Protein: INSR
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]

Gene: INSR
Organism: Mus musculus
Interactions: 24
UniProt ID: P15208

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0001933 - negative regulation of protein phosphorylation
GO:0001934 - positive regulation of protein phosphorylation
GO:0002092 - positive regulation of receptor internalization
GO:0003007 - heart morphogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

546274

GRB10
Growth factor receptor-bound protein 10

2

20

Small-scale

0.786

High

546279

SH2B2
SH2B adapter protein 2

2

20

Small-scale

0.754

High

403410

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.691

High

546263

AKT1
RAC-alpha serine/threonine-protein kinase

1

18

Small-scale

0.691

High

546269

DOK1
Docking protein 1

1

20

Small-scale

0.621

High

193338

SOCS1
Suppressor of cytokine signaling 1

1

20

Small-scale

0.618

High

291359

SORL
Sortilin-related receptor

1

20

Small-scale

0.618

High

546262

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

Small-scale

0.618

High

546265

IRS1
Insulin receptor substrate 1

1

20

Small-scale

0.618

High

546273

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

13

Small-scale

0.618

High

546275

SRBS1
Sorbin and SH3 domain-containing protein 1

1

20

Small-scale

0.618

High

546277

SNX9
Sorting nexin-9

1

20

Small-scale

0.618

High

546264

RAB24
Ras-related protein Rab-24

1

20

High-throughput

0.575

High

546276

RAB34
Ras-related protein Rab-34

1

20

High-throughput

0.575

High

546266

CAV1
Caveolin-1

2

9

Small-scale

0.571

High

193373

SOCS3
Suppressor of cytokine signaling 3

1

20

Small-scale

0.553

High

546278

ARRB2
Beta-arrestin-2

1

3

Small-scale

0.536

High

546280

DOK3
Docking protein 3

1

20

Small-scale

0.481

High

140081

FLOT1
Flotillin-1

1

14

Small-scale

0.479

High

546267

CAV3
Caveolin-3

1

9

Small-scale

0.479

High

546270

PLAK
Junction plakoglobin

1

20

Small-scale

0.479

High

546272

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.458

High

546271

TRI72
Tripartite motif-containing protein 72

1

4

Small-scale

0.457

High

546268

ASM3B
Acid sphingomyelinase-like phosphodiesterase 3b

1

1

Small-scale

0.445

High


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Last updated: 15 Jul 2024