein 1

3

1

High-throughput

0.675

High

1377852

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

3

13

High-throughput

0.675

High

203576

KCAB3
Voltage-gated potassium channel subunit beta-3

3

2

High-throughput

0.667

High

1377004

CLC11
C-type lectin domain family 11 member A

3

6

High-throughput

0.667

High

518940

TPR
Nucleoprotein TPR

3

19

Small-scale

0.665

High

1304686

T22D3
TSC22 domain family protein 3

3

0

High-throughput

0.646

High

1048834

TRI29
Tripartite motif-containing protein 29

4

5

High-throughput

0.644

High

282376

NEBL
Nebulette

4

13

High-throughput

0.637

High

505027

HSP7C
Heat shock cognate 71 kDa protein

2

10

High-throughput

0.628

High

1157639

CAVN1
Caveolae-associated protein 1

2

2

High-throughput

0.628

High

1062979

MD2BP
MAD2L1-binding protein

3

0

Small-scale

0.622

High

1114422

LEGL
Galectin-related protein

3

6

High-throughput

0.616

High

538632

CCNB1
G2/mitotic-specific cyclin-B1

2

1

Small-scale

0.611

High

638598

RBTN1
Rhombotin-1

2

4

High-throughput

0.606

High

989738

CDK18
Cyclin-dependent kinase 18

2

18

High-throughput

0.606

High

1102827

CCD57
Coiled-coil domain-containing protein 57

2

17

High-throughput

0.606

High

1134962

SYT6
Synaptotagmin-6

2

4

High-throughput

0.606

High

1157471

PPR18
Phostensin

2

11

High-throughput

0.606

High

1251501

LMO3
LIM domain only protein 3

2

4

High-throughput

0.606

High

1252573

LNX1
E3 ubiquitin-protein ligase LNX

2

11

High-throughput

0.606

High

1318470

TSG10
Testis-specific gene 10 protein

2

18

High-throughput

0.606

High

1328921

ATG5
Autophagy protein 5

2

2

High-throughput

0.606

High

1334791

KIF9
Kinesin-like protein KIF9

2

9

High-throughput

0.606

High

245143

BRD4
Bromodomain-containing protein 4

2

9

High-throughput

0.584

High

1017477

CDC20
Cell division cycle protein 20 homolog

2

16

Small-scale

0.584

High

330152

DRC4
Dynein regulatory complex subunit 4

2

0

High-throughput

0.580

High

1083071

CDC37
Hsp90 co-chaperone Cdc37

2

0

High-throughput

0.580

High

1253326

MIEAP
Mitochondria-eating protein

2

0

High-throughput

0.580

High

1272880

GPKOW
G-patch domain and KOW motifs-containing protein

2

0

High-throughput

0.580

High

1293332

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

1378204

CAN7
Calpain-7

2

0

High-throughput

0.580

High

528145

BMP1
Bone morphogenetic protein 1

2

3

High-throughput

0.574

High

1233777

PTGR3
Prostaglandin reductase 3

2

3

High-throughput

0.574

High

637623

PSA1
Proteasome subunit alpha type-1

1

1

High-throughput

0.573

High

1144463

TSH3
Teashirt homolog 3

1

9

High-throughput

0.573

High

1347845

ZSC32
Zinc finger and SCAN domain-containing protein 32

1

5

High-throughput

0.573

High

969622

CENPE
Centromere-associated protein E

1

2

Small-scale

0.569

High

669114

PML
Protein PML

1

9

Small-scale

0.561

High

1262637

LMO7
LIM domain only protein 7

1

19

Small-scale

0.561

High

124138

SPT5H
Transcription elongation factor SPT5

1

5

High-throughput

0.560

High

1311669

SYT17
Synaptotagmin-17

2

4

High-throughput

0.553

High

1287128

HAUS1
HAUS augmin-like complex subunit 1

1

0

High-throughput

0.549

High

1357290

SPAT2
Spermatogenesis-associated protein 2

1

0

High-throughput

0.549

High

750567

COIL
Coilin

1

1

High-throughput

0.541

High

843986

FXR1
RNA-binding protein FXR1

1

6

High-throughput

0.541

High

1069839

NONO
Non-POU domain-containing octamer-binding protein

1

12

High-throughput

0.541

High

1377275

NINL
Ninein-like protein

1

18

High-throughput

0.541

High

1377288

AMOL2
Angiomotin-like protein 2

1

17

High-throughput

0.541

High

303868

CCNB2
G2/mitotic-specific cyclin-B2

1

1

High-throughput

0.536

High

626304

APC
Adenomatous polyposis coli protein

1

10

High-throughput

0.536

High

871847

HSP72
Heat shock-related 70 kDa protein 2

1

10

High-throughput

0.536

High

905321

1433G
14-3-3 protein gamma

1

20

High-throughput

0.536

High

982669

1433F
14-3-3 protein eta

1

20

High-throughput

0.536

High

1038855

HDAC1
Histone deacetylase 1

1

20

Small-scale

0.536

High

1039980

SNW1
SNW domain-containing protein 1

1

3

High-throughput

0.536

High

1270547

HDAC2
Histone deacetylase 2

1

20

Small-scale

0.536

High

1303903

CDC5L
Cell division cycle 5-like protein

1

3

High-throughput

0.536

High

1306188

NPAS1
Neuronal PAS domain-containing protein 1

1

8

High-throughput

0.536

High

1332217

ASB7
Ankyrin repeat and SOCS box protein 7

1

3

High-throughput

0.536

High

1349620

FOXJ2
Forkhead box protein J2

1

5

High-throughput

0.536

High

1023846

TRAF1
TNF receptor-associated factor 1

1

3

High-throughput

0.515

High

1101803

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.513

High

1260626

BRK1
Protein BRICK1

1

0

High-throughput

0.513

High

1313298

DHRS6
Dehydrogenase/reductase SDR family member 6

1

0

High-throughput

0.513

High

476655

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

11

High-throughput

0.501

High

1036382

BIRC2
Baculoviral IAP repeat-containing protein 2

1

5

Small-scale

0.501

High

1302486

SIN3A
Paired amphipathic helix protein Sin3a

1

1

Small-scale

0.501

High

1297699

PACRG
Parkin coregulated gene protein

1

0

High-throughput

0.493

High

1132277

CF141
Uncharacterized protein C6orf141

1

1

High-throughput

0.489

High

1224927

FAM9B
Protein FAM9B

1

1

High-throughput

0.489

High

1264145

PIBF1
Progesterone-induced-blocking factor 1

1

2

High-throughput

0.481

High

1355118

GCP4
Gamma-tubulin complex component 4

1

1

High-throughput

0.481

High

216118

NRDC
Nardilysin

1

2

Small-scale

0.479

High

570240

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.479

High

610803

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

14

Small-scale

0.479

High

672936

CDC27
Cell division cycle protein 27 homolog

1

1

Small-scale

0.479

High

780413

CCNF
Cyclin-F

1

5

High-throughput

0.479

High

1027354

CBX3
Chromobox protein homolog 3

1

5

High-throughput

0.479

High

1076026

PCH2
Pachytene checkpoint protein 2 homolog

1

7

Small-scale

0.479

High

1139793

MT21C
Protein-lysine methyltransferase METTL21C

1

6

High-throughput

0.479

High

1172482

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.479

High

1246212

COP1
E3 ubiquitin-protein ligase COP1

1

19

High-throughput

0.479

High

1270051

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1281893

FBX32
F-box only protein 32

1

9

High-throughput

0.479

High

1307538

VRK1
Serine/threonine-protein kinase VRK1

1

4

High-throughput

0.479

High

1331224

SENP3
Sentrin-specific protease 3

1

1

Small-scale

0.479

High

1355044

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1356585

IKZF3
Zinc finger protein Aiolos

1

3

High-throughput

0.479

High

1116754

Q4G0R1
PIBF1 protein

1

2

High-throughput

0.470

High

1138404

Q5VU62
TPM3 protein

1

16

High-throughput

0.470

High

1356290

VPS28
Vacuolar protein sorting-associated protein 28 homolog

1

0

High-throughput

0.458

High

129075

PLK4
Serine/threonine-protein kinase PLK4

1

16

High-throughput

0.457

High

443904

VIME
Vimentin

1

20

High-throughput

0.457

High

537152

TRI27
Zinc finger protein RFP

1

6

High-throughput

0.457

High

1313822

KIFC3
Kinesin-like protein KIFC3

1

2

Small-scale

0.457

High

1314158

Q9BVR6
Gamma-tubulin complex component

1

1

High-throughput

0.457

High

497902

TAU
Microtubule-associated protein tau

1

10

High-throughput

0.445

High

385814

NTRK1
High affinity nerve growth factor receptor

1

15

High-throughput

0.437

High

1304738

MNT
Max-binding protein MNT

1

14

Small-scale

0.437

High

316227

PRA12
PRAME family member 12

1

0

High-throughput

0.426

High

1103287

C19L2
CWF19-like protein 2

3

0

High-throughput

0.352

High

1223151

TEX11
Testis-expressed protein 11

2

0

High-throughput

0.317

High

198786

CMIP4
Ciliary microtubule inner protein 4

2

0

High-throughput

0.316

High

1205656

F90A1
Protein FAM90A1

2

0

High-throughput

0.316

High

1286132

LENG1
Leukocyte receptor cluster member 1

2

0

High-throughput

0.316

High

1377838

TCAF1
TRPM8 channel-associated factor 1

2

0

High-throughput

0.316

High

1314516

YJU2
Splicing factor YJU2

1

0

High-throughput

0.299

High

1284560

F131C
Protein FAM131C

1

0

High-throughput

0.282

High

1292624

RUSF1
RUS family member 1

1

0

High-throughput

0.279

Low

1149880

SCAR3
Scavenger receptor class A member 3

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024