Protein: H1
Histone H1

Gene: H1, HHO1
Organism: Saccharomyces cerevisiae S288C
Interactions: 163
UniProt ID: P53551

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000786 - nucleosome
GO:0003676 - nucleic acid binding
GO:0003677 - DNA binding
GO:0003690 - double-stranded DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

339768

CDK1
Cyclin-dependent kinase 1

8

0

Small-scale

0.716

High

862754

H2AZ
Histone H2A.Z

4

1

Small-scale

0.685

High

862724

H3
Histone H3

3

0

Small-scale

0.626

High

514197

NHP6A
Non-histone chromosomal protein 6A

2

1

Small-scale

0.613

High

764211

NOC2
Nucleolar complex protein 2

2

0

High-throughput

0.587

High

862722

MOT3
Transcriptional activator/repressor MOT3

2

0

High-throughput

0.583

High

606088

RAD53
Serine/threonine-protein kinase RAD53

2

0

Small-scale

0.569

High

356623

H4
Histone H4

2

0

High-throughput

0.547

High

392518

H2A2
Histone H2A.2

2

0

High-throughput

0.547

High

772307

ATAD2
ATPase histone chaperone YTA7

2

0

High-throughput

0.547

High

141448

RS9A
Small ribosomal subunit protein uS4A

2

1

High-throughput

0.533

High

405744

RL26A
Large ribosomal subunit protein uL24A

2

1

High-throughput

0.533

High

472314

RL31A
Large ribosomal subunit protein eL31A

2

1

High-throughput

0.533

High

862725

ARP4
Actin-related protein 4

1

0

Small-scale

0.529

High

615169

BUR1
Serine/threonine-protein kinase BUR1

1

1

High-throughput

0.515

High

604304

MAG
DNA-3-methyladenine glycosylase

1

0

High-throughput

0.513

High

862727

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

862736

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.513

High

605565

DBF2
Cell cycle protein kinase DBF2

1

1

Small-scale

0.501

High

693732

IME2
Meiosis induction protein kinase IME2/SME1

1

1

Small-scale

0.501

High

612173

APN1
Apurinic-apyrimidinic endonuclease 1

1

0

High-throughput

0.493

High

755747

ORC6
Origin recognition complex subunit 6

1

0

High-throughput

0.493

High

757859

HRB1
Serine/arginine

1

0

High-throughput

0.493

High

514263

NHP6B
Non-histone chromosomal protein 6B

1

1

Small-scale

0.481

High

624705

CG22
G2/mitotic-specific cyclin-2

1

0

Small-scale

0.480

High

756056

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.480

High

862743

RT109
Histone acetyltransferase RTT109

1

0

Small-scale

0.480

High

499015

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.479

High

829645

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.479

High

859253

INO80
Chromatin-remodeling ATPase INO80

1

1

Small-scale

0.479

High

862721

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.479

High

381564

GAL4
Regulatory protein GAL4

1

0

Small-scale

0.460

High

862751

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.460

High

419489

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

558177

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

579809

SNF6
Transcription regulatory protein SNF6

1

0

Small-scale

0.458

High

601764

RCC1
Guanine nucleotide exchange factor SRM1

1

0

Small-scale

0.458

High

606711

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

630232

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

641019

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.458

High

688347

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

692581

ZUO1
Zuotin

1

0

High-throughput

0.458

High

698890

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

716304

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

742916

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

754588

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.458

High

756698

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.458

High

759413

STM1
Suppressor protein STM1

1

0

High-throughput

0.458

High

775800

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

797748

IOC3
ISWI one complex protein 3

1

0

Small-scale

0.458

High

862720

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

862732

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.458

High

862740

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

862745

SGO1
Shugoshin

1

0

High-throughput

0.458

High

862749

RPIA
Ribose-5-phosphate isomerase

1

0

High-throughput

0.458

High

862755

HAA1
Transcriptional activator HAA1

1

0

High-throughput

0.458

High

862756

RL11B
Large ribosomal subunit protein uL5B

1

0

High-throughput

0.458

High

687590

DBF20
Serine/threonine-protein kinase DBF20

1

1

Small-scale

0.457

High

416315

SIR3
Regulatory protein SIR3

1

1

High-throughput

0.445

High

457049

SWI6
Regulatory protein SWI6

1

1

High-throughput

0.445

High

512185

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

628881

SWI4
Regulatory protein SWI4

1

1

High-throughput

0.445

High

706982

MSN2
Zinc finger protein MSN2

1

1

High-throughput

0.445

High

707039

MSN4
Zinc finger protein MSN4

1

1

High-throughput

0.445

High

769049

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

862729

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

2

High-throughput

0.445

High

862738

SWR1
Helicase SWR1

1

1

High-throughput

0.445

High

862739

FKBP4
FK506-binding protein 4

1

0

High-throughput

0.438

High

357540

RLA4
Large ribosomal subunit protein P2B

1

1

High-throughput

0.437

High

399775

RLA1
Large ribosomal subunit protein P1A

1

1

High-throughput

0.437

High

399908

RLA2
Large ribosomal subunit protein P2A

1

1

High-throughput

0.437

High

404654

RL7A
Large ribosomal subunit protein uL30A

1

1

High-throughput

0.437

High

404884

RL9A
Large ribosomal subunit protein uL6A

1

1

High-throughput

0.437

High

405043

RL6B
Large ribosomal subunit protein eL6B

1

1

High-throughput

0.437

High

405238

RL17A
Large ribosomal subunit protein uL22A

1

1

High-throughput

0.437

High

406584

RL22A
Large ribosomal subunit protein eL22A

1

1

High-throughput

0.437

High

407564

RS9B
Small ribosomal subunit protein uS4B

1

1

High-throughput

0.437

High

472517

RL31B
Large ribosomal subunit protein eL31B

1

1

High-throughput

0.437

High

496075

RLA3
Large ribosomal subunit protein P1B

1

1

High-throughput

0.437

High

564337

RL8A
Large ribosomal subunit protein eL8A

1

1

High-throughput

0.437

High

645087

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.437

High

645249

RL16B
Large ribosomal subunit protein uL13B

1

1

High-throughput

0.437

High

667241

RL8B
Large ribosomal subunit protein eL8B

1

1

High-throughput

0.437

High

700541

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.437

High

732760

RL14A
Large ribosomal subunit protein eL14A

1

1

High-throughput

0.437

High

753686

RL14B
Large ribosomal subunit protein eL14B

1

1

High-throughput

0.437

High

770423

RL13B
Large ribosomal subunit protein eL13B

1

1

High-throughput

0.437

High

775070

RL34B
Large ribosomal subunit protein eL34B

1

1

High-throughput

0.437

High

804815

RSSA2
Small ribosomal subunit protein uS2B

1

1

High-throughput

0.437

High

810270

RL17B
Large ribosomal subunit protein uL22B

1

1

High-throughput

0.437

High

846293

RL9B
Large ribosomal subunit protein uL6B

1

1

High-throughput

0.437

High

860235

RL26B
Large ribosomal subunit protein uL24B

1

1

High-throughput

0.437

High

862723

RL22B
Large ribosomal subunit protein eL22B

1

1

High-throughput

0.437

High

862726

RL34A
Large ribosomal subunit protein eL34A

1

1

High-throughput

0.437

High

862730

RL6A
Large ribosomal subunit protein eL6A

1

1

High-throughput

0.437

High

862741

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

1

Small-scale

0.437

High

862750

RL7B
Large ribosomal subunit protein uL30B

1

1

High-throughput

0.437

High

862753

RL13A
Large ribosomal subunit protein eL13A

1

1

High-throughput

0.437

High

355570

H2B1
Histone H2B.1

1

0

High-throughput

0.426

High

419368

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.426

High

491978

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

605247

AFT1
Iron-regulated transcriptional activator AFT1

1

0

High-throughput

0.426

High

609118

SIN3
Transcriptional regulatory protein SIN3

1

0

High-throughput

0.426

High

650348

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.426

High

689922

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.426

High

692856

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.426

High

699397

RGT1
Glucose transport transcription regulator RGT1

1

0

High-throughput

0.426

High

732678

SWD2
COMPASS component SWD2

1

0

High-throughput

0.426

High

733279

SET3
SET domain-containing protein 3

1

0

High-throughput

0.426

High

770096

RT106
Histone chaperone RTT106

1

0

High-throughput

0.426

High

862733

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.426

High

862734

HOS3
Histone deacetylase HOS3

1

0

High-throughput

0.426

High

862735

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.426

High

862737

RCO1
Transcriptional regulatory protein RCO1

1

0

High-throughput

0.426

High

862742

BRE1
E3 ubiquitin-protein ligase BRE1

1

0

High-throughput

0.426

High

862744

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

862746

ESA1
Histone acetyltransferase ESA1

1

0

High-throughput

0.426

High

862752

RLF2
Chromatin assembly factor 1 subunit p90

1

0

High-throughput

0.426

High

383267

RL25
Large ribosomal subunit protein uL23

2

0

High-throughput

0.305

High

655870

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

0

High-throughput

0.282

High

862748

ENV7
Serine/threonine-protein kinase ENV7

1

0

Small-scale

0.261

Low

140789

FOB1
DNA replication fork-blocking protein FOB1

1

0

Small-scale

0.249

Low

145764

RL36B
Large ribosomal subunit protein eL36B

1

0

High-throughput

0.249

Low

358181

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

399574

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.249

Low

406035

RL33A
Large ribosomal subunit protein eL33A

1

0

High-throughput

0.249

Low

406381

RL15A
Large ribosomal subunit protein eL15A

1

0

High-throughput

0.249

Low

408034

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

413631

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

426070

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

450485

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.249

Low

471173

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

471921

RL27B
Large ribosomal subunit protein eL27B

1

0

High-throughput

0.249

Low

478941

RL20B
Large ribosomal subunit protein eL20B

1

0

High-throughput

0.249

Low

479148

RL43B
Large ribosomal subunit protein eL43B

1

0

High-throughput

0.249

Low

621497

RL24B
Large ribosomal subunit protein eL24B

1

0

High-throughput

0.249

Low

480228

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

480795

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

481678

RL18B
Large ribosomal subunit protein eL18B

1

0

High-throughput

0.249

Low

481961

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.249

Low

482378

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

482761

RL19B
Large ribosomal subunit protein eL19

1

0

High-throughput

0.249

Low

482906

RL35A
Large ribosomal subunit protein uL29A

1

0

High-throughput

0.249

Low

535065

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.249

Low

632002

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

634710

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

638824

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.249

Low

645565

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

730040

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

745796

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

752579

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

761996

DHH1
ATP-dependent RNA helicase DHH1

1

0

High-throughput

0.249

Low

762423

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

784182

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.249

Low

805053

ARC1
tRNA-aminoacylation cofactor ARC1

1

0

High-throughput

0.249

Low

820085

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

824746

RL37A
Large ribosomal subunit protein eL37A

1

0

High-throughput

0.249

Low

862718

GIS2
Zinc finger protein GIS2

1

0

High-throughput

0.249

Low

862728

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

862731

RL21A
Large ribosomal subunit protein eL21A

1

0

High-throughput

0.249

Low

862747

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

805159

STU2
Protein STU2

1

0

High-throughput

0.232

Low

862719

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024