Protein: GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

Gene: GPC1
Organism: Homo sapiens
Interactions: 182
UniProt ID: P35052

Gene Ontology (top 5):
GO:0005507 - copper ion binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005654 - nucleoplasm
GO:0005768 - endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

714869

ERMAP
Erythroid membrane-associated protein

1

1

High-throughput

0.691

High

714868

CAMKV
CaM kinase-like vesicle-associated protein

3

3

High-throughput

0.675

High

399138

FGF1
Fibroblast growth factor 1

3

8

High-throughput

0.667

High

686794

GP183
G-protein coupled receptor 183

3

3

High-throughput

0.667

High

714835

CEAM7
Carcinoembryonic antigen-related cell adhesion molecule 7

1

1

High-throughput

0.665

High

182102

PDPK1
3-phosphoinositide-dependent protein kinase 1

3

3

High-throughput

0.650

High

714876

XYLT2
Xylosyltransferase 2

2

1

High-throughput

0.628

High

714870

HBEGF
Proheparin-binding EGF-like growth factor [Cleaved into: Heparin-binding EGF-like growth factor

2

1

High-throughput

0.611

High

619203

AT2B4
Plasma membrane calcium-transporting ATPase 4

2

0

High-throughput

0.602

High

714798

ECHB
Trifunctional enzyme subunit beta, mitochondrial

2

0

High-throughput

0.602

High

714856

TM214
Transmembrane protein 214

2

0

High-throughput

0.602

High

714878

FANCE
Fanconi anemia group E protein

2

0

High-throughput

0.602

High

714889

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

0

High-throughput

0.602

High

475402

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

1

High-throughput

0.595

High

714802

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

2

1

Small-scale

0.595

High

714843

SPCS2
Signal peptidase complex subunit 2

2

2

High-throughput

0.574

High

714837

DAG1
Dystroglycan 1

2

1

Small-scale

0.571

High

296643

SLIT2
Slit homolog 2 protein

1

1

Small-scale

0.561

High

359702

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

0

High-throughput

0.559

High

441815

FGF4
Fibroblast growth factor 4

1

8

High-throughput

0.536

High

451993

WNT2
Protein Wnt-2

1

5

High-throughput

0.536

High

532903

PRG2
Bone marrow proteoglycan

1

2

High-throughput

0.536

High

714784

SRP14
Signal recognition particle 14 kDa protein

1

1

High-throughput

0.536

High

714793

SRP09
Signal recognition particle 9 kDa protein

1

2

High-throughput

0.536

High

714795

TUB
Tubby protein homolog

1

4

High-throughput

0.536

High

714852

ODAPH
Odontogenesis associated phosphoprotein

1

1

High-throughput

0.536

High

714864

LRRT4
Leucine-rich repeat transmembrane neuronal protein 4

1

9

High-throughput

0.536

High

714865

LRRT3
Leucine-rich repeat transmembrane neuronal protein 3

1

9

High-throughput

0.536

High

714874

RTN4R
Reticulon-4 receptor

1

10

High-throughput

0.536

High

714883

DAXX
Death domain-associated protein 6

1

1

High-throughput

0.536

High

714884

ALK
ALK tyrosine kinase receptor

1

1

High-throughput

0.536

High

714857

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.513

High

714871

CGRF1
Cell growth regulator with RING finger domain protein 1

1

0

High-throughput

0.513

High

714887

FLVC1
Heme transporter FLVCR1

1

0

High-throughput

0.513

High

394213

A4
Amyloid-beta precursor protein

1

3

Small-scale

0.501

High

549558

VEGFA
Vascular endothelial growth factor A, long form

1

1

Small-scale

0.501

High

714788

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

4

High-throughput

0.489

High

714888

SPCS1
Signal peptidase complex subunit 1

1

1

High-throughput

0.489

High

253779

XYLK
Glycosaminoglycan xylosylkinase

1

0

Small-scale

0.480

High

124582

CLIC1
Chloride intracellular channel protein 1

1

1

High-throughput

0.479

High

152261

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

1

High-throughput

0.479

High

202071

HNRPR
Heterogeneous nuclear ribonucleoprotein R

1

1

High-throughput

0.479

High

235730

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

1

High-throughput

0.479

High

238148

PLIN3
Perilipin-3

1

1

High-throughput

0.479

High

261209

FLNB
Filamin-B

1

2

High-throughput

0.479

High

341490

UROK
Urokinase-type plasminogen activator

1

7

High-throughput

0.479

High

376368

PDGFA
Platelet-derived growth factor subunit A

1

1

High-throughput

0.479

High

403802

ITB1
Integrin beta-1

1

1

High-throughput

0.479

High

416581

S10A6
Protein S100-A6

1

3

High-throughput

0.479

High

417980

NPM
Nucleophosmin

1

1

High-throughput

0.479

High

489913

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

8

High-throughput

0.479

High

521756

CADH1
Cadherin-1

1

1

High-throughput

0.479

High

547457

FOLR1
Folate receptor alpha

1

1

High-throughput

0.479

High

556419

ITB4
Integrin beta-4

1

10

High-throughput

0.479

High

597979

FLNA
Filamin-A

1

2

High-throughput

0.479

High

606299

CADH3
Cadherin-3

1

1

High-throughput

0.479

High

614257

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

1

High-throughput

0.479

High

623073

EF1B
Elongation factor 1-beta

1

1

High-throughput

0.479

High

643944

EF1G
Elongation factor 1-gamma

1

1

High-throughput

0.479

High

646670

1433T
14-3-3 protein theta

1

3

High-throughput

0.479

High

654113

CALX
Calnexin

1

3

High-throughput

0.479

High

669282

EF1D
Elongation factor 1-delta

1

1

High-throughput

0.479

High

683869

1433S
14-3-3 protein sigma

1

3

High-throughput

0.479

High

685157

S10AB
Protein S100-A11

1

3

High-throughput

0.479

High

714785

GRP75
Stress-70 protein, mitochondrial

1

2

High-throughput

0.479

High

714786

TCPZ
T-complex protein 1 subunit zeta

1

1

High-throughput

0.479

High

714791

RS5
Small ribosomal subunit protein uS7

1

1

High-throughput

0.479

High

714811

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.479

High

714812

FKB1A
Peptidyl-prolyl cis-trans isomerase FKBP1A

1

1

High-throughput

0.479

High

714816

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

714822

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

2

High-throughput

0.479

High

714824

REL
Proto-oncogene c-Rel

1

4

High-throughput

0.479

High

714825

1433F
14-3-3 protein eta

1

3

High-throughput

0.479

High

714828

ILF3
Interleukin enhancer-binding factor 3

1

1

High-throughput

0.479

High

714829

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

1

High-throughput

0.479

High

714830

ROA0
Heterogeneous nuclear ribonucleoprotein A0

1

1

High-throughput

0.479

High

714832

SQSTM
Sequestosome-1

1

1

High-throughput

0.479

High

714833

LAMB3
Laminin subunit beta-3

1

1

High-throughput

0.479

High

714834

LAMC2
Laminin subunit gamma-2

1

3

High-throughput

0.479

High

714838

DSG2
Desmoglein-2

1

2

High-throughput

0.479

High

714840

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

4

High-throughput

0.479

High

714844

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

714845

PLEC
Plectin

1

1

High-throughput

0.479

High

714850

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

714851

LAMA3
Laminin subunit alpha-3

1

3

High-throughput

0.479

High

714855

IFIX
Pyrin and HIN domain-containing protein 1

1

3

High-throughput

0.479

High

714866

TAXB1
Tax1-binding protein 1

1

1

High-throughput

0.479

High

714879

S10AE
Protein S100-A14

1

3

High-throughput

0.479

High

714880

ANLN
Anillin

1

1

High-throughput

0.479

High

714882

HDAC6
Histone deacetylase 6

1

1

High-throughput

0.479

High

153883

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

0

High-throughput

0.458

High

205102

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

233243

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

282408

STC2
Stanniocalcin-2

1

0

High-throughput

0.458

High

340393

PGK1
Phosphoglycerate kinase 1

1

0

High-throughput

0.458

High

346073

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

376179

ANXA1
Annexin A1

1

0

High-throughput

0.458

High

382325

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

0

High-throughput

0.458

High

418891

TPM3
Tropomyosin alpha-3 chain

1

0

High-throughput

0.458

High

429301

SAP
Prosaposin

1

0

High-throughput

0.458

High

445296

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.458

High

454684

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.458

High

500735

CLUS
Clusterin

1

0

High-throughput

0.458

High

526878

TDGF1
Protein Cripto

1

0

Small-scale

0.458

High

548060

UCHL3
Ubiquitin carboxyl-terminal hydrolase isozyme L3

1

0

High-throughput

0.458

High

550623

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

555086

CD44
CD44 antigen

1

0

High-throughput

0.458

High

562888

STMN1
Stathmin

1

0

High-throughput

0.458

High

564815

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.458

High

582090

NUCL
Nucleolin

1

0

High-throughput

0.458

High

617809

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.458

High

618539

IF4B
Eukaryotic translation initiation factor 4B

1

0

High-throughput

0.458

High

639871

ITA3
Integrin alpha-3

1

0

High-throughput

0.458

High

642195

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.458

High

643719

SYTC
Threonine--tRNA ligase 1, cytoplasmic

1

0

High-throughput

0.458

High

660410

GRN
Progranulin

1

0

High-throughput

0.458

High

670811

PRDX5
Peroxiredoxin-5, mitochondrial

1

0

High-throughput

0.458

High

671144

RL12
Large ribosomal subunit protein uL11

1

0

High-throughput

0.458

High

671553

KCY
UMP-CMP kinase

1

0

High-throughput

0.458

High

684441

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

714106

HSP74
Heat shock 70 kDa protein 4

1

0

High-throughput

0.458

High

714782

CTNB1
Catenin beta-1

1

0

High-throughput

0.458

High

714783

BASI
Basigin

1

0

High-throughput

0.458

High

714787

MDHC
Malate dehydrogenase, cytoplasmic

1

0

High-throughput

0.458

High

714790

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.458

High

714792

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.458

High

714794

HINT1
Adenosine 5'-monophosphoramidase HINT1

1

0

High-throughput

0.458

High

714796

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.458

High

714797

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.458

High

714800

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.458

High

714801

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

714803

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

714805

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

0

High-throughput

0.458

High

714806

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.458

High

714807

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.458

High

714808

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

714809

RS25
Small ribosomal subunit protein eS25

1

0

High-throughput

0.458

High

714810

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.458

High

714813

RACK1
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

714814

YBOX1
Y-box-binding protein 1

1

0

High-throughput

0.458

High

714818

DHSO
Sorbitol dehydrogenase

1

0

High-throughput

0.458

High

714819

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

High-throughput

0.458

High

714820

SRSF2
Serine/arginine-rich splicing factor 2

1

0

High-throughput

0.458

High

714821

CAP1
Adenylyl cyclase-associated protein 1

1

0

High-throughput

0.458

High

714823

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.458

High

714831

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.458

High

714836

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

0

High-throughput

0.458

High

714839

SRC8
Src substrate cortactin

1

0

High-throughput

0.458

High

714841

CAPR1
Caprin-1

1

0

High-throughput

0.458

High

714842

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.458

High

714846

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.458

High

714847

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.458

High

714848

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.458

High

714849

VAS1
V-type proton ATPase subunit S1

1

0

High-throughput

0.458

High

714862

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

714867

TXND5
Thioredoxin domain-containing protein 5

1

0

High-throughput

0.458

High

714872

MEP50
Methylosome protein WDR77

1

0

High-throughput

0.458

High

714873

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

714875

RGAP1
Rac GTPase-activating protein 1

1

0

High-throughput

0.458

High

714885

NSF1C
NSFL1 cofactor p47

1

0

High-throughput

0.458

High

714886

STRAP
Serine-threonine kinase receptor-associated protein

1

0

High-throughput

0.458

High

714854

PKHA7
Pleckstrin homology domain-containing family A member 7

1

2

High-throughput

0.445

High

714827

FSTL1
Follistatin-related protein 1

1

0

Small-scale

0.438

High

661211

S10A2
Protein S100-A2

1

3

High-throughput

0.437

High

714799

NP1L1
Nucleosome assembly protein 1-like 1

1

1

High-throughput

0.437

High

714858

GP179
Probable G-protein coupled receptor 179

1

1

Small-scale

0.437

High

714860

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

207613

AKA10
A-kinase anchor protein 10, mitochondrial

1

0

High-throughput

0.426

High

714789

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

High-throughput

0.426

High

714826

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.426

High

714815

SC11A
Signal peptidase complex catalytic subunit SEC11A

2

0

High-throughput

0.328

High

714877

TM245
Transmembrane protein 245

2

0

High-throughput

0.328

High

714804

SPCS3
Signal peptidase complex subunit 3

1

0

High-throughput

0.279

Low

714861

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

0

High-throughput

0.279

Low

714881

RMND1
Required for meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.279

Low

202728

TPD54
Tumor protein D54

1

0

High-throughput

0.249

Low

536319

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.249

Low

559338

H13
Histone H1.3

1

0

High-throughput

0.249

Low

714817

ERH
Enhancer of rudimentary homolog

1

0

High-throughput

0.249

Low

714863

OAF
Out at first protein homolog

1

0

High-throughput

0.249

Low

714859

DUX4C
Double homeobox protein 4C

1

0

High-throughput

0.238

Low

714853

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024