Protein: FADD
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity)

Gene: FADD
Organism: Mus musculus
Interactions: 22
UniProt ID: Q61160

Gene Ontology (top 5):
GO:0001822 - kidney development
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0002020 - protease binding
GO:0002821 - positive regulation of adaptive immune response
GO:0005123 - death receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1141524

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

14

20

Small-scale

0.978

High

292700

CASP8
Caspase-8

10

17

Small-scale

0.970

High

1142224

RIPK3
Receptor-interacting serine/threonine-protein kinase 3

6

18

Small-scale

0.931

High

632465

TNR6
Tumor necrosis factor receptor superfamily member 6

4

20

Small-scale

0.881

High

193423

CFLAR
CASP8 and FADD-like apoptosis regulator

2

17

Small-scale

0.776

High

1142218

ATG5
Autophagy protein 5

2

4

Small-scale

0.621

High

140029

BIRC3
Baculoviral IAP repeat-containing protein 3

1

17

Small-scale

0.618

High

607555

MYD88
Myeloid differentiation primary response protein MyD88

1

7

Small-scale

0.618

High

626862

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

20

Small-scale

0.618

High

1130111

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

Small-scale

0.618

High

1142214

IRAK1
Interleukin-1 receptor-associated kinase 1

1

2

Small-scale

0.618

High

1142216

IRAK2
Interleukin-1 receptor-associated kinase-like 2

1

2

Small-scale

0.618

High

1142222

HIPK3
Homeodomain-interacting protein kinase 3

1

6

Small-scale

0.618

High

1142223

PIDD1
p53-induced death domain-containing protein 1

1

5

Small-scale

0.618

High

995661

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

4

Small-scale

0.561

High

1142215

A16L1
Autophagy-related protein 16-1

1

2

Small-scale

0.536

High

1142219

ATG12
Ubiquitin-like protein ATG12

1

1

Small-scale

0.515

High

420403

TNFA
Tumor necrosis factor

1

15

Small-scale

0.479

High

1141356

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

11

Small-scale

0.479

High

1142220

MLKL
Mixed lineage kinase domain-like protein

1

6

Small-scale

0.479

High

1142221

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

1

Small-scale

0.479

High

1142217

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

13

Small-scale

0.437

High


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Last updated: 15 Jul 2024