Protein: HNF1B
Hepatocyte nuclear factor 1-beta (HNF-1-beta) (HNF-1B) (Homeoprotein LFB3) (Transcription factor 2) (TCF-2) (Variant hepatic nuclear factor 1) (vHNF1)

Gene: HNF1B
Organism: Homo sapiens
Interactions: 189
UniProt ID: P35680

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001221 - transcription coregulator binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

727496

PHS
Pterin-4-alpha-carbinolamine dehydratase

6

6

High-throughput

0.737

High

595909

HNF1A
Hepatocyte nuclear factor 1-alpha

5

16

Small-scale

0.713

High

727585

PHS2
Pterin-4-alpha-carbinolamine dehydratase 2

2

6

High-throughput

0.611

High

197667

CRX
Cone-rod homeobox protein

2

20

High-throughput

0.606

High

686546

OTX2
Homeobox protein OTX2

2

20

High-throughput

0.606

High

727493

AF10
Protein AF-10

2

5

High-throughput

0.606

High

727499

PO6F2
POU domain, class 6, transcription factor 2

2

20

High-throughput

0.606

High

727511

VAC14
Protein VAC14 homolog

2

1

High-throughput

0.606

High

727478

HNF1B
Hepatocyte nuclear factor 1-beta

2

16

Small-scale

0.595

High

632622

TYY1
Transcriptional repressor protein YY1

1

9

High-throughput

0.561

High

727532

CJ055
Uncharacterized protein C10orf55

2

1

High-throughput

0.553

High

727541

UFSP1
Inactive Ufm1-specific protease 1

2

2

High-throughput

0.553

High

727543

KR261
Keratin-associated protein 26-1

2

1

High-throughput

0.553

High

727594

BPIA1
BPI fold-containing family A member 1

2

1

High-throughput

0.553

High

727506

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

4

High-throughput

0.536

High

211801

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.501

High

213301

TLX2
T-cell leukemia homeobox protein 2

1

19

High-throughput

0.501

High

225710

SOX15
Transcription factor SOX-15

1

20

High-throughput

0.501

High

271739

PRDM1
PR domain zinc finger protein 1

1

4

High-throughput

0.501

High

620129

PAX7
Paired box protein Pax-7

1

18

High-throughput

0.501

High

641330

PAX6
Paired box protein Pax-6

1

18

High-throughput

0.501

High

727479

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.501

High

727480

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.501

High

727487

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.501

High

727488

SOX9
Transcription factor SOX-9

1

20

High-throughput

0.501

High

727495

SOX10
Transcription factor SOX-10

1

20

High-throughput

0.501

High

727498

H31
Histone H3.1

1

5

Small-scale

0.501

High

727503

PAX2
Paired box protein Pax-2

1

16

High-throughput

0.501

High

727508

PAX8
Paired box protein Pax-8

1

16

High-throughput

0.501

High

727525

TBR1
T-box brain protein 1

1

12

High-throughput

0.501

High

727533

OTUD3
OTU domain-containing protein 3

1

1

Small-scale

0.501

High

727564

SP7
Transcription factor Sp7

1

4

High-throughput

0.501

High

727575

LHX4
LIM/homeobox protein Lhx4

1

12

High-throughput

0.501

High

727590

SOX17
Transcription factor SOX-17

1

20

High-throughput

0.501

High

556797

CREB1
Cyclic AMP-responsive element-binding protein 1

1

1

Small-scale

0.481

High

579127

ATF1
Cyclic AMP-dependent transcription factor ATF-1

1

3

Small-scale

0.481

High

124585

CLIC1
Chloride intracellular channel protein 1

1

1

High-throughput

0.479

High

131698

BCL9
B-cell CLL/lymphoma 9 protein

1

20

High-throughput

0.479

High

135086

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

146167

ARI1A
AT-rich interactive domain-containing protein 1A

1

20

High-throughput

0.479

High

152601

KMT2D
Histone-lysine N-methyltransferase 2D

1

20

High-throughput

0.479

High

164192

ZN609
Zinc finger protein 609

1

20

High-throughput

0.479

High

167141

ZN536
Zinc finger protein 536

1

7

High-throughput

0.479

High

170278

TIF1A
Transcription intermediary factor 1-alpha

1

15

High-throughput

0.479

High

183071

KDM6A
Lysine-specific demethylase 6A

1

10

High-throughput

0.479

High

231211

ZEB2
Zinc finger E-box-binding homeobox 2

1

13

High-throughput

0.479

High

245568

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

5

High-throughput

0.479

High

260361

ZN217
Zinc finger protein 217

1

4

High-throughput

0.479

High

261420

NCOR1
Nuclear receptor corepressor 1

1

20

High-throughput

0.479

High

277959

PIAS1
E3 SUMO-protein ligase PIAS1

1

2

High-throughput

0.479

High

301653

TRI37
E3 ubiquitin-protein ligase TRIM37

1

5

High-throughput

0.479

High

318582

EYA4
Eyes absent homolog 4

1

20

High-throughput

0.479

High

321716

WIZ
Protein Wiz

1

8

High-throughput

0.479

High

351284

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

3

High-throughput

0.479

High

455155

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.479

High

473478

ATX1L
Ataxin-1-like

1

12

High-throughput

0.479

High

501761

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.479

High

520108

BMP4
Bone morphogenetic protein 4

1

3

High-throughput

0.479

High

523557

XRCC6
X-ray repair cross-complementing protein 6

1

7

High-throughput

0.479

High

525287

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

20

High-throughput

0.479

High

550331

ZEP1
Zinc finger protein 40

1

12

High-throughput

0.479

High

552088

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

716822

CTNB1
Catenin beta-1

1

3

High-throughput

0.479

High

727481

ZEB1
Zinc finger E-box-binding homeobox 1

1

7

High-throughput

0.479

High

727482

IF4A3
Eukaryotic initiation factor 4A-III

1

4

High-throughput

0.479

High

727483

CUX1
Homeobox protein cut-like 1

1

19

High-throughput

0.479

High

727484

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

1

High-throughput

0.479

High

727486

YAP1
Transcriptional coactivator YAP1

1

4

High-throughput

0.479

High

727489

KC1A
Casein kinase I isoform alpha

1

5

High-throughput

0.479

High

727490

SMCA2
Probable global transcription activator SNF2L2

1

20

High-throughput

0.479

High

727491

HIRA
Protein HIRA

1

8

High-throughput

0.479

High

727492

ATX1
Ataxin-1

1

12

High-throughput

0.479

High

727494

AF17
Protein AF-17

1

4

High-throughput

0.479

High

727497

SUMO2
Small ubiquitin-related modifier 2

1

3

High-throughput

0.479

High

727500

FOXK2
Forkhead box protein K2

1

18

High-throughput

0.479

High

727501

SATB1
DNA-binding protein SATB1

1

9

High-throughput

0.479

High

727502

EWS
RNA-binding protein EWS

1

8

High-throughput

0.479

High

727504

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

727505

TLE3
Transducin-like enhancer protein 3

1

20

High-throughput

0.479

High

727507

RING1
E3 ubiquitin-protein ligase RING1

1

15

High-throughput

0.479

High

727510

TLE5
TLE family member 5

1

20

High-throughput

0.479

High

727512

EP300
Histone acetyltransferase p300

1

20

High-throughput

0.479

High

727513

BPTF
Nucleosome-remodeling factor subunit BPTF

1

20

High-throughput

0.479

High

727514

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

727515

FOXC1
Forkhead box protein C1

1

18

High-throughput

0.479

High

727516

GPS2
G protein pathway suppressor 2

1

4

High-throughput

0.479

High

727517

TCOF
Treacle protein

1

20

High-throughput

0.479

High

727519

MEF2D
Myocyte-specific enhancer factor 2D

1

4

High-throughput

0.479

High

727520

ARI5B
AT-rich interactive domain-containing protein 5B

1

20

High-throughput

0.479

High

727521

RBBP5
Retinoblastoma-binding protein 5

1

7

High-throughput

0.479

High

727522

PCBP1
Poly(rC)-binding protein 1

1

3

High-throughput

0.479

High

727523

NCOA2
Nuclear receptor coactivator 2

1

19

High-throughput

0.479

High

727524

ZFHX3
Zinc finger homeobox protein 3

1

13

High-throughput

0.479

High

727527

ZN260
Zinc finger protein 260

1

2

High-throughput

0.479

High

727528

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.479

High

727529

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

10

High-throughput

0.479

High

727531

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

6

High-throughput

0.479

High

727534

LIN9
Protein lin-9 homolog

1

2

High-throughput

0.479

High

727535

ZMYM4
Zinc finger MYM-type protein 4

1

8

High-throughput

0.479

High

727536

ARID2
AT-rich interactive domain-containing protein 2

1

20

High-throughput

0.479

High

727537

NIPBL
Nipped-B-like protein

1

18

High-throughput

0.479

High

727538

LIN54
Protein lin-54 homolog

1

1

High-throughput

0.479

High

727539

TET2
Methylcytosine dioxygenase TET2

1

1

High-throughput

0.479

High

727540

HMBX1
Homeobox-containing protein 1

1

15

High-throughput

0.479

High

727542

NFRKB
Nuclear factor related to kappa-B-binding protein

1

11

High-throughput

0.479

High

727544

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

10

High-throughput

0.479

High

727545

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

12

High-throughput

0.479

High

727546

MCAF1
Activating transcription factor 7-interacting protein 1

1

20

High-throughput

0.479

High

727547

BCOR
BCL-6 corepressor

1

9

High-throughput

0.479

High

727548

UBN2
Ubinuclein-2

1

17

High-throughput

0.479

High

727549

PAXI1
PAX-interacting protein 1

1

20

High-throughput

0.479

High

727551

ASXL2
Putative Polycomb group protein ASXL2

1

10

High-throughput

0.479

High

727552

POGZ
Pogo transposable element with ZNF domain

1

5

High-throughput

0.479

High

727553

LDB1
LIM domain-binding protein 1

1

7

High-throughput

0.479

High

727554

PB1
Protein polybromo-1

1

16

High-throughput

0.479

High

727555

ZFHX4
Zinc finger homeobox protein 4

1

12

High-throughput

0.479

High

727557

ARI3B
AT-rich interactive domain-containing protein 3B

1

20

High-throughput

0.479

High

727558

MGAP
MAX gene-associated protein

1

11

High-throughput

0.479

High

727559

RYBP
RING1 and YY1-binding protein

1

4

High-throughput

0.479

High

727560

KMT2C
Histone-lysine N-methyltransferase 2C

1

20

High-throughput

0.479

High

727561

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

727562

NUP35
Nucleoporin NUP35

1

1

High-throughput

0.479

High

727563

KDM2B
Lysine-specific demethylase 2B

1

9

High-throughput

0.479

High

727566

MORC4
MORC family CW-type zinc finger protein 4

1

5

High-throughput

0.479

High

727567

GATD1
GATA zinc finger domain-containing protein 1

1

1

High-throughput

0.479

High

727568

BCL7C
B-cell CLL/lymphoma 7 protein family member C

1

10

High-throughput

0.479

High

727569

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

727570

MAML1
Mastermind-like protein 1

1

20

High-throughput

0.479

High

727571

DPF1
Zinc finger protein neuro-d4

1

20

High-throughput

0.479

High

727572

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

727573

CBP
CREB-binding protein

1

20

High-throughput

0.479

High

727574

SMRC1
SWI/SNF complex subunit SMARCC1

1

20

High-throughput

0.479

High

727576

MBD6
Methyl-CpG-binding domain protein 6

1

20

High-throughput

0.479

High

727577

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

12

High-throughput

0.479

High

727578

EP400
E1A-binding protein p400

1

17

High-throughput

0.479

High

727579

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

727580

ARI3A
AT-rich interactive domain-containing protein 3A

1

20

High-throughput

0.479

High

727581

PCGF1
Polycomb group RING finger protein 1

1

13

High-throughput

0.479

High

727582

PAGR1
PAXIP1-associated glutamate-rich protein 1

1

1

High-throughput

0.479

High

727583

UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats

1

2

High-throughput

0.479

High

727584

SP130
Histone deacetylase complex subunit SAP130

1

20

High-throughput

0.479

High

727586

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

1

5

High-throughput

0.479

High

727587

ING2
Inhibitor of growth protein 2

1

9

High-throughput

0.479

High

727589

FOXP1
Forkhead box protein P1

1

20

High-throughput

0.479

High

727591

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

6

High-throughput

0.479

High

727592

BRMS1
Breast cancer metastasis-suppressor 1

1

6

High-throughput

0.479

High

727593

SHCAF
SIN3-HDAC complex-associated factor

1

2

High-throughput

0.479

High

727595

HM20A
High mobility group protein 20A

1

20

High-throughput

0.479

High

727596

UBN1
Ubinuclein-1

1

11

High-throughput

0.479

High

727597

BRD7
Bromodomain-containing protein 7

1

20

High-throughput

0.479

High

727598

TF7L2
Transcription factor 7-like 2

1

20

High-throughput

0.479

High

727599

ING3
Inhibitor of growth protein 3

1

5

High-throughput

0.479

High

727600

BCLF1
Bcl-2-associated transcription factor 1

1

4

High-throughput

0.479

High

727601

BICRA
BRD4-interacting chromatin-remodeling complex-associated protein

1

20

High-throughput

0.479

High

727602

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

1

20

High-throughput

0.479

High

727603

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

14

High-throughput

0.479

High

727604

TRPS1
Zinc finger transcription factor Trps1

1

11

High-throughput

0.479

High

727605

DACH1
Dachshund homolog 1

1

3

High-throughput

0.479

High

727606

SIX4
Homeobox protein SIX4

1

20

High-throughput

0.479

High

727607

ING1
Inhibitor of growth protein 1

1

10

High-throughput

0.479

High

727608

RCOR1
REST corepressor 1

1

20

High-throughput

0.479

High

727609

ZN608
Zinc finger protein 608

1

11

High-throughput

0.479

High

727610

PRR12
Proline-rich protein 12

1

20

High-throughput

0.479

High

727611

SOX13
Transcription factor SOX-13

1

20

High-throughput

0.479

High

727612

SATB2
DNA-binding protein SATB2

1

9

High-throughput

0.479

High

727613

RUVB2
RuvB-like 2

1

1

High-throughput

0.479

High

727615

RUVB1
RuvB-like 1

1

1

High-throughput

0.479

High

727617

TR150
Thyroid hormone receptor-associated protein 3

1

5

High-throughput

0.479

High

727618

ZN281
Zinc finger protein 281

1

6

High-throughput

0.479

High

727619

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.479

High

727620

NCOR2
Nuclear receptor corepressor 2

1

20

High-throughput

0.479

High

727621

CABIN
Calcineurin-binding protein cabin-1

1

18

High-throughput

0.479

High

727622

NCOA3
Nuclear receptor coactivator 3

1

19

High-throughput

0.479

High

574939

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.458

High

727485

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.458

High

727509

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.458

High

727588

EPC1
Enhancer of polycomb homolog 1

1

0

High-throughput

0.458

High

727614

POLH
DNA polymerase eta

1

0

High-throughput

0.458

High

727616

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

603117

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

1

High-throughput

0.437

High

727518

GSE1
Genetic suppressor element 1

1

4

High-throughput

0.437

High

727526

QSER1
Glutamine and serine-rich protein 1

1

20

High-throughput

0.437

High

727530

PRC2B
Protein PRRC2B

1

20

High-throughput

0.437

High

727556

PRSR1
Proline and serine-rich protein 1

1

20

High-throughput

0.437

High

727550

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

2

0

High-throughput

0.316

High

727565

OXER1
Oxoeicosanoid receptor 1

2

0

High-throughput

0.316

High

296546

GFPT2
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2

1

0

High-throughput

0.261

Low

574261

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024