Protein: BNI1
Protein BNI1 (Pointed projection formation protein 3) (Sensitive to high expression protein 5) (Synthetic lethal 39)

Gene: BNI1
Organism: Saccharomyces cerevisiae S288C
Interactions: 240
UniProt ID: P41832

Gene Ontology (top 5):
GO:0000131 - incipient cellular bud site
GO:0000132 - establishment of mitotic spindle orientation
GO:0000133 - polarisome
GO:0003779 - actin binding
GO:0005522 - profilin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

784605

BNI1
Protein BNI1

6

13

Small-scale

0.939

High

580322

CDC42
Cell division control protein 42

5

20

Small-scale

0.919

High

784637

ACT
Actin

4

18

Small-scale

0.885

High

419707

RHO1
GTP-binding protein RHO1

3

20

Small-scale

0.843

High

689357

ARP2
Actin-related protein 2

2

19

High-throughput

0.799

High

773853

BNR1
BNI1-related protein 1

2

13

Small-scale

0.757

High

783871

BUD6
Bud site selection protein 6

8

2

Small-scale

0.745

High

425515

PROF
Profilin

4

20

Small-scale

0.700

High

784614

ARP3
Actin-related protein 3

1

20

High-throughput

0.647

High

339693

CDK1
Cyclin-dependent kinase 1

3

0

Small-scale

0.641

High

491542

HSP71
Heat shock protein SSA1

3

7

High-throughput

0.641

High

784635

ZDS2
Protein ZDS2

3

1

High-throughput

0.639

High

494223

HSP72
Heat shock protein SSA2

3

7

High-throughput

0.633

High

636657

CDC48
Cell division control protein 48

2

6

High-throughput

0.628

High

784640

RHO3
GTP-binding protein RHO3

1

20

Small-scale

0.621

High

514635

FUS1
Nuclear fusion protein FUS1

2

1

Small-scale

0.603

High

784641

NUM1
Nuclear migration protein NUM1

2

8

Small-scale

0.601

High

784609

YFI6
Uncharacterized protein YFR016C

3

4

Small-scale

0.598

High

543928

HSC82
ATP-dependent molecular chaperone HSC82

2

5

High-throughput

0.595

High

784671

KAR
NADPH-dependent alpha-keto amide reductase

2

1

High-throughput

0.595

High

696460

FIMB
Fimbrin

2

2

Small-scale

0.594

High

710383

EDE1
EH domain-containing and endocytosis protein 1

2

3

Small-scale

0.594

High

784620

GYP3
GTPase-activating protein GYP3

2

3

Small-scale

0.594

High

731325

DYHC
Dynein heavy chain, cytoplasmic

2

1

Small-scale

0.584

High

765293

RSP5
E3 ubiquitin-protein ligase RSP5

1

4

Small-scale

0.578

High

730570

MYO3
Myosin-3

1

7

High-throughput

0.573

High

784642

CDC14
Tyrosine-protein phosphatase CDC14

1

6

Small-scale

0.561

High

613065

SPA2
Protein SPA2

1

3

Small-scale

0.552

High

368157

EF1A
Elongation factor 1-alpha

1

0

Small-scale

0.537

High

784652

TCB3
Tricalbin-3

1

2

High-throughput

0.536

High

743156

BOB1
Protein BOB1

1

2

Small-scale

0.527

High

743569

HMT1
Protein arginine N-methyltransferase 1

2

1

High-throughput

0.526

High

784656

MYO5
Myosin-5

1

7

High-throughput

0.508

High

784659

CYK2
Cytokinesis protein 2

1

11

Small-scale

0.508

High

420295

CALM
Calmodulin

1

4

High-throughput

0.501

High

526256

KIN2
Serine/threonine-protein kinase KIN2

1

2

High-throughput

0.501

High

528331

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.501

High

570702

HXKG
Glucokinase-1

1

1

High-throughput

0.501

High

629567

CDC10
Cell division control protein 10

1

3

High-throughput

0.501

High

635301

SYP1
Suppressor of yeast profilin deletion

1

1

High-throughput

0.501

High

659117

CAPZA
F-actin-capping protein subunit alpha

1

1

High-throughput

0.501

High

690217

CDC3
Cell division control protein 3

1

4

High-throughput

0.501

High

697955

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

2

High-throughput

0.501

High

731057

YKT6
Synaptobrevin homolog YKT6

1

1

High-throughput

0.501

High

748541

ARPC1
Actin-related protein 2/3 complex subunit 1

1

4

High-throughput

0.501

High

748808

RGD1
RHO GTPase-activating protein RGD1

1

5

High-throughput

0.501

High

755636

BZZ1
Protein BZZ1

1

11

High-throughput

0.501

High

761243

CAJ1
Protein CAJ1

1

4

High-throughput

0.501

High

764077

RV167
Reduced viability upon starvation protein 167

1

7

High-throughput

0.501

High

774594

PRK1
Actin-regulating kinase PRK1

1

3

Small-scale

0.501

High

784610

LSB3
LAS seventeen-binding protein 3

1

5

High-throughput

0.501

High

784612

AIP1
Actin-interacting protein 1

1

2

High-throughput

0.501

High

784628

TWF1
Twinfilin-1

1

1

High-throughput

0.501

High

784651

STE20
Serine/threonine-protein kinase STE20

1

2

Small-scale

0.501

High

784673

VPS13
Intermembrane lipid transfer protein VPS13

1

1

High-throughput

0.501

High

784684

AIM7
Protein AIM7

1

1

High-throughput

0.501

High

784691

MSB4
GTPase-activating protein MSB4

1

3

Small-scale

0.501

High

598418

MSB1
Morphogenesis-related protein MSB1

1

0

High-throughput

0.486

High

676136

XPO1
Exportin-1

1

4

Small-scale

0.481

High

765846

BOI2
Protein BOI2

1

3

Small-scale

0.481

High

767513

TSC11
Target of rapamycin complex 2 subunit TSC11

1

2

High-throughput

0.481

High

784616

SGM1
Protein SGM1

1

6

Small-scale

0.481

High

784626

MLC1
Myosin light chain 1

1

4

Small-scale

0.481

High

784645

OSH6
Oxysterol-binding protein homolog 6

1

2

Small-scale

0.481

High

562726

FUS3
Mitogen-activated protein kinase FUS3

1

0

Small-scale

0.480

High

568122

TPM1
Tropomyosin-1

1

0

High-throughput

0.480

High

612244

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.480

High

627634

NAP1
Nucleosome assembly protein

1

0

High-throughput

0.480

High

675268

LCF1
Long-chain-fatty-acid--CoA ligase 1

1

0

High-throughput

0.480

High

699351

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.480

High

703303

ARPC4
Actin-related protein 2/3 complex subunit 4

1

0

High-throughput

0.480

High

704583

NTF2
Nuclear transport factor 2

1

0

High-throughput

0.480

High

716041

GCS1
ADP-ribosylation factor GTPase-activating protein GCS1

1

0

High-throughput

0.480

High

742721

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

0

High-throughput

0.480

High

743103

AHP1
Peroxiredoxin AHP1

1

0

High-throughput

0.480

High

772537

SEC9
Protein transport protein SEC9

1

0

High-throughput

0.480

High

774919

MAM33
Mitochondrial acidic protein MAM33

1

0

High-throughput

0.480

High

775025

ARPC5
Actin-related protein 2/3 complex subunit 5

1

0

High-throughput

0.480

High

775146

GVP36
Protein GVP36

1

0

High-throughput

0.480

High

784648

COFI
Cofilin

1

0

High-throughput

0.480

High

784661

ARPC3
Actin-related protein 2/3 complex subunit 3

1

0

High-throughput

0.480

High

784675

ZEO1
Protein ZEO1

1

0

High-throughput

0.480

High

784693

PST2
Protoplast secreted protein 2

1

0

High-throughput

0.480

High

614687

KC11
Casein kinase I homolog 1

1

2

High-throughput

0.479

High

755694

DMA1
E3 ubiquitin-protein ligase DMA1

1

3

Small-scale

0.479

High

784634

DMA2
E3 ubiquitin-protein ligase DMA2

1

3

Small-scale

0.479

High

145911

YO304
Uncharacterized protein YOR304C-A

1

0

Small-scale

0.460

High

586247

EXO70
Exocyst complex component EXO70

1

0

Small-scale

0.460

High

699232

SEC8
Exocyst complex component SEC8

1

0

Small-scale

0.460

High

732091

SHE2
SWI5-dependent HO expression protein 2

1

0

Small-scale

0.460

High

784639

SEC5
Exocyst complex component SEC5

1

0

Small-scale

0.460

High

767002

FIR1
Factor interacting with REF2

1

0

High-throughput

0.458

High

784625

YIP5
Protein YIP5

1

0

High-throughput

0.458

High

784649

YD090
Uncharacterized membrane protein YDR090C

1

0

High-throughput

0.458

High

784658

DYN3
Cytoplasmic dynein intermediate light chain DYN3

1

0

High-throughput

0.458

High

784667

GIC2
GTPase-interacting component 2

1

0

Small-scale

0.458

High

784672

FMP45
SUR7 family protein FMP45

1

0

High-throughput

0.458

High

342048

ATPB
ATP synthase subunit beta, mitochondrial

1

2

High-throughput

0.457

High

454619

TBA3
Tubulin alpha-3 chain

1

4

High-throughput

0.457

High

456707

RIR2
Ribonucleoside-diphosphate reductase small chain 1

1

1

High-throughput

0.457

High

554674

HSP26
Heat shock protein 26

1

1

High-throughput

0.457

High

556116

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.457

High

594408

SAR1
Small COPII coat GTPase SAR1

1

7

High-throughput

0.457

High

599184

RIR1
Ribonucleoside-diphosphate reductase large chain 1

1

1

High-throughput

0.457

High

599975

RIR3
Ribonucleoside-diphosphate reductase large chain 2

1

1

High-throughput

0.457

High

628179

SIS1
Protein SIS1

1

4

High-throughput

0.457

High

649277

CBPS
Carboxypeptidase S

1

1

High-throughput

0.457

High

657080

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

1

High-throughput

0.457

High

660919

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

1

High-throughput

0.457

High

728852

KES1
Oxysterol-binding protein homolog 4

1

2

High-throughput

0.457

High

731703

SDS22
Protein phosphatase 1 regulatory subunit SDS22

1

2

High-throughput

0.457

High

784611

DUG1
Cys-Gly metallodipeptidase DUG1

1

1

High-throughput

0.457

High

784613

BBC1
Myosin tail region-interacting protein MTI1

1

3

High-throughput

0.457

High

784622

RIR4
Ribonucleoside-diphosphate reductase small chain 2

1

1

High-throughput

0.457

High

784654

SNX41
Sorting nexin-41

1

4

High-throughput

0.457

High

784664

CORO
Coronin-like protein

1

3

High-throughput

0.457

High

784668

UBX5
UBX domain-containing protein 5

1

1

High-throughput

0.457

High

784681

SGT2
Small glutamine-rich tetratricopeptide repeat-containing protein 2

1

3

High-throughput

0.457

High

784690

YD061
Uncharacterized ABC transporter ATP-binding protein YDR061W

1

2

High-throughput

0.457

High

784692

HSP42
Heat shock protein 42

1

1

High-throughput

0.457

High

366454

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.445

High

450080

HSP73
Heat shock protein SSA3

1

7

High-throughput

0.445

High

511687

SSB1
Ribosome-associated molecular chaperone SSB1

1

7

High-throughput

0.445

High

768691

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.445

High

628673

CANB
Calcineurin subunit B

1

3

Small-scale

0.439

High

655718

PRP45
Pre-mRNA-processing protein 45

1

3

Small-scale

0.439

High

703657

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.439

High

784629

YG3A
Uncharacterized protein YGR130C

1

8

High-throughput

0.439

High

784647

CENPP
Inner kinetochore subunit CTF19

1

1

High-throughput

0.439

High

597582

FAR1
Cyclin-dependent kinase inhibitor FAR1

1

0

Small-scale

0.438

High

141388

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.437

High

662509

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

730480

NNK1
Nitrogen network kinase 1

1

2

High-throughput

0.437

High

750979

KPR2
Ribose-phosphate pyrophosphokinase 2

1

1

High-throughput

0.437

High

752071

KPR3
Ribose-phosphate pyrophosphokinase 3

1

1

High-throughput

0.437

High

784617

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

1

1

High-throughput

0.437

High

784638

H3
Histone H3

1

6

High-throughput

0.437

High

784646

MLP1
Protein MLP1

1

3

High-throughput

0.437

High

784695

CMR1
DNA damage-binding protein CMR1

1

1

High-throughput

0.437

High

741420

PAM1
Protein PAM1

1

0

High-throughput

0.426

High

784688

NCE2
Non-classical export protein 2

1

0

High-throughput

0.426

High

576235

ERD2
ER lumen protein-retaining receptor

1

1

High-throughput

0.407

High

595039

NUP1
Nucleoporin NUP1

1

3

High-throughput

0.407

High

633309

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.407

High

659170

LAC1
Ceramide synthase LAC1

1

1

High-throughput

0.407

High

680791

HS104
Heat shock protein 104

1

2

High-throughput

0.407

High

694901

HSP7F
Heat shock protein homolog SSE1

1

8

High-throughput

0.407

High

705301

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.407

High

784615

DPH4
Diphthamide biosynthesis protein 4

1

4

High-throughput

0.407

High

784680

FAL1
ATP-dependent RNA helicase FAL1

2

0

High-throughput

0.307

High

784607

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.279

Low

784630

RT35
Small ribosomal subunit protein mS45

1

0

High-throughput

0.279

Low

336246

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

High-throughput

0.261

Low

336685

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.261

Low

336726

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.261

Low

341719

HIS2
Histidine biosynthesis trifunctional protein [Includes: Phosphoribosyl-AMP cyclohydrolase

1

0

High-throughput

0.261

Low

341814

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.261

Low

423469

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.261

Low

478674

IPB2
Protease B inhibitor 2

1

0

High-throughput

0.261

Low

536294

CPYI
Carboxypeptidase Y inhibitor

1

0

High-throughput

0.261

Low

561802

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.261

Low

572796

PDI
Protein disulfide-isomerase

1

0

High-throughput

0.261

Low

630679

NFS1
Cysteine desulfurase, mitochondrial

1

0

High-throughput

0.261

Low

679713

CYS3
Cystathionine gamma-lyase

1

0

High-throughput

0.261

Low

698315

COX13
Cytochrome c oxidase subunit 13, mitochondrial

1

0

High-throughput

0.261

Low

710421

PIN4
RNA-binding protein PIN4

1

0

High-throughput

0.261

Low

727994

MRP8
Uncharacterized protein MRP8

1

0

High-throughput

0.261

Low

739491

PGM2
Phosphoglucomutase 2

1

0

High-throughput

0.261

Low

748317

SDS24
Protein SDS24

1

0

High-throughput

0.261

Low

750086

CUE1
Coupling of ubiquitin conjugation to ER degradation protein 1

1

0

High-throughput

0.261

Low

755276

SDO1L
Restriction of telomere capping protein 3

1

0

High-throughput

0.261

Low

760631

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.261

Low

763163

FHP
Flavohemoprotein

1

0

High-throughput

0.261

Low

770018

YNU8
Uncharacterized protein YNL208W

1

0

High-throughput

0.261

Low

771334

PSA6
Proteasome subunit alpha type-6

1

0

High-throughput

0.261

Low

784606

GSHR
Glutathione reductase

1

0

High-throughput

0.261

Low

784608

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.261

Low

784633

YNN4
Uncharacterized protein YNL134C

1

0

High-throughput

0.261

Low

784643

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

1

0

High-throughput

0.261

Low

784655

YM54
Uncharacterized protein YMR196W

1

0

High-throughput

0.261

Low

784657

IVY1
Protein IVY1

1

0

High-throughput

0.261

Low

784660

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.261

Low

784669

PEX19
Peroxisomal membrane protein import receptor PEX19

1

0

High-throughput

0.261

Low

784674

MTAP
S-methyl-5'-thioadenosine phosphorylase

1

0

High-throughput

0.261

Low

784676

CUE5
Ubiquitin-binding protein CUE5

1

0

High-throughput

0.261

Low

784677

MCA1
Metacaspase-1

1

0

High-throughput

0.261

Low

784682

DCS2
Inactive diphosphatase DCS2

1

0

High-throughput

0.261

Low

784685

ATPD
ATP synthase subunit delta, mitochondrial

1

0

High-throughput

0.261

Low

784689

MDY2
Ubiquitin-like protein MDY2

1

0

High-throughput

0.261

Low

784696

HUG1
MEC1-mediated checkpoint protein HUG1

1

0

High-throughput

0.261

Low

604433

CLH
Clathrin heavy chain

1

0

Small-scale

0.251

Low

765880

ACA1
ATF/CREB activator 1

1

0

High-throughput

0.251

Low

784621

BRO1
Vacuolar-sorting protein BRO1

1

0

High-throughput

0.251

Low

784627

SP105
Spindle pole body component SPC105

1

0

High-throughput

0.251

Low

784666

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.251

Low

140784

FOB1
DNA replication fork-blocking protein FOB1

1

0

High-throughput

0.249

Low

407121

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

527017

TBP
TATA-box-binding protein

1

0

High-throughput

0.249

Low

549676

BGL2
Glucan 1,3-beta-glucosidase

1

0

High-throughput

0.249

Low

631937

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

635995

SRB8
Mediator of RNA polymerase II transcription subunit 12

1

0

High-throughput

0.249

Low

667593

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.249

Low

668160

RIF1
Telomere length regulator protein RIF1

1

0

High-throughput

0.249

Low

700946

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

716118

THI80
Thiamine pyrophosphokinase

1

0

High-throughput

0.249

Low

733070

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.249

Low

745614

YBI1
Uncharacterized protein YBL081W

1

0

High-throughput

0.249

Low

746833

TRM7
tRNA

1

0

High-throughput

0.249

Low

748147

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

748283

CENPU
Inner kinetochore subunit AME1

1

0

High-throughput

0.249

Low

757992

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

762299

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

767097

PHM8
Phosphate metabolism protein 8

1

0

High-throughput

0.249

Low

772251

RFC4
Replication factor C subunit 4

1

0

High-throughput

0.249

Low

784619

BUL1
Ubiquitin ligase-binding protein BUL1

1

0

High-throughput

0.249

Low

784623

RL4P
Large ribosomal subunit protein uL4m

1

0

High-throughput

0.249

Low

784624

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

0

High-throughput

0.249

Low

784631

BUD17
Putative pyridoxal kinase BUD17

1

0

High-throughput

0.249

Low

784636

DOS2
Protein DOS2

1

0

High-throughput

0.249

Low

784644

MTD1
Methylenetetrahydrofolate dehydrogenase [NAD(+)]

1

0

High-throughput

0.249

Low

784650

DIG2
Down-regulator of invasive growth 2

1

0

High-throughput

0.249

Low

784653

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

784662

YL257
Uncharacterized protein YLR257W

1

0

High-throughput

0.249

Low

784663

YPQ2
Vacuolar arginine/histidine antiporter YPQ2

1

0

High-throughput

0.249

Low

784665

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

784670

YD073
UPF0592 protein YDL073W

1

0

High-throughput

0.249

Low

784678

PMG2
Phosphoglycerate mutase 2

1

0

High-throughput

0.249

Low

784679

TSR3
18S rRNA aminocarboxypropyltransferase

1

0

High-throughput

0.249

Low

784683

CMR3
Zinc finger protein CRM3

1

0

High-throughput

0.249

Low

784686

RFM1
Repression factor of MSEs protein 1

1

0

High-throughput

0.249

Low

784687

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.249

Low

784694

YPR1
Putative reductase 1

1

0

High-throughput

0.249

Low

141942

YP089
Dilute domain-containing protein YPR089W

1

0

High-throughput

0.232

Low

633867

SGF29
SAGA-associated factor 29

1

0

High-throughput

0.232

Low

756686

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.232

Low

765749

PP2C2
Protein phosphatase 2C homolog 2

1

0

High-throughput

0.232

Low

784618

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.232

Low

784632

LTO1
Protein LTO1

1

0

High-throughput

0.232

Low

784697

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024