Protein: IRF1
Interferon regulatory factor 1 (IRF-1)

Gene: IRF1
Organism: Mus musculus
Interactions: 38
UniProt ID: P15314

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

547380

IRF8
Interferon regulatory factor 8

5

16

Small-scale

0.910

High

547382

NOS2
Nitric oxide synthase, inducible

7

1

Small-scale

0.736

High

547383

CCL5
C-C motif chemokine 5

4

10

Small-scale

0.683

High

547379

MYD88
Myeloid differentiation primary response protein MyD88

3

20

Small-scale

0.650

High

547381

NFKB1
Nuclear factor NF-kappa-B p105 subunit

3

18

Small-scale

0.640

High

547388

IL12B
Interleukin-12 subunit beta

3

8

Small-scale

0.640

High

547395

C2TA
MHC class II transactivator

3

7

Small-scale

0.640

High

547399

IRF9
Interferon regulatory factor 9

1

16

Small-scale

0.618

High

547397

PGH2
Prostaglandin G/H synthase 2

2

1

Small-scale

0.612

High

547392

SUMO1
Small ubiquitin-related modifier 1

2

6

Small-scale

0.606

High

547387

IL12A
Interleukin-12 subunit alpha

2

7

Small-scale

0.601

High

547396

TF65
Transcription factor p65

2

20

Small-scale

0.598

High

547390

STAT6
Signal transducer and transcription activator 6

2

20

Small-scale

0.584

High

222288

PIAS3
E3 SUMO-protein ligase PIAS3

1

3

Small-scale

0.573

High

547393

UBC9
SUMO-conjugating enzyme UBC9

1

4

Small-scale

0.549

High

547403

IL27A
Interleukin-27 subunit alpha

2

3

Small-scale

0.549

High

547406

IL23A
Interleukin-23 subunit alpha

1

2

Small-scale

0.515

High

547408

TBK1
Serine/threonine-protein kinase TBK1

1

14

Small-scale

0.501

High

140220

HDAC1
Histone deacetylase 1

1

5

Small-scale

0.479

High

193340

SOCS1
Suppressor of cytokine signaling 1

1

7

Small-scale

0.479

High

420386

TNFA
Tumor necrosis factor

1

7

Small-scale

0.479

High

547384

AGTR2
Type-2 angiotensin II receptor

1

2

Small-scale

0.479

High

547385

STAT3
Signal transducer and activator of transcription 3

1

20

Small-scale

0.479

High

547386

STA5A
Signal transducer and activator of transcription 5A

1

20

Small-scale

0.479

High

547394

IL18
Interleukin-18

1

1

Small-scale

0.479

High

547400

RSAD2
S-adenosylmethionine-dependent nucleotide dehydratase RSAD2

1

2

Small-scale

0.479

High

547401

GBP5
Guanylate-binding protein 5

1

9

Small-scale

0.479

High

547404

FOXP3
Forkhead box protein P3

1

4

Small-scale

0.479

High

547405

TLR3
Toll-like receptor 3

1

13

Small-scale

0.479

High

547407

TLR9
Toll-like receptor 9

1

13

Small-scale

0.479

High

547409

GBP2
Guanylate-binding protein 2

1

9

Small-scale

0.479

High

444952

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.458

High

547389

IL15
Interleukin-15

1

0

Small-scale

0.458

High

547391

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

Small-scale

0.458

High

547377

LYAM1
L-selectin

1

2

Small-scale

0.437

High

547378

TAP1
Antigen peptide transporter 1

1

3

Small-scale

0.437

High

547398

I12R1
Interleukin-12 receptor subunit beta-1

1

3

Small-scale

0.437

High

547402

C1RA
Complement C1r-A subcomponent

1

1

Small-scale

0.437

High


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Last updated: 15 Jul 2024