Protein: IL6
Interleukin-6 (IL-6) (B-cell hybridoma growth factor) (Interleukin HP-1)

Gene: IL6
Organism: Mus musculus
Interactions: 19
UniProt ID: P08505

Gene Ontology (top 5):
GO:0001781 - neutrophil apoptotic process
GO:0002262 - myeloid cell homeostasis
GO:0002314 - germinal center B cell differentiation
GO:0002639 - positive regulation of immunoglobulin production
GO:0005102 - signaling receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

439911

TF65
Transcription factor p65

11

4

Small-scale

0.751

High

439910

IL6RB
Interleukin-6 receptor subunit beta

1

1

Small-scale

0.646

High

439903

NFKB1
Nuclear factor NF-kappa-B p105 subunit

3

6

Small-scale

0.640

High

439916

IKBZ
NF-kappa-B inhibitor zeta

3

3

Small-scale

0.640

High

439914

ATF3
Cyclic AMP-dependent transcription factor ATF-3

2

2

Small-scale

0.584

High

439906

CEBPG
CCAAT/enhancer-binding protein gamma

2

4

Small-scale

0.533

High

140215

HDAC1
Histone deacetylase 1

1

1

Small-scale

0.479

High

404103

JUN
Transcription factor Jun

1

1

Small-scale

0.479

High

439902

JUNB
Transcription factor JunB

1

2

Small-scale

0.479

High

439904

CEBPB
CCAAT/enhancer-binding protein beta

1

4

Small-scale

0.479

High

439908

HDAC2
Histone deacetylase 2

1

1

Small-scale

0.479

High

439912

TET2
Methylcytosine dioxygenase TET2

1

1

Small-scale

0.479

High

439917

IKBA
NF-kappa-B inhibitor alpha

1

3

Small-scale

0.479

High

192747

XBP1
X-box-binding protein 1

1

0

Small-scale

0.458

High

439905

BCL6
B-cell lymphoma 6 protein homolog

1

0

Small-scale

0.458

High

439907

1433G
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]

1

1

Small-scale

0.437

High

439915

1433B
14-3-3 protein beta/alpha

1

1

Small-scale

0.437

High

439909

ELAV1
ELAV-like protein 1

1

0

Small-scale

0.249

Low

439913

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024