Protein: KS6B1
Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)

Gene: KS6B1, RPS6KB1
Organism: Homo sapiens
Interactions: 93
UniProt ID: P23443

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0001662 - behavioral fear response
GO:0003009 - skeletal muscle contraction
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

616719

RPTOR
Regulatory-associated protein of mTOR

12

15

Small-scale

0.974

High

616690

EIF3B
Eukaryotic translation initiation factor 3 subunit B

4

4

Small-scale

0.896

High

616683

MK08
Mitogen-activated protein kinase 8

2

20

Small-scale

0.826

High

616729

PDIP3
Polymerase delta-interacting protein 3

2

4

Small-scale

0.815

High

509511

UBL4A
Ubiquitin-like protein 4A

2

14

High-throughput

0.811

High

616676

AKT1
RAC-alpha serine/threonine-protein kinase

3

15

Small-scale

0.799

High

616678

IRS1
Insulin receptor substrate 1

2

11

Small-scale

0.799

High

616672

KS6B1
Ribosomal protein S6 kinase beta-1

2

14

Small-scale

0.778

High

616680

MTOR
Serine/threonine-protein kinase mTOR

24

20

Small-scale

0.767

High

436674

GLI1
Zinc finger protein GLI1

1

5

Small-scale

0.747

High

182084

PDPK1
3-phosphoinositide-dependent protein kinase 1

2

19

Small-scale

0.743

High

452354

PGFRB
Platelet-derived growth factor receptor beta

1

16

Small-scale

0.724

High

616695

CSK2B
Casein kinase II subunit beta

1

7

Small-scale

0.724

High

616731

TBK1
Serine/threonine-protein kinase TBK1

1

20

Small-scale

0.724

High

616692

RS6
Small ribosomal subunit protein eS6

4

10

Small-scale

0.688

High

496317

TAU
Microtubule-associated protein tau

2

16

Small-scale

0.666

High

616701

KPCZ
Protein kinase C zeta type

1

17

Small-scale

0.665

High

616710

PDK1
[Pyruvate dehydrogenase

3

6

Small-scale

0.651

High

433578

LYN
Tyrosine-protein kinase Lyn

1

20

Small-scale

0.647

High

475345

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

10

High-throughput

0.647

High

522780

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.647

High

616681

KSYK
Tyrosine-protein kinase SYK

1

20

Small-scale

0.647

High

616696

ACTS
Actin, alpha skeletal muscle

1

15

Small-scale

0.647

High

616697

CSK21
Casein kinase II subunit alpha

1

20

Small-scale

0.647

High

616702

BTK
Tyrosine-protein kinase BTK

1

20

Small-scale

0.647

High

616711

RHEB
GTP-binding protein Rheb

1

2

Small-scale

0.647

High

124764

EIF3F
Eukaryotic translation initiation factor 3 subunit F

2

4

Small-scale

0.624

High

431542

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

437905

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

616709

SQSTM
Sequestosome-1

1

4

Small-scale

0.618

High

616716

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.618

High

616723

TRIB2
Tribbles homolog 2

1

15

Small-scale

0.618

High

616734

IRS2
Insulin receptor substrate 2

1

11

Small-scale

0.618

High

394134

A4
Amyloid-beta precursor protein

2

11

High-throughput

0.611

High

616728

TRAF4
TNF receptor-associated factor 4

2

8

Small-scale

0.608

High

616715

RICTR
Rapamycin-insensitive companion of mTOR

2

7

Small-scale

0.595

High

616691

CDC42
Cell division control protein 42 homolog

1

11

Small-scale

0.590

High

616706

COASY
Bifunctional coenzyme A synthase

1

2

Small-scale

0.589

High

616694

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

2

5

Small-scale

0.584

High

232782

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

16

Small-scale

0.575

High

616707

PAK1
Serine/threonine-protein kinase PAK 1

1

17

Small-scale

0.575

High

616717

PHLP2
PH domain leucine-rich repeat-containing protein phosphatase 2

1

15

Small-scale

0.575

High

616712

PDCD4
Programmed cell death protein 4

1

3

Small-scale

0.569

High

616687

MXI1
Max-interacting protein 1

1

5

Small-scale

0.561

High

616688

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

6

Small-scale

0.561

High

616705

EP300
Histone acetyltransferase p300

1

14

Small-scale

0.561

High

616725

KAT2B
Histone acetyltransferase KAT2B

1

5

Small-scale

0.561

High

616693

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

Small-scale

0.537

High

616700

MAD1
Max dimerization protein 1

1

5

Small-scale

0.536

High

416932

IF4E
Eukaryotic translation initiation factor 4E

1

1

Small-scale

0.536

High

616689

PPP5
Serine/threonine-protein phosphatase 5

1

14

High-throughput

0.536

High

381125

TBB4A
Tubulin beta-4A chain

1

17

High-throughput

0.515

High

616732

GUAD
Guanine deaminase

1

1

High-throughput

0.515

High

525225

UNG
Uracil-DNA glycosylase

1

1

High-throughput

0.515

High

616675

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

11

High-throughput

0.515

High

616703

APLP2
Amyloid beta precursor like protein 2

1

11

High-throughput

0.515

High

616704

NCBP1
Nuclear cap-binding protein subunit 1

1

0

Small-scale

0.513

High

402816

TETN
Tetranectin

1

2

High-throughput

0.508

High

127632

EF2K
Eukaryotic elongation factor 2 kinase

1

2

Small-scale

0.501

High

265851

NR1I2
Nuclear receptor subfamily 1 group I member 2

1

16

Small-scale

0.501

High

295591

RMP
Unconventional prefoldin RPB5 interactor 1

1

1

Small-scale

0.501

High

616679

GRIA1
Glutamate receptor 1

1

9

Small-scale

0.501

High

616684

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

20

High-throughput

0.501

High

616685

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

4

Small-scale

0.501

High

616733

FBX7
F-box only protein 7

1

4

High-throughput

0.501

High

616698

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

5

Small-scale

0.500

High

616682

KI3L1
Killer cell immunoglobulin-like receptor 3DL1

1

4

High-throughput

0.494

High

616718

DPPA4
Developmental pluripotency-associated protein 4

1

0

High-throughput

0.486

High

153991

TERT
Telomerase reverse transcriptase

1

2

Small-scale

0.479

High

162412

XPO1
Exportin-1

1

6

Small-scale

0.479

High

176945

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

6

Small-scale

0.479

High

317908

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

8

Small-scale

0.479

High

551964

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.479

High

555231

NQO2
Ribosyldihydronicotinamide dehydrogenase [quinone]

1

2

High-throughput

0.479

High

616673

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

9

High-throughput

0.479

High

616677

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.479

High

616699

MDM2
E3 ubiquitin-protein ligase Mdm2

1

6

Small-scale

0.479

High

616708

CTBP1
C-terminal-binding protein 1

1

6

High-throughput

0.479

High

616714

A16L1
Autophagy-related protein 16-1

1

4

High-throughput

0.479

High

616721

BICD2
Protein bicaudal D homolog 2

1

14

High-throughput

0.479

High

616722

RIN2
Ras and Rab interactor 2

1

14

High-throughput

0.479

High

616724

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

616726

BICD1
Protein bicaudal D homolog 1

1

15

High-throughput

0.479

High

616727

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

6

Small-scale

0.479

High

616730

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

616735

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

1

High-throughput

0.479

High

616674

CALX
Calnexin

1

1

High-throughput

0.470

High

616713

IER5
Immediate early response gene 5 protein

1

0

Small-scale

0.458

High

616720

DPTOR
DEP domain-containing mTOR-interacting protein

1

5

Small-scale

0.457

High

159331

PLD2
Phospholipase D2

1

3

Small-scale

0.437

High

329364

AGR2
Anterior gradient protein 2 homolog

1

2

High-throughput

0.437

High

616686

SERPH
Serpin H1

1

6

High-throughput

0.437

High


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Last updated: 15 Jul 2024