Protein: IF4G3
Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII)

Gene: IF4G3, EIF4G3
Organism: Homo sapiens
Interactions: 109
UniProt ID: O43432

Gene Ontology (top 5):
GO:0000339 - RNA cap binding
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

203355

IF4A1
Eukaryotic initiation factor 4A-I

7

20

Small-scale

0.965

High

203361

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

4

9

High-throughput

0.873

High

203371

IF4A2
Eukaryotic initiation factor 4A-II

3

20

High-throughput

0.839

High

203332

IF4E
Eukaryotic translation initiation factor 4E

8

18

Small-scale

0.753

High

198810

RFOX2
RNA binding protein fox-1 homolog 2

3

10

High-throughput

0.667

High

203374

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

3

1

High-throughput

0.667

High

203353

EIF3B
Eukaryotic translation initiation factor 3 subunit B

3

11

Small-scale

0.656

High

203328

ESR1
Estrogen receptor

3

9

High-throughput

0.640

High

203335

PABP1
Polyadenylate-binding protein 1

2

14

Small-scale

0.634

High

203398

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

1

High-throughput

0.628

High

203341

DDX6
Probable ATP-dependent RNA helicase DDX6

1

14

High-throughput

0.618

High

203363

NCBP1
Nuclear cap-binding protein subunit 1

1

4

Small-scale

0.618

High

203384

CMTD1
Catechol O-methyltransferase domain-containing protein 1

3

2

High-throughput

0.609

High

203400

TET5A
Terminal nucleotidyltransferase 5A

2

0

High-throughput

0.602

High

203416

HAOX2
2-Hydroxyacid oxidase 2

2

0

High-throughput

0.602

High

203372

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

2

7

Small-scale

0.601

High

124679

EIF3F
Eukaryotic translation initiation factor 3 subunit F

2

7

High-throughput

0.584

High

176887

EIF3H
Eukaryotic translation initiation factor 3 subunit H

2

8

High-throughput

0.584

High

203391

NF2IP
NFATC2-interacting protein

2

1

High-throughput

0.574

High

203334

HSP7C
Heat shock cognate 71 kDa protein

2

4

High-throughput

0.571

High

203325

PCNT
Pericentrin

1

1

High-throughput

0.541

High

203331

HSPB1
Heat shock protein beta-1

1

2

High-throughput

0.541

High

201643

MSI1H
RNA-binding protein Musashi homolog 1

1

13

High-throughput

0.536

High

203321

HTRA2
Serine protease HTRA2, mitochondrial

1

3

High-throughput

0.536

High

203327

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

203336

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

4

High-throughput

0.536

High

203340

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

2

High-throughput

0.536

High

203343

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.536

High

203344

RL4
Large ribosomal subunit protein uL4

1

2

High-throughput

0.536

High

203346

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

4

High-throughput

0.536

High

203347

PRS6B
26S proteasome regulatory subunit 6B

1

2

High-throughput

0.536

High

203356

1433G
14-3-3 protein gamma

1

9

High-throughput

0.536

High

203362

1433F
14-3-3 protein eta

1

8

High-throughput

0.536

High

203393

PSPC1
Paraspeckle component 1

1

19

High-throughput

0.536

High

203420

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

3

High-throughput

0.536

High

203358

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

203396

THRSP
Thyroid hormone-inducible hepatic protein

1

0

High-throughput

0.513

High

203410

SHRPN
Sharpin

1

0

High-throughput

0.513

High

203351

VAV2
Guanine nucleotide exchange factor VAV2

1

4

High-throughput

0.508

High

203408

MKNK1
MAP kinase-interacting serine/threonine-protein kinase 1

1

5

High-throughput

0.508

High

203333

YES
Tyrosine-protein kinase Yes

1

1

High-throughput

0.501

High

203359

EFNB1
Ephrin-B1

1

2

High-throughput

0.489

High

203376

CTR9
RNA polymerase-associated protein CTR9 homolog

1

4

High-throughput

0.489

High

203378

BTNL9
Butyrophilin-like protein 9

1

1

High-throughput

0.489

High

203386

CRBG2
Beta/gamma crystallin domain-containing protein 2

1

1

High-throughput

0.489

High

203401

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.489

High

203402

TGM7
Protein-glutamine gamma-glutamyltransferase Z

1

2

High-throughput

0.489

High

203403

TCPQM
T-complex protein 1 subunit theta-like 2

1

2

High-throughput

0.489

High

203404

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.489

High

176671

EIF3D
Eukaryotic translation initiation factor 3 subunit D

1

1

High-throughput

0.479

High

203323

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.479

High

203324

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

19

High-throughput

0.479

High

203326

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

3

High-throughput

0.479

High

203337

EZRI
Ezrin

1

3

High-throughput

0.479

High

203338

PRS6A
26S proteasome regulatory subunit 6A

1

8

High-throughput

0.479

High

203342

HS71L
Heat shock 70 kDa protein 1-like

1

4

High-throughput

0.479

High

203345

SYUA
Alpha-synuclein

1

1

High-throughput

0.479

High

203350

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

2

High-throughput

0.479

High

203354

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

1

High-throughput

0.479

High

203357

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

203360

KIF23
Kinesin-like protein KIF23

1

4

High-throughput

0.479

High

203364

TADBP
TAR DNA-binding protein 43

1

15

High-throughput

0.479

High

203365

TIF1B
Transcription intermediary factor 1-beta

1

3

High-throughput

0.479

High

203366

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

5

High-throughput

0.479

High

203367

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

1

4

High-throughput

0.479

High

203368

4EBP2
Eukaryotic translation initiation factor 4E-binding protein 2

1

4

High-throughput

0.479

High

203370

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

9

High-throughput

0.479

High

203373

EEA1
Early endosome antigen 1

1

3

High-throughput

0.479

High

203381

RS27L
Ribosomal protein eS27-like

1

2

High-throughput

0.479

High

203382

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

1

High-throughput

0.479

High

203383

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

203392

NUP43
Nucleoporin Nup43

1

7

High-throughput

0.479

High

203394

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

203397

DAZL
Deleted in azoospermia-like

1

13

High-throughput

0.479

High

203405

NECD
Necdin

1

5

High-throughput

0.479

High

203406

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

2

High-throughput

0.479

High

203407

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

3

High-throughput

0.479

High

203412

4ET
Eukaryotic translation initiation factor 4E transporter

1

1

High-throughput

0.479

High

203417

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

2

High-throughput

0.479

High

203419

ANGE1
Protein angel homolog 1

1

1

High-throughput

0.479

High

203421

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

3

High-throughput

0.479

High

203423

YTHD2
YTH domain-containing family protein 2

1

3

High-throughput

0.479

High

203348

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

203352

BCAT1
Branched-chain-amino-acid aminotransferase, cytosolic

1

0

High-throughput

0.458

High

203414

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.457

High

203379

NBEL2
Neurobeachin-like protein 2

1

5

High-throughput

0.445

High

203422

WDR37
WD repeat-containing protein 37

1

7

Small-scale

0.439

High

203322

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.437

High

203329

MYCN
N-myc proto-oncogene protein

1

5

High-throughput

0.437

High

203330

NTRK1
High affinity nerve growth factor receptor

1

6

High-throughput

0.437

High

203369

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

9

High-throughput

0.437

High

203377

LMBRL
Protein LMBR1L

1

4

High-throughput

0.437

High

203380

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

203390

ARL10
ADP-ribosylation factor-like protein 10

1

3

High-throughput

0.437

High

203395

ESR2
Estrogen receptor beta

1

9

High-throughput

0.437

High

203409

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

2

High-throughput

0.437

High

203411

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.437

High

203413

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

High-throughput

0.437

High

203418

HECD1
E3 ubiquitin-protein ligase HECTD1

1

10

High-throughput

0.437

High

203387

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.407

High

203424

KPTN
KICSTOR complex protein kaptin

3

0

High-throughput

0.347

High

203339

EPHA1
Ephrin type-A receptor 1

2

0

High-throughput

0.328

High

203389

SIGL1
SIGLEC family-like protein 1

2

0

High-throughput

0.328

High

203388

PNKD
Probable hydrolase PNKD

2

0

High-throughput

0.318

High

203375

GPAT3
Glycerol-3-phosphate acyltransferase 3

1

0

High-throughput

0.279

Low

203385

VRK2
Serine/threonine-protein kinase VRK2

1

0

High-throughput

0.279

Low

203399

MR1L1
MORF4 family-associated protein 1-like 1

1

0

High-throughput

0.279

Low

203415

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.279

Low

203349

DNLI4
DNA ligase 4

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024