Protein: IF2P
Eukaryotic translation initiation factor 5B (eIF-5B) (EC 3.6.5.3) (Translation initiation factor IF-2)

Gene: IF2P, EIF5B
Organism: Homo sapiens
Interactions: 177
UniProt ID: O60841

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0003924 - GTPase activity
GO:0005525 - GTP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

150022

IF1AY
Eukaryotic translation initiation factor 1A, Y-chromosomal

1

5

Small-scale

0.647

High

242763

ECT2
Protein ECT2

2

5

High-throughput

0.620

High

242689

IF6
Eukaryotic translation initiation factor 6

1

2

High-throughput

0.618

High

242722

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

7

High-throughput

0.618

High

242744

ZBT38
Zinc finger and BTB domain-containing protein 38

2

1

High-throughput

0.611

High

242768

C42S1
CDC42 small effector protein 1

2

0

High-throughput

0.602

High

242678

BRCA1
Breast cancer type 1 susceptibility protein

2

4

High-throughput

0.586

High

242731

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.586

High

242743

TTC29
Tetratricopeptide repeat protein 29

2

0

High-throughput

0.585

High

226017

PRKN
E3 ubiquitin-protein ligase parkin

2

6

High-throughput

0.584

High

242622

OBSL1
Obscurin-like protein 1

2

4

High-throughput

0.584

High

242712

SQSTM
Sequestosome-1

2

2

High-throughput

0.584

High

242750

FBXW7
F-box/WD repeat-containing protein 7

2

2

Small-scale

0.584

High

168220

DEGS1
Sphingolipid delta(4)-desaturase DES1

2

0

High-throughput

0.576

High

242639

ESR1
Estrogen receptor

2

8

High-throughput

0.571

High

242696

CSK21
Casein kinase II subunit alpha

1

4

High-throughput

0.569

High

242769

PIHD1
PIH1 domain-containing protein 1

2

0

Small-scale

0.559

High

242665

ETS1
Protein C-ets-1

1

0

High-throughput

0.554

High

242762

ZBTB3
Zinc finger and BTB domain-containing protein 3

1

4

High-throughput

0.541

High

206986

XRCC3
DNA repair protein XRCC3

1

3

High-throughput

0.536

High

242662

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.536

High

242702

FOXK2
Forkhead box protein K2

1

1

High-throughput

0.536

High

242709

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

3

High-throughput

0.536

High

242728

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

3

High-throughput

0.536

High

242739

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.536

High

242619

BRD4
Bromodomain-containing protein 4

2

3

High-throughput

0.533

High

242623

HMMR
Hyaluronan mediated motility receptor

1

2

High-throughput

0.515

High

242719

NUMA1
Nuclear mitotic apparatus protein 1

1

1

High-throughput

0.515

High

217971

PEX1
Peroxisomal ATPase PEX1

1

3

High-throughput

0.515

High

242670

GRN
Progranulin

1

2

High-throughput

0.515

High

242671

T2EB
Transcription initiation factor IIE subunit beta

1

0

High-throughput

0.513

High

242685

HDGF
Hepatoma-derived growth factor

1

0

High-throughput

0.513

High

242699

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.513

High

242725

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

242741

DDX60
Probable ATP-dependent RNA helicase DDX60

1

0

High-throughput

0.513

High

242690

CDC42
Cell division control protein 42 homolog

1

6

High-throughput

0.501

High

242638

FINC
Fibronectin

1

5

High-throughput

0.489

High

242707

FOXD4
Forkhead box protein D4

1

1

High-throughput

0.489

High

242625

WBP4
WW domain-binding protein 4

1

1

High-throughput

0.481

High

242705

TFCP2
Alpha-globin transcription factor CP2

1

2

High-throughput

0.481

High

242746

SRS12
Serine/arginine-rich splicing factor 12

1

2

High-throughput

0.481

High

125036

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

3

High-throughput

0.479

High

148196

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

162252

XPO1
Exportin-1

1

4

High-throughput

0.479

High

209519

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.479

High

213993

SPOP
Speckle-type POZ protein

1

2

High-throughput

0.479

High

232741

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

2

High-throughput

0.479

High

241394

H2B1K
Histone H2B type 1-K

1

3

High-throughput

0.479

High

242624

CISY
Citrate synthase, mitochondrial

1

2

High-throughput

0.479

High

242627

RNF8
E3 ubiquitin-protein ligase RNF8

1

6

High-throughput

0.479

High

242628

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.479

High

242630

UBR5
E3 ubiquitin-protein ligase UBR5

1

4

High-throughput

0.479

High

242631

HERC2
E3 ubiquitin-protein ligase HERC2

1

5

High-throughput

0.479

High

242632

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

3

High-throughput

0.479

High

242635

EGFR
Epidermal growth factor receptor

1

3

High-throughput

0.479

High

242636

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.479

High

242637

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

1

High-throughput

0.479

High

242640

GCR
Glucocorticoid receptor

1

7

High-throughput

0.479

High

242644

P53
Cellular tumor antigen p53

1

2

Small-scale

0.479

High

242646

RLA2
Large ribosomal subunit protein P2

1

1

High-throughput

0.479

High

242652

NFM
Neurofilament medium polypeptide

1

1

High-throughput

0.479

High

242653

HS90A
Heat shock protein HSP 90-alpha

1

6

High-throughput

0.479

High

242655

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

1

High-throughput

0.479

High

242656

VIME
Vimentin

1

1

High-throughput

0.479

High

242657

ANXA5
Annexin A5

1

1

High-throughput

0.479

High

242658

HMGB1
High mobility group protein B1

1

7

High-throughput

0.479

High

242659

F16P1
Fructose-1,6-bisphosphatase 1

1

1

High-throughput

0.479

High

242661

H14
Histone H1.4

1

1

High-throughput

0.479

High

242664

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

242667

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

242668

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.479

High

242669

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

242672

PDIA3
Protein disulfide-isomerase A3

1

1

High-throughput

0.479

High

242673

1433S
14-3-3 protein sigma

1

9

Small-scale

0.479

High

242674

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

242675

PHB1
Prohibitin 1

1

2

High-throughput

0.479

High

242677

SYUA
Alpha-synuclein

1

2

High-throughput

0.479

High

242679

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

242682

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

1

High-throughput

0.479

High

242684

F10A1
Hsc70-interacting protein

1

4

High-throughput

0.479

High

242686

RM12
Large ribosomal subunit protein bL12m

1

4

High-throughput

0.479

High

242687

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

1

High-throughput

0.479

High

242688

NP1L1
Nucleosome assembly protein 1-like 1

1

3

High-throughput

0.479

High

242691

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

2

High-throughput

0.479

High

242693

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

242694

RL7A
Large ribosomal subunit protein eL8

1

3

High-throughput

0.479

High

242700

CDK5
Cyclin-dependent kinase 5

1

5

High-throughput

0.479

High

242701

HSF1
Heat shock factor protein 1

1

2

High-throughput

0.479

High

242703

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

242706

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

8

High-throughput

0.479

High

242708

NFX1
Transcriptional repressor NF-X1

1

2

High-throughput

0.479

High

242711

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

242714

CUL3
Cullin-3

1

7

High-throughput

0.479

High

242717

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

5

High-throughput

0.479

High

242720

CUL7
Cullin-7

1

4

High-throughput

0.479

High

242721

TNIP1
TNFAIP3-interacting protein 1

1

7

High-throughput

0.479

High

242723

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

242726

SMAD2
Mothers against decapentaplegic homolog 2

1

4

High-throughput

0.479

High

242729

RC3H1
Roquin-1

1

3

High-throughput

0.479

High

242733

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

242740

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.479

High

242747

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

242748

NELL1
Protein kinase C-binding protein NELL1

1

1

Small-scale

0.479

High

242749

FGF11
Fibroblast growth factor 11

1

1

High-throughput

0.479

High

242756

DNJC2
DnaJ homolog subfamily C member 2

1

6

High-throughput

0.479

High

242758

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

High-throughput

0.479

High

242759

TRI31
E3 ubiquitin-protein ligase TRIM31

1

3

High-throughput

0.479

High

242761

RHOJ
Rho-related GTP-binding protein RhoJ

1

6

High-throughput

0.479

High

242764

RC3H2
Roquin-2

1

4

High-throughput

0.479

High

242765

BRD7
Bromodomain-containing protein 7

1

4

High-throughput

0.479

High

242766

ANLN
Anillin

1

1

High-throughput

0.479

High

242767

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

3

High-throughput

0.479

High

242772

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

3

High-throughput

0.479

High

242774

HDAC6
Histone deacetylase 6

1

5

High-throughput

0.479

High

242775

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

242776

FZR1
Fizzy-related protein homolog

1

2

High-throughput

0.479

High

242633

AGR2
Anterior gradient protein 2 homolog

1

2

High-throughput

0.470

High

242663

THB
Thyroid hormone receptor beta

1

8

High-throughput

0.470

High

182478

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

210423

ZN207
BUB3-interacting and GLEBS motif-containing protein ZNF207

1

0

High-throughput

0.458

High

233096

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

242621

CPNE3
Copine-3

1

0

High-throughput

0.458

High

242629

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

242649

ENOA
Alpha-enolase

1

0

High-throughput

0.458

High

242650

PYGL
Glycogen phosphorylase, liver form

1

0

High-throughput

0.458

High

242651

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

242680

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.458

High

242695

RS21
Small ribosomal subunit protein eS21

1

0

High-throughput

0.458

High

242715

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

High-throughput

0.458

High

242727

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

242730

IFIX
Pyrin and HIN domain-containing protein 1

1

0

High-throughput

0.458

High

242735

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

High-throughput

0.458

High

242736

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

242737

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

242738

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

242742

CMTR1
Cap-specific mRNA

1

0

High-throughput

0.458

High

242745

CA131
Uncharacterized protein C1orf131

1

0

High-throughput

0.458

High

242752

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.458

High

242753

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

242754

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

242760

RWDD1
RWD domain-containing protein 1

1

0

High-throughput

0.458

High

242771

PLK2
Serine/threonine-protein kinase PLK2

1

0

High-throughput

0.458

High

242773

CRNN
Cornulin

1

0

High-throughput

0.458

High

242778

PA2G4
Proliferation-associated protein 2G4

1

0

High-throughput

0.458

High

242779

TIM9
Mitochondrial import inner membrane translocase subunit Tim9

1

0

High-throughput

0.458

High

242697

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

1

1

Small-scale

0.457

High

173801

MK13
Mitogen-activated protein kinase 13

1

8

Small-scale

0.445

High

242647

JUN
Transcription factor Jun

1

3

High-throughput

0.445

High

242704

NCBP1
Nuclear cap-binding protein subunit 1

1

1

High-throughput

0.445

High

242713

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.445

High

242716

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

1

High-throughput

0.445

High

242755

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.445

High

242734

PAXI1
PAX-interacting protein 1

1

1

High-throughput

0.439

High

242692

STXB1
Syntaxin-binding protein 1

1

0

High-throughput

0.438

High

242620

LIRB5
Leukocyte immunoglobulin-like receptor subfamily B member 5

1

1

High-throughput

0.437

High

242641

MYCN
N-myc proto-oncogene protein

1

5

High-throughput

0.437

High

242643

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.437

High

242660

H2A1
Histone H2A type 1

1

5

High-throughput

0.437

High

242666

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

242676

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

242681

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.437

High

242710

CBX3
Chromobox protein homolog 3

1

1

High-throughput

0.437

High

242724

BRD3
Bromodomain-containing protein 3

1

3

High-throughput

0.437

High

242732

LRC31
Leucine-rich repeat-containing protein 31

1

2

High-throughput

0.437

High

242751

H2B1A
Histone H2B type 1-A

1

3

High-throughput

0.437

High

242757

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

1

High-throughput

0.437

High

242770

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.437

High

242777

TRI33
E3 ubiquitin-protein ligase TRIM33

1

4

High-throughput

0.437

High

242634

PAK4
Serine/threonine-protein kinase PAK 4

1

0

High-throughput

0.426

High

242642

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

0

High-throughput

0.426

High

242648

RB
Retinoblastoma-associated protein

1

0

High-throughput

0.426

High

242718

BECN1
Beclin-1

1

0

High-throughput

0.426

High

242645

IPSP
Plasma serine protease inhibitor

1

1

Small-scale

0.407

High

242698

CBX1
Chromobox protein homolog 1

1

1

Small-scale

0.407

High

242683

CEBPA
CCAAT/enhancer-binding protein alpha

1

3

High-throughput

0.373

High

242626

WFS1
Wolframin

1

0

High-throughput

0.268

Low

242654

RU2B
U2 small nuclear ribonucleoprotein B''

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024