HitPredict
Protein: CFLAR
CASP8 and FADD-like apoptosis regulator (Caspase homolog) (CASH) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (Cellular FLICE-like inhibitory protein) (c-FLIP) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Inhibitor of FLICE) (I-FLICE) (MACH-related inducer of toxicity) (MRIT) (Usurpin) [Cleaved into: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12]

Gene: CFLAR
Organism: Mus musculus
Interactions: 9
UniProt ID: O35732

Gene Ontology (top 5):
GO:0002020 - protease binding
GO:0005123 - death receptor binding
GO:0005737 - cytoplasm
GO:0006508 - proteolysis
GO:0006915 - apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score		 Confidence

193423

 FADD
FAS-associated death domain protein

2

17

Small-scale

 0.776

High

193419

 CASP8
Caspase-8

1

18

Small-scale

 0.618

High

193420

 MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

11

Small-scale

 0.618

High

193422

 MP2K4
Dual specificity mitogen-activated protein kinase kinase 4

1

11

Small-scale

 0.618

High

193425

 MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

9

Small-scale

 0.618

High

193424

 ITCH
E3 ubiquitin-protein ligase Itchy

1

3

Small-scale

 0.527

High

140204

 HDAC1
Histone deacetylase 1

1

6

Small-scale

 0.479

High

193418

 HDAC3
Histone deacetylase 3

1

1

Small-scale

 0.479

High

193421

 TNFL6
Tumor necrosis factor ligand superfamily member 6

1

13

Small-scale

 0.479

High

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Last updated: 15 Jul 2024