Protein: TIGAR
Fructose-2,6-bisphosphatase TIGAR (EC 3.1.3.46) (TP53-induced glycolysis and apoptosis regulator) (TP53-induced glycolysis regulatory phosphatase)

Gene: TIGAR
Organism: Homo sapiens
Interactions: 42
UniProt ID: Q9NQ88

Gene Ontology (top 5):
GO:0000423 - mitophagy
GO:0002931 - response to ischemia
GO:0004331 - fructose-2,6-bisphosphate 2-phosphatase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1016521

TWF1
Twinfilin-1

2

1

High-throughput

0.621

High

782861

PLPL4
Patatin-like phospholipase domain-containing protein 4

2

0

High-throughput

0.602

High

1081252

NF2L2
Nuclear factor erythroid 2-related factor 2

1

2

Small-scale

0.561

High

686752

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.536

High

885833

MTPN
Myotrophin

1

1

High-throughput

0.536

High

1343232

KLK13
Kallikrein-13

1

1

High-throughput

0.536

High

856243

HXK2
Hexokinase-2

1

4

Small-scale

0.534

High

923237

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.518

High

124470

HIP1
Huntingtin-interacting protein 1

1

2

High-throughput

0.515

High

1343235

SHLB1
Endophilin-B1

1

1

High-throughput

0.515

High

1030693

NMI
N-myc-interactor

1

0

High-throughput

0.513

High

1219031

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1331823

GSX1
GS homeobox 1

1

0

High-throughput

0.513

High

1343231

PHF11
PHD finger protein 11

1

0

High-throughput

0.513

High

1343236

NGN3
Neurogenin-3

1

0

High-throughput

0.513

High

395851

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

877149

CASP6
Caspase-6

1

0

High-throughput

0.493

High

125732

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

5

High-throughput

0.479

High

228790

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

272726

OFD1
Centriole and centriolar satellite protein OFD1

1

1

High-throughput

0.479

High

502585

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.479

High

553798

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

652332

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

882591

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.479

High

1171843

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

1290072

RNF31
E3 ubiquitin-protein ligase RNF31

1

5

Small-scale

0.479

High

1318507

TRI31
E3 ubiquitin-protein ligase TRIM31

1

3

Small-scale

0.479

High

1343230

DNJB4
DnaJ homolog subfamily B member 4

1

4

High-throughput

0.479

High

1343233

TRI35
E3 ubiquitin-protein ligase TRIM35

1

2

Small-scale

0.479

High

1188903

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1244713

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1327701

SHRPN
Sharpin

1

0

Small-scale

0.458

High

1343229

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

1130624

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

721526

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

1239447

F184A
Protein FAM184A

1

1

High-throughput

0.437

High

1281743

PIGT
GPI transamidase component PIG-T

1

0

High-throughput

0.279

Low

1307293

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.279

Low

1313952

ALG8
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase

1

0

High-throughput

0.279

Low

1343234

NTNG1
Netrin-G1

1

0

High-throughput

0.279

Low

527820

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.268

Low

353822

IGHG2
Immunoglobulin heavy constant gamma 2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024