Protein: GRR1
SCF E3 ubiquitin ligase complex F-box protein GRR1 (F-box and leucine-rich repeat protein GRR1) (F-box/LRR-repeat protein GRR1)

Gene: GRR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 71
UniProt ID: P24814

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000142 - cellular bud neck contractile ring
GO:0000209 - protein polyubiquitination
GO:0000751 - mitotic cell cycle G1 arrest in response to pheromone
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

624307

SKP1
Suppressor of kinetochore protein 1

20

20

Small-scale

0.991

High

624323

CDC53
Cell division control protein 53

12

19

Small-scale

0.980

High

593379

CG12
G1/S-specific cyclin CLN2

10

3

Small-scale

0.755

High

593358

CG11
G1/S-specific cyclin CLN1

4

2

Small-scale

0.694

High

624320

RBX1
RING-box protein HRT1

4

5

Small-scale

0.690

High

339456

CDK1
Cyclin-dependent kinase 1

3

0

Small-scale

0.623

High

624327

6P22
6-phosphofructo-2-kinase 2

3

0

Small-scale

0.619

High

477142

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

10

High-throughput

0.618

High

624316

CYK2
Cytokinesis protein 2

2

3

Small-scale

0.611

High

624276

CDC48
Cell division control protein 48

2

2

High-throughput

0.594

High

624282

TYE7
Transcription factor TYE7

2

0

Small-scale

0.569

High

624287

SRL3
Protein SRL3

2

0

Small-scale

0.559

High

624305

CTH2
mRNA decay factor CTH2

2

0

Small-scale

0.559

High

624284

BMH2
Protein BMH2

1

9

Small-scale

0.552

High

624283

MKS1
Negative regulator of RAS-cAMP pathway

1

0

Small-scale

0.537

High

389852

VDAC1
Mitochondrial outer membrane protein porin 1

1

3

High-throughput

0.536

High

540531

CYPH
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.536

High

560441

PDC5
Pyruvate decarboxylase isozyme 2

1

1

High-throughput

0.536

High

562186

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

1

High-throughput

0.536

High

624277

PDC6
Pyruvate decarboxylase isozyme 3

1

1

High-throughput

0.536

High

624295

SAHH
Adenosylhomocysteinase

1

1

High-throughput

0.536

High

624310

REG1
Resistance to glucose repression protein 1

1

0

Small-scale

0.529

High

624315

GIS4
Protein GIS4

1

0

Small-scale

0.529

High

539444

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

1

6

High-throughput

0.515

High

355790

H2B2
Histone H2B.2

1

0

High-throughput

0.513

High

624280

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

0

High-throughput

0.513

High

624306

GCH1
GTP cyclohydrolase 1

1

0

High-throughput

0.513

High

624312

COFI
Cofilin

1

0

High-throughput

0.513

High

624297

MED3
Mediator of RNA polymerase II transcription subunit 3

1

0

Small-scale

0.504

High

562326

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

1

High-throughput

0.500

High

624290

BZZ1
Protein BZZ1

1

0

High-throughput

0.486

High

381425

GAL1
Galactokinase

1

0

High-throughput

0.479

High

624289

STP2
Transcription factor STP2

1

1

Small-scale

0.479

High

624291

YHT1
PH domain-containing protein YHR131C

1

1

Small-scale

0.479

High

624311

STP1
Transcription factor STP1

1

1

Small-scale

0.479

High

624288

SHE3
SWI5-dependent HO expression protein 3

1

0

Small-scale

0.460

High

624313

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

1

0

Small-scale

0.460

High

624321

DSE3
Protein DSE3

1

0

Small-scale

0.460

High

624326

CSN10
COP9 signalosome complex subunit 10

1

0

Small-scale

0.460

High

526782

CG13
G1/S-specific cyclin CLN3

1

0

Small-scale

0.458

High

624279

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

624281

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

624286

YK25
Uncharacterized protein YKR045C

1

0

Small-scale

0.458

High

624302

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

624304

BUD4
Bud site selection protein 4

1

0

Small-scale

0.458

High

624314

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

624322

NDD1
Nuclear division defective protein 1

1

0

Small-scale

0.458

High

624324

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

624325

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

624328

SFG1
Superficial pseudohyphal growth protein 1

1

0

Small-scale

0.458

High

624303

TCPQ
T-complex protein 1 subunit theta

1

3

High-throughput

0.445

High

624318

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

2

High-throughput

0.445

High

624293

TCPG
T-complex protein 1 subunit gamma

1

2

High-throughput

0.437

High

624309

YNO4
Uncharacterized protein YNL144C

1

1

Small-scale

0.437

High

624317

GIC2
GTPase-interacting component 2

2

0

Small-scale

0.306

High

624285

MTH1
Protein MTH1

2

0

Small-scale

0.305

High

624292

SSN2
Mediator of RNA polymerase II transcription subunit 13

2

0

Small-scale

0.304

High

342347

CISY1
Citrate synthase, mitochondrial

1

0

High-throughput

0.261

Low

520790

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.261

Low

520919

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.261

Low

583197

METK2
S-adenosylmethionine synthase 2

1

0

High-throughput

0.261

Low

624300

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

0

High-throughput

0.261

Low

624319

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.261

Low

140765

FOB1
DNA replication fork-blocking protein FOB1

1

0

Small-scale

0.251

Low

624298

YIT6
Uncharacterized protein YIR016W

1

0

Small-scale

0.251

Low

624301

SSY5
SPS-sensor serine protease component SSY5

1

0

Small-scale

0.251

Low

624278

GAC1
Serine/threonine-protein phosphatase 1 regulatory subunit GAC1

1

0

Small-scale

0.249

Low

624294

NPR2
Nitrogen permease regulator 2

1

0

Small-scale

0.249

Low

624296

FIR1
Factor interacting with REF2

1

0

Small-scale

0.249

Low

624299

SBE2
Protein SBE2

1

0

Small-scale

0.249

Low

624308

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024