Protein: BECN1
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]

Gene: BECN1
Organism: Mus musculus
Interactions: 28
UniProt ID: O88597

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000407 - phagophore assembly site
GO:0000423 - mitophagy
GO:0001525 - angiogenesis
GO:0001666 - response to hypoxia

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

291950

BCL2
Apoptosis regulator Bcl-2

7

8

Small-scale

0.958

High

291960

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

6

7

Small-scale

0.724

High

291965

BAKOR
Beclin 1-associated autophagy-related key regulator

3

2

Small-scale

0.634

High

291968

PI3R4
Phosphoinositide 3-kinase regulatory subunit 4

3

4

Small-scale

0.624

High

291949

BECN1
Beclin-1

1

2

Small-scale

0.618

High

291959

B2CL1
Bcl-2-like protein 1

1

9

Small-scale

0.618

High

291973

PRKN
E3 ubiquitin-protein ligase parkin

2

3

Small-scale

0.584

High

291964

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

1

Small-scale

0.573

High

291961

RUBIC
Run domain Beclin-1-interacting and cysteine-rich domain-containing protein

2

3

Small-scale

0.571

High

291966

UVRAG
UV radiation resistance-associated protein

2

3

Small-scale

0.552

High

291967

NRBF2
Nuclear receptor-binding factor 2

1

1

Small-scale

0.536

High

291951

MYD88
Myeloid differentiation primary response protein MyD88

1

1

Small-scale

0.515

High

291952

CXA1
Gap junction alpha-1 protein

1

1

Small-scale

0.500

High

291953

HMGB1
High mobility group protein B1

1

2

Small-scale

0.500

High

291962

TCAM1
TIR domain-containing adapter molecule 1

1

0

Small-scale

0.493

High

291971

TLR4
Toll-like receptor 4

1

0

Small-scale

0.493

High

291954

TRAF6
TNF receptor-associated factor 6

1

3

Small-scale

0.479

High

291955

DAB2
Disabled homolog 2

1

1

Small-scale

0.479

High

291957

HSPB6
Heat shock protein beta-6

1

3

Small-scale

0.479

High

291958

GRID2
Glutamate receptor ionotropic, delta-2

1

1

Small-scale

0.479

High

291970

SHLB1
Endophilin-B1

1

3

Small-scale

0.479

High

222621

B2L11
Bcl-2-like protein 11

1

0

Small-scale

0.458

High

140053

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

4

High-throughput

0.457

High

291969

ASC
Apoptosis-associated speck-like protein containing a CARD

1

8

Small-scale

0.445

High

291972

SLAF1
Signaling lymphocytic activation molecule

1

1

Small-scale

0.445

High

291956

TAB3
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3

1

2

Small-scale

0.439

High

291963

ZBT24
Zinc finger and BTB domain-containing protein 24

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024