Protein: RHG18
Rho GTPase-activating protein 18 (MacGAP) (Rho-type GTPase-activating protein 18)

Gene: RHG18, ARHGAP18
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q8N392

Gene Ontology (top 5):
GO:0001726 - ruffle
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005881 - cytoplasmic microtubule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

914206

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.618

High

915827

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

1035501

SMAD4
Mothers against decapentaplegic homolog 4

2

3

High-throughput

0.611

High

1174466

PREX2
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein

2

8

High-throughput

0.571

High

1191871

FGD2
FYVE, RhoGEF and PH domain-containing protein 2

2

8

High-throughput

0.571

High

1232126

PKH4B
Pleckstrin homology domain-containing family G member 4B

2

5

High-throughput

0.571

High

238420

JAK2
Tyrosine-protein kinase JAK2

1

20

High-throughput

0.536

High

258101

DNJB6
DnaJ homolog subfamily B member 6

1

1

High-throughput

0.536

High

934303

CSK21
Casein kinase II subunit alpha

1

12

High-throughput

0.536

High

1232112

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.536

High

1232117

DOK4
Docking protein 4

1

4

High-throughput

0.536

High

1232120

PGTA
Geranylgeranyl transferase type-2 subunit alpha

1

4

High-throughput

0.536

High

1232116

BBS1
Bardet-Biedl syndrome 1 protein

1

0

High-throughput

0.513

High

1232123

APC16
Anaphase-promoting complex subunit 16

1

0

High-throughput

0.513

High

1232131

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.513

High

1232149

RM42
Large ribosomal subunit protein mL42

1

0

High-throughput

0.513

High

301147

KDM4B
Lysine-specific demethylase 4B

1

3

High-throughput

0.489

High

1229737

ZN444
Zinc finger protein 444

1

12

High-throughput

0.489

High

1232113

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

17

High-throughput

0.489

High

1232119

ANR49
Ankyrin repeat domain-containing protein 49

1

10

High-throughput

0.489

High

1232139

PALS2
Protein PALS2

1

4

High-throughput

0.481

High

124435

HIP1
Huntingtin-interacting protein 1

1

3

High-throughput

0.479

High

128883

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

1

High-throughput

0.479

High

130985

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

1

High-throughput

0.479

High

161685

GAK
Cyclin-G-associated kinase

1

7

High-throughput

0.479

High

164964

SC16A
Protein transport protein Sec16A

1

4

High-throughput

0.479

High

167705

LSM1
U6 snRNA-associated Sm-like protein LSm1

1

1

High-throughput

0.479

High

212646

AP1G1
AP-1 complex subunit gamma-1

1

8

High-throughput

0.479

High

214988

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

2

High-throughput

0.479

High

228036

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

302183

AP2A2
AP-2 complex subunit alpha-2

1

8

High-throughput

0.479

High

307545

EPN2
Epsin-2

1

3

High-throughput

0.479

High

323886

BAG2
BAG family molecular chaperone regulator 2

1

4

High-throughput

0.479

High

364347

TFR1
Transferrin receptor protein 1

1

1

High-throughput

0.479

High

451497

CLCA
Clathrin light chain A

1

2

High-throughput

0.479

High

451705

CLCB
Clathrin light chain B

1

2

High-throughput

0.479

High

504390

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

522057

CADH1
Cadherin-1

1

8

High-throughput

0.479

High

602269

CD9
CD9 antigen

1

1

High-throughput

0.479

High

640540

DDX6
Probable ATP-dependent RNA helicase DDX6

1

5

High-throughput

0.479

High

646222

STOM
Stomatin

1

4

High-throughput

0.479

High

751722

GRP75
Stress-70 protein, mitochondrial

1

7

High-throughput

0.479

High

787945

EPS15
Epidermal growth factor receptor substrate 15

1

3

High-throughput

0.479

High

864089

AP2S1
AP-2 complex subunit sigma

1

3

High-throughput

0.479

High

871666

HSP72
Heat shock-related 70 kDa protein 2

1

3

High-throughput

0.479

High

878203

SEC13
Protein SEC13 homolog

1

4

High-throughput

0.479

High

912237

LSM6
U6 snRNA-associated Sm-like protein LSm6

1

5

High-throughput

0.479

High

925944

AP2B1
AP-2 complex subunit beta

1

10

High-throughput

0.479

High

995040

GOGA2
Golgin subfamily A member 2

1

6

High-throughput

0.479

High

1014048

AP1B1
AP-1 complex subunit beta-1

1

9

High-throughput

0.479

High

1024374

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

5

High-throughput

0.479

High

1036434

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

4

High-throughput

0.479

High

1057069

EPN4
Clathrin interactor 1

1

3

High-throughput

0.479

High

1158977

EDC4
Enhancer of mRNA-decapping protein 4

1

2

High-throughput

0.479

High

1170790

TRI67
Tripartite motif-containing protein 67

1

18

High-throughput

0.479

High

1224168

DCP1B
mRNA-decapping enzyme 1B

1

5

High-throughput

0.479

High

1224364

XRN1
5'-3' exoribonuclease 1

1

1

High-throughput

0.479

High

1232114

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

5

High-throughput

0.479

High

1232115

LS14A
Protein LSM14 homolog A

1

2

High-throughput

0.479

High

1232118

SMAP2
Stromal membrane-associated protein 2

1

4

High-throughput

0.479

High

1232121

AP2M1
AP-2 complex subunit mu

1

2

High-throughput

0.479

High

1232122

REPS1
RalBP1-associated Eps domain-containing protein 1

1

5

High-throughput

0.479

High

1232125

EDC3
Enhancer of mRNA-decapping protein 3

1

1

High-throughput

0.479

High

1232130

AP1M1
AP-1 complex subunit mu-1

1

2

High-throughput

0.479

High

1232133

WDR6
tRNA

1

8

High-throughput

0.479

High

1232134

DCP1A
mRNA-decapping enzyme 1A

1

1

High-throughput

0.479

High

1232136

BMP2K
BMP-2-inducible protein kinase

1

6

High-throughput

0.479

High

1232140

CHMP5
Charged multivesicular body protein 5

1

2

High-throughput

0.479

High

1232141

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

1

5

High-throughput

0.479

High

1232142

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1232145

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

3

High-throughput

0.479

High

1232147

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

3

High-throughput

0.479

High

1232148

CD2AP
CD2-associated protein

1

19

High-throughput

0.479

High

262035

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.458

High

314095

BAG4
BAG family molecular chaperone regulator 4

1

0

High-throughput

0.458

High

867052

IST1
IST1 homolog

1

0

High-throughput

0.458

High

960882

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.458

High

1056080

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

1084274

MEA1
Male-enhanced antigen 1

1

0

High-throughput

0.458

High

1129694

NEXMI
Neurite extension and migration factor

1

0

High-throughput

0.458

High

1144527

AP1AR
AP-1 complex-associated regulatory protein

1

0

High-throughput

0.458

High

1164818

AFTIN
Aftiphilin

1

0

High-throughput

0.458

High

1198357

PATL1
Protein PAT1 homolog 1

1

0

High-throughput

0.458

High

1215860

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.458

High

1232135

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.458

High

1232138

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.458

High

1232143

SYNRG
Synergin gamma

1

0

High-throughput

0.458

High

1232144

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

0

High-throughput

0.458

High

1232146

MARF1
Meiosis regulator and mRNA stability factor 1

1

0

High-throughput

0.458

High

1232150

ENPP4
Bis(5'-adenosyl)-triphosphatase ENPP4

1

0

High-throughput

0.458

High

1023081

STK4
Serine/threonine-protein kinase 4

1

11

High-throughput

0.445

High

1232128

MPH6
M-phase phosphoprotein 6

1

0

High-throughput

0.438

High

329834

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

873453

P5CS
Delta-1-pyrroline-5-carboxylate synthase

1

3

High-throughput

0.437

High

1150532

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

3

High-throughput

0.437

High

1159502

SCYL2
SCY1-like protein 2

1

1

High-throughput

0.437

High

1232124

ZBT10
Zinc finger and BTB domain-containing protein 10

1

15

High-throughput

0.437

High

1232127

MA7D2
MAP7 domain-containing protein 2

1

12

High-throughput

0.437

High

1232132

YTDC2
3'-5' RNA helicase YTHDC2

1

2

High-throughput

0.437

High

1232129

MND1
Meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.279

Low

1232137

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.279

Low

1016557

PNRC1
Proline-rich nuclear receptor coactivator 1

1

0

High-throughput

0.249

Low

1131303

TSBP1
Testis-expressed basic protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024