Protein: SPT2
Protein SPT2 (Negative regulator of Ty transcription)

Gene: SPT2
Organism: Saccharomyces cerevisiae S288C
Interactions: 66
UniProt ID: P06843

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000217 - DNA secondary structure binding
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

420541

CSK21
Casein kinase II subunit alpha

2

1

Small-scale

0.639

High

420548

CSK22
Casein kinase II subunit alpha'

2

1

Small-scale

0.639

High

420572

CSK2B
Casein kinase II subunit beta

2

1

Small-scale

0.611

High

420579

IMA1
Importin subunit alpha

2

0

High-throughput

0.595

High

420586

HIF1
HAT1-interacting factor 1

2

0

Small-scale

0.576

High

420573

MCM6
DNA replication licensing factor MCM6

2

0

Small-scale

0.570

High

420571

SGN1
RNA-binding protein SGN1

1

1

High-throughput

0.536

High

420539

ERF1
Eukaryotic peptide chain release factor subunit 1

1

0

High-throughput

0.513

High

420540

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.513

High

420551

NPR1
Nitrogen permease reactivator protein

1

0

High-throughput

0.513

High

420555

XPO1
Exportin-1

1

0

High-throughput

0.513

High

420559

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.513

High

420561

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.513

High

420563

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

0

High-throughput

0.513

High

420564

SSF1
Ribosome biogenesis protein SSF1

1

0

High-throughput

0.513

High

420567

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.513

High

420570

UTP7
U3 small nucleolar RNA-associated protein 7

1

0

High-throughput

0.513

High

420574

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.513

High

420575

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.513

High

420580

RLI1
Translation initiation factor RLI1

1

0

High-throughput

0.513

High

420582

PUF6
Pumilio homology domain family member 6

1

0

High-throughput

0.513

High

420583

STE23
A-factor-processing enzyme

1

0

High-throughput

0.513

High

420584

NOP12
Nucleolar protein 12

1

0

High-throughput

0.513

High

341876

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.500

High

420529

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

High-throughput

0.500

High

420536

SSBP1
Single-stranded nucleic acid-binding protein

1

1

High-throughput

0.500

High

420545

ADT3
ADP,ATP carrier protein 3

1

1

High-throughput

0.489

High

140755

FOB1
DNA replication fork-blocking protein FOB1

1

0

High-throughput

0.486

High

420581

GCN5
Histone acetyltransferase GCN5

1

0

Small-scale

0.480

High

367611

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.479

High

376582

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.479

High

420544

HXKG
Glucokinase-1

1

0

High-throughput

0.479

High

420550

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.479

High

420554

BMH1
Protein BMH1

1

0

High-throughput

0.479

High

420577

ACT
Actin

1

0

High-throughput

0.479

High

420565

CSK2C
Casein kinase II subunit beta'

1

1

Small-scale

0.479

High

420558

BRR2
Pre-mRNA-splicing helicase BRR2

1

0

Small-scale

0.460

High

141055

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

420528

SPT2
Protein SPT2

1

0

Small-scale

0.458

High

420530

SWI1
SWI/SNF chromatin-remodeling complex subunit SWI1

1

0

Small-scale

0.458

High

420533

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

420534

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

420535

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

420547

SNF6
Transcription regulatory protein SNF6

1

0

Small-scale

0.458

High

420552

SPT6
Transcription elongation factor SPT6

1

0

Small-scale

0.458

High

420553

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

420556

ASF1
Histone chaperone ASF1

1

0

Small-scale

0.458

High

420560

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

420576

SNF12
Transcription regulatory protein SNF12

1

0

Small-scale

0.458

High

420578

REG1
Resistance to glucose repression protein 1

1

0

Small-scale

0.458

High

420585

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

420546

ADT2
ADP,ATP carrier protein 2

1

1

High-throughput

0.457

High

420537

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

420538

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

420542

CDC23
Anaphase-promoting complex subunit CDC23

2

0

Small-scale

0.330

High

420568

SAP1
Protein SAP1

1

0

Small-scale

0.299

High

420557

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.279

Low

420562

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.279

Low

420566

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.279

Low

420569

FIR1
Factor interacting with REF2

1

0

Small-scale

0.261

Low

420531

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.261

Low

420543

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

0

High-throughput

0.261

Low

409874

CDC37
Hsp90 co-chaperone Cdc37

1

0

Small-scale

0.251

Low

420549

PMA2
Plasma membrane ATPase 2

1

0

High-throughput

0.249

Low

420532

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024