Protein: Q921K2
Poly [ADP-ribose] polymerase (EC 2.4.2.30)

Gene: Q921K2, Parp1
Organism: Mus musculus
Interactions: 25
UniProt ID: Q921K2

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003684 - damaged DNA binding
GO:0003950 - NAD+ ADP-ribosyltransferase activity
GO:0005635 - nuclear envelope

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

250436

AURKB
Aurora kinase B

1

7

Small-scale

0.589

High

590478

PO5F1
POU domain, class 5, transcription factor 1

2

6

High-throughput

0.584

High

818753

SOX2
Transcription factor SOX-2

2

20

Small-scale

0.584

High

1257481

UHRF1
E3 ubiquitin-protein ligase UHRF1

2

15

Small-scale

0.584

High

872339

FAF1
FAS-associated factor 1

1

4

Small-scale

0.561

High

139838

OGG1
N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase

1

0

Small-scale

0.537

High

936916

CASP3
Caspase-3

1

9

Small-scale

0.501

High

653471

CENPB
Major centromere autoantigen B

1

3

High-throughput

0.481

High

139469

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

9

High-throughput

0.479

High

476952

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

7

Small-scale

0.479

High

533919

DNMT1
DNA

1

8

Small-scale

0.479

High

886506

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

2

Small-scale

0.479

High

1142623

E2F1
Transcription factor E2F1

1

5

Small-scale

0.479

High

1144925

TFE3
Transcription factor E3

1

7

High-throughput

0.479

High

1186600

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

4

High-throughput

0.479

High

1193917

FACD2
Fanconi anemia group D2 protein homolog

1

2

High-throughput

0.479

High

1194663

NANOG
Homeobox protein NANOG

1

7

High-throughput

0.479

High

1265378

EED
Polycomb protein EED

1

9

High-throughput

0.479

High

1265716

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

7

Small-scale

0.479

High

1111330

STING
Stimulator of interferon genes protein

1

2

High-throughput

0.445

High

1159856

ABCF1
ATP-binding cassette sub-family F member 1

1

4

High-throughput

0.445

High

1265715

CDK9
Cyclin-dependent kinase 9

1

13

Small-scale

0.445

High

1112351

OTUD5
OTU domain-containing protein 5

1

6

Small-scale

0.437

High

222573

ITB3
Integrin beta-3

1

0

High-throughput

0.261

Low

558927

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024